Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56289	Pinacidil	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	311	MEIS1; CDC5L; NFIC; ZNF83; ZBTB11; JUND; NCOR1; CARM1; CNOT3; ATF3; HIPK1; TRIM27; BTAF1; CRY1; CALR; MITF; RBFOX2; AES; CTCF; TCEA1; NONO; CCNC; PSIP1; HBP1; SMARCD1; CSDE1; CHD9; CBX4; RFC1; TCF12; ZNF266; DEK; ZBTB38; TFAP2A; MBD3; JARID2; SREBF2; PBRM1; NKX3-1; MED16; CHD8; NR0B1; LOXL2; PA2G4; ZNF593; ZNF573; CENPB; FOXM1; RLF; TRIM16; SMAD4; MED15; RBPMS; INSR; TERF1; APBB1; EMX2; XRCC6; SOX9; NAB1; TFE3; TAF6; ZBTB17; KAT2A; FOXF2; GABPB1; ZNF91; EHMT2; DDX17; NELFB; PRDM4; ATF2; MTA1; CBX3; KLF6; TCF7L2; DNMT3B; ATF4; TBX10; MED4; SAFB2; NR2C1; HDAC2; HSF1; PAX6; ZNF302; MED20; ZNF586; HMGB1; MMS19; ZNF12; SREBF1; ETS2; ZNF177; SUB1; RYBP; SMARCA4; RAD21; ARID1A; ZNF133; ZNF268; CARHSP1; SMARCB1; SRF; IKBKAP; INSM1; RBBP8; ATN1; IFI16; TGFB1; TDRD3; TOX; SAP18; TRIP6; HOXA10; BAZ1B; MKL1; PBX1; SND1; ARNT; HDAC5; SSRP1; NOC2L; TSC22D2; TULP3; ZNF232; ECD; BARX2; SLC2A4RG; KDM4C; FLNA; NR4A3; RAN; SMARCC2; MGA; CREBL2; AFF1; ZNF335; ZNF580; ATF1; HOXA7; MSX1; POU5F1B; STAT6; CERS4; ARID5A; TGFB1I1; CAPN15; CNOT1; HOXB13; TCF3; PMF1; PTRF; ZNF219; ZFX; RBBP4; REST; SCAND1; ZNF131; CDYL; MED23; TOPORS; MYBBP1A; SIN3B; NR1H2; BATF3; CCNA2; RUVBL1; MYCL; DEAF1; CREB5; ZBED1; RNF10; TRIB3; ARL2BP; ZNF205; MDFI; TEAD1; VPS72; SAFB; RBM39; UBE2L3; SCMH1; WIZ; RXRG; FUBP1; PRDM10; NFX1; ABT1; BRD8; BRD4; PBXIP1; NFE2L2; ZNF84; ETV4; ZIC3; NRIP1; ZNF189; TLE1; SMARCD2; ACTL6A; ZNF146; REXO4; RCOR1; LIN28A; TAF4; HDAC1; FOS; SRCAP; HOXD10; TOX4; CERS6; ERBB4; MTF2; KAT6A; PSMD9; JUP; ZBTB20; ASH2L; SF1; ETS1; ZNF140; ZNF248; PARP1; CREB3; BRD3; NANOG; CITED2; NR0B2; ZNF468; NR4A1; SUMO1; TRRAP; CDK2; AR; SETDB1; MBD4; BANP; EGR1; CENPF; SMAD5; PSPC1; UBE2I; ZMIZ1; MLXIPL; SALL2; TRIM28; NFKB2; ZMYND8; ZFPM2; DRAP1; APEX1; TAF11; ZEB1; TBX2; IRF1; PHF20; CRK; MYCBP; HNRNPD; SMAD6; ZNF528; PNRC1; ZHX2; BRD7