Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56380	Maprotiline	GSE92742	HA1E	Human	6h	10uM	EID0286

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	HDAC6; PPP1R13L; ZBTB38; ZSCAN31; KDM5A; HOXC6; ATF7IP; PTTG1; MED1; NCOA4; FOXO4; GATA3; BCLAF1; RXRA; TFAM; NFIL3; PPARGC1A; SOX4; CD3D; SMAD6; TRIM16; PIR; NUP62; BMI1; EDF1; RBM14; NEDD8; BRPF1; SMAD5; PSIP1; SND1; ID2; SIM2; CRK; CTR9; HLTF; JARID2; VGLL4; KLF4; RBPMS; MED23; ZMIZ2; ZBTB20; MED24; UBE2L3; SUV39H1; ENO1; NR1D2; RBBP4; TSC22D2; DNAJC1; BCL11B; NCOR2; NR3C2; LMCD1; SMAD2; STAT1; MED6; PITX1; BHLHE40; RHOA; TRIP6; NR2F2; ETS2; MXD4; BTG1; ZNF226; BASP1; SETD3; MAGED1; MITF; SUB1; HTATIP2; PBRM1; FOXN3; KLF2; KLF6; SAP18; AHR; RORA; TFEC; HOXC10; MTF2; TCF4; CRY1; EZH2; MAF; HOXB7; ATF1; IRF8; ARID4B; IKBKAP; KDM5D; HOXA5; TOB1; SOX9; GTF2A2; CREB1; NKX3-1
Down-regulation	85	ZNF232; SOX17; RB1; TRIB3; SP3; SOX2; DLX2; E2F4; ZFP36L1; ARNT2; MDM2; SOX3; ZHX2; ZNF580; MXI1; PAX5; ELF4; PEX2; ARID1A; FOXK2; TGIF2; ZNF217; TAF5L; ETV1; IFI16; CCNH; ZNF816; RREB1; HMGA1; HOXB2; MYBL2; ZNF215; TGFB1; DLX5; RAD21; ZNF354A; VPS72; NKX2-1; ATN1; FLI1; ETS1; SOX13; TFAP2C; AR; ERBB4; HIPK1; LIN28A; ZNF43; HOXD1; NANOG; ZNF654; PBX3; PRRX1; ZNF195; SOHLH2; ESR1; ZNF331; CBFA2T2; KDM5C; TTF2; JUN; HDAC9; CEBPD; CHD7; ZFP36L2; PFDN5; POU2AF1; NRIP1; FOS; MLXIP; MYBL1; TRPS1; FOXF2; HHEX; ZNF117; ELK3; ZNF589; SSBP2; FOXF1; INSR; NFATC4; ZBTB16; HIRA; NFE2L3; ZNF586