Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56279	Mepivacaine	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	334	ZNF593; FOXM1; ARL2BP; TCEA1; CREB3; CSDE1; CCNC; XRCC6; REXO4; GCFC2; PCGF1; MDFI; TCF3; VEZF1; PTRF; PSIP1; PBX1; TFAP2A; TCEB2; HDAC3; YEATS2; ATN1; TTF1; NCOR1; ERF; WIZ; CIC; SF1; CDC5L; RBM39; MYRF; IFI16; ZSCAN2; CBFB; ZNF195; PRDM4; BAZ1B; TFDP1; CBX3; RYBP; TSC22D2; CEBPB; CIZ1; NELFB; TBX6; RBBP8; CTCF; TBL1XR1; ZSCAN12; HMGB1; LOXL2; ATF4; MED6; SREBF1; ZFP36L1; MEIS1; EDF1; WDR77; TERF1; TGFB1; CENPB; MKL1; ITGB3BP; ZHX2; KDM5C; BRD4; SAFB2; MED16; MEIS2; HIF3A; APEX1; MED23; SRCAP; TULP3; SMARCB1; TFE3; MYBBP1A; TRIM27; ACTL6A; ZNF250; ZNF232; SREBF2; RAN; ATF2; BTAF1; PSMC3; SMAD7; PMS1; TCF25; CARM1; ID3; RBFOX2; FLNA; ARID1A; HMGXB3; STAT6; TEAD4; GABPB1; ZBTB11; ZNF35; PA2G4; USP22; HOXA11; GMEB2; HOXA10; PRKDC; ZZZ3; ORC2; ZBTB17; ZNF335; DLX2; SIN3B; AR; HIPK1; SMAD4; HOXB3; APBB1; RLF; ZFP69B; WWC1; RUVBL1; MED15; HCFC1; E2F4; JUND; CALR; ZNF32; TAF6; LITAF; SCMH1; ELK1; NFIC; TAF11; RNF10; ZNF146; BRD3; SRF; RFC1; C1QBP; IKZF1; PQBP1; NR2C1; ATF7IP; ABL1; TRIB3; NOC2L; CCNA2; ESR1; POU5F1B; HSF1; NR1H2; ZNF281; RBBP4; ERCC2; CDK9; SMARCD1; MYBL2; HIF1A; TAF1A; CRK; PHF20; PPP1R13L; EP300; ZNF140; ARHGAP35; SLC2A4RG; ZNF430; SOX9; ELK3; CHD8; GLI3; COPS5; THAP10; ERCC3; SNW1; CHD9; ZNF268; KAT8; CNOT1; FUBP1; CNOT3; TRIP4; MSX1; HDAC2; COPS2; ZNