Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56584	Diphenoxylate	GSE92742	HA1E	Human	6h	10uM	EID0287

Response Information :

Types	Number	Response transcription factors
Up-regulation	323	RSF1; IKZF3; ZNF701; YEATS4; WHSC1L1; EGR3; ZNF136; ZNF529; GATA3; ZNF432; STAT2; ZNF287; LZTS1; MDM2; TFAP2B; ZNF675; ZNF721; HIPK2; MEF2C; ZNF506; ZFP30; ZBTB39; EED; EYA3; TFDP2; ZNF460; ZNF329; NFATC4; ZNF266; NFAT5; CEBPG; ZNF222; SSX1; EGR2; BHLHE41; ZNF764; TAF1A; TRPS1; MXD1; ELK4; SMARCD2; ZNF354A; BRWD1; ZNF226; ARNT; TCF7; EBF2; FOXA1; L3MBTL1; IKZF2; NR4A2; SKI; CHD2; PPARD; HLTF; FEV; NFATC1; RARG; ZNF443; RFX7; ZNF492; CBFA2T2; ZNF165; NCOA2; TRIM33; ZNF10; NKX2-1; ID4; ZNF331; JUNB; NCOA3; XBP1; PKNOX1; ING2; ZNF562; ZNF813; ZNF43; ZSCAN18; PHIP; PLAG1; ZNF695; ZNF141; FOXN2; URI1; AGO2; HIVEP2; THAP1; ZNF286A; EGR4; SUV39H1; NFIL3; ZNF629; MDM4; ZNF835; TDRD3; KLF6; ZNF415; SP4; TTF2; ADRB2; ZNF571; PIR; TXNIP; LEF1; TBX2; ZNF816; ELF3; BACH2; MED21; ID3; ESR1; ZKSCAN8; NKX3-1; ASH1L; RERE; SMARCA4; HCFC2; ZKSCAN1; EHMT1; TBX19; SMARCA1; SMARCA5; HDAC9; MSL3; KDM5A; RORC; ZNF223; RBPJ; CREM; TAF1D; NKX2-2; NRBF2; PPARG; BRCA1; ZNF350; ZNF160; BCLAF1; GCM1; ZNF528; ZNF91; ZNF586; TSC22D1; RUNX1; AIP; HLX; ZNF711; ZNF587; ZNF493; ATF6; NKX2-5; ZNF623; TMF1; CCNE1; ZNF440; ZNF214; ZNF157; NR2F6; EMX2; NFIX; IFNB1; ELF4; WWP1; ZNF334; ZNF180; ZBTB3; CBFA2T3; PEX14; ZNF273; TADA2A; GATA2; STAT5A; ZNF611; HOXC10; NR4A1; FOXO4; NCOA1; ZNF236; ZFP64; ZNF672; PAWR; AFF4; E2F5; MITF; ZBTB25; ZIC1; GFI1; PBX2; SP100; CAMTA2; ZNF22; RNF141; KLF4; MBD4; KMT2A; MNT; HOXC4; KLF9; CBX6; ZNF614; BCL10; ZNF302; CUX2; ZNF83; RBL1; POU4F1; LHX3; ID1; E2F3; ZNF264; HMGA2; CERS6; NFATC3; CREBZF; MAK; CCNH; HSF2; IL16; SREBF1; PRKDC; HES1; VPS72; MNDA; CUX1; SERTAD2; MAF; BNC2; TEAD1; PBX3; HOXC6; SOHLH2; KAT8; ZNF117; NCOA6; ZNF274; KDM5D; MED4; ZBED2; AHR; MYT1L; PAX8; GABPB1; SIX3; NR4A3; TAF5; HMG20B; PPP1R13L; CTR9; REST; SOX4; IFI16; TTF1; ZNF665; FLI1; SFMBT1; SMAD2; BRIP1; ZNF667; MYBL2; BACH1; PLAGL2; NR1D2; ZNF430; NR3C1; MTDH; HOXB7; PATZ1; CTNNB1; ADNP; BAZ1A; MBD2; RNF14; FOSB; HOXB2; PLAGL1; CLOCK; SPDEF; BHLHE40; ZNF93; MED14; TAF1; AFF1; SMAD5; HDAC6; ZNF669; GLI3; STAT3; TAF9B; RELB; FOXE1; KLF3; MYCBP; ETS1; ASCL1; SOX10; HIVEP1; CBX7; JAK2; SNAI2; HIPK3; SOX17; PEG3; EDF1; NEUROD1; HEY1; EHF; WT1; HOXB6; ECD; IRX5; NUP62; ZBTB18; TRIB3; TWIST1; KLF10; NFE2; RB1; EPAS1; NFE2L2; MECOM; FOS; INSM1; ARID5B; CRK