; SUZ12; PLAGL1; PAXBP1; ZNF432; ENO1; ERBB2; HMGA1; MEIS2; CBX6; ESR1; BRCA1; CLOCK; BCLAF1; JUNB; MED24; ZFP36L1; BNC2; SMAD1; ID2; SSBP3; PRKDC; ZKSCAN1; CEBPB; ZNF32; TFDP1; DNAJC1; TLE4; SIM2; PDLIM1; MECOM; ZNF217; ZNF331; HIRA; RUNX1; FOXF1; ELK3; TDP2; MNAT1; RUNX3; PUF60; TOX3; KDM5D; WT1; TBP; HOXB2; THAP11
Down-regulation	239	OLIG2; SMAD2; ELF5; DMRT1; IRF6; KDM5B; HOXC10; ELF4; TRPS1; WHSC1L1; IKZF3; SP140; ZNF507; PITX2; ADRB2; MDM2; TRIM22; RELB; EGR4; SOHLH2; IRF4; BATF; NLK; MKL2; STAT4; ZNF165; TFCP2L1; IKZF2; FOXE1; STAT2; ASH1L; MYT1L; SOX10; GATA3; TAF5L; PPARA; KAT7; NR2C2; SHOX; HOXC6; PGR; TRIM33; SATB1; MXD1; RNF141; HDAC4; TBL1XR1; ZBED2; ZNF770; TRIM29; CRYM; LMCD1; NFKBIB; HOXC5; ZBTB25; PKNOX2; NFATC4; MBD2; GFI1; HOXC4; ING1; YAF2; HEY2; TSC22D3; ETV6; MYT1; ZNF222; SPIB; FOXC1; ZBTB3; ZNF14; EYA2; TXNIP; CREBZF; ASCL1; CBL; HOXA1; DLX5; MAFB; PEX2; EHMT1; ZFHX4; CHD2; ZNF124; SOX5; ZNF226; KDM2A; SOX18; TAF1; PAX1; POU2AF1; KLF2; AFF2; HMGB2; BRF2; CHD7; ZKSCAN7; CREB3L1; ZBTB39; E2F2; KLF5; NR1D2; IKZF5; CREB3L2; NCOA1; PRDM1; IL16; RARB; ZBED4; RELA; USF2; WWP1; ZNF473; SKIL; GRHL2; EPAS1; BCL10; SERTAD2; STAT3; SNAI2; ZNF141; NR3C1; NR3C2; HEY1; NR1I2; ZEB2; ZIC1; ELK4; HMGB3; MECP2; ZNF329; SIX2; MAF; PBX3; BACH2; ARID4B; CUX2; THAP1; GABPA; VGLL1; NHLH1; SKI; IRX5; YBX2; STAT5A; SNIP1; TAF12; MNDA; XBP1; ZNF443; LEF1; ZFP64; ZNF267; EN1; MYCN; NR2F6; AGO2; LIMD1; HIPK3; IRF5; MNX1; PIAS2; PROX1; ABL1; SATB2; EED; ZNF274; IRF9; BLM; ZNF574; EBF2; TCF7; AATF; ATF6; FOXJ2; PIR; SIX3; PAX8; HTATIP2; POU4F1; RNF14; FOXL2; ZBTB1; MEOX1; LZTS1; BARX1; FOXG1; BIRC2; MDM4; EYA1; BTG1; ELF3; ZNF394; EGR2; CHD4; NR2F1; ZNF589; WNT4; SALL1; GLI2; NKX2-1; SSBP2; GATA2; PAX5; CBFA2T3; MEF2A; ETV5; ID1; HHEX; YAP1; SAP30; NR4A2; NFATC1; BHLHE40; TCFL5; YWHAB; PPARG; MLXIP; SMAD3; MYB; REL; HOXD3; MYBL1; CEBPG; RARA; MEF2C; ERG; IKZF1; ZNF652; HES1; STAT1; BCL11A; TBPL1; FOXO3; RORA; SSX1; FOXO1; ZBTB16; OSR2