Down-regulation	388	PSIP1; HOXA10; THAP11; EZH2; IKBKAP; ABL1; APEX1; FOXO3; CENPB; HMGB2; CTCF; ZNF444; ZNF500; MED15; ITGB3BP; SIRT7; ZSCAN5A; ERCC3; TFAP2A; KDM4C; CASZ1; SMAD7; CERS4; MED16; HOXA7; SP3; SAFB2; ATF4; RBM39; ZNF202; SMARCD1; HDAC3; SUB1; ZNF446; TCF25; XRCC6; CIC; NR0B1; ZNF276; ZNF335; ADNP2; MEF2A; ZNF324; ARL2BP; HMGXB3; UBE2L3; TGFB1; CBX4; ATF1; ZNF263; CENPF; ZNF410; HEYL; CITED2; SREBF2; HMGB1; THAP4; CNOT1; TBP; BLM; ETV4; ARID5A; FOXM1; MAML1; MDFI; PSMC3IP; ATF5; GTF3A; CBX3; SOX15; TRIM32; ZBTB17; PMS1; MKL1; CCNC; SF1; RNF10; SUPT6H; CIZ1; CDK9; E2F4; ETV1; HSBP1; UBP1; TEAD3; TSC22D3; AIRE; AES; TAF1C; BAZ2B; SMAD3; PTTG1; SIN3B; TCF3; USP21; TBPL1; ZFP36L1; TAF6; ZNF408; CNOT3; ESRRB; EP300; HOXA11; POLR2A; TBX10; CHAF1B; PSPC1; VSX1; PBX1; NKX2-8; ZKSCAN5; ZNF787; ZNF282; KAT2A; CAPN15; ZNF473; NOC2L; CHD1; HOXD9; NFKBIB; ALX3; IKZF4; IRX4; ZBED1; HDAC5; TULP3; BARX1; SAFB; EWSR1; NPAS1; TCF12; HOXA6; ZNF12; WHSC1; HOXA4; HINFP; CHD8; MED13; TFCP2; SRCAP; TCEA1; GATA6; SALL1; MTA2; RBFOX2; ATF2; TLE2; BTF3; LHX1; TERF2; SAP130; CRX; TADA3; ZSCAN32; FOXF2; HIVEP3; ZZZ3; NR0B2; TCEB2; E4F1; NFIC; ZNF384; FOXN3; GMEB1; TCF15; RBM14; ZNF250; RUVBL2; PCGF1; RREB1; PRRX2; MEIS1; IRF3; PIAS1; HIRA; HMGN3; IRF2; CRY1; ZNF8; SUPT3H; RBBP4; NONO; CBFB; RCOR1; SUPT4H1; RXRA; PTRF; ERF; SNW1; KLF2; GLI1; VAX2; APBB1; MBD3; ZFHX2; TRIM28; ZNF668; NCOA4; PRDM12; TRIM16; MED17; ERBB2; ZBTB16; ATN1; NKRF; GCFC2; DEK; HOXB9; CEBPE; CALCOCO1; ZNF532; EN1; ZNF292; ZNF76; TRIM24; ELF2; ZNF148; FOXK2; TRIP6; THAP7; ZNF593; TRAF6; POU2F2; ZMIZ1; CNBP; SOX9; CXXC1; NR5A2; CDK8; JUND; C1QBP; PBXIP1; LZTR1; AATF; ZBTB11; REPIN1; RING1; PMF1; TAF4; POU3F2; IRF8; ZMIZ2; MED24; SPEN; MLX; TBX3; UIMC1; NR1I3; EGR1; MTF2; DAXX; POU5F1B; PRDM14; PHF1; GATAD2A; CREB5; MNAT1; SMAD1; SP140L; TFE3; SOX11; UBE2B; SETD3; ZNF580; RELA; NFRKB; NELFB; ZNF358; PAXBP1; FOXF1; ZNF133; ZNF692; RNF6; RNF138; PHOX2B; ZNF232; RCOR3; MSX1; SLC2A4RG; TFEB; REXO4; NFE2L1; TCF7L2; ATF3; RBBP7; ING3; RNF4; CREB3; NAB1; ZNF189; MAZ; UBE2I; ZNF337; PDLIM1; SCMH1; MYRF; MED20; HOXB13; DDIT3; SAP30; BAZ1B; BATF3; ZKSCAN3; SMAD6; DLX2; ZBTB7A; NPAS2; BTG1; RFXANK; TRIM29; RBBP8; RFX5; ELF1; CDYL; USP16; POU2AF1; BRD2; TOX; HOXD10; STAT1; TAF10; BANP; MED27; NPM1; BRD4; IRF7; TSC22D4; TGIF1; TCF4; DACH1; TP63; ZNF131; NCOR2; ZMYM2; TLE4; TOX3; ARNTL2; MEIS2; ZNF140; BRD3; TAF9; MYBL1; TRAK1; PPARGC1A; ZNF544; NR2F2; HLF; SMARCD3; CTBP1; LITAF; ZNF423; SATB2; MYCL; WWC1; ZNF589; ZNF24; SSBP3; TCF21; ZEB1; CREB1; LYL1; ZBTB38; HOXA5; E2F6; KAT2B; HAND1; CEBPZ; STAT6; CARHSP1; VGLL4; BCL11A; WWTR1; ARID4B; PAX5; EYA1; CHD9; ZFP36L2; JUP; TOB1; BIRC2; ST18; SIX2; ID2; TGFB1I1; MXI1; SIAH2; SCAND1; MTA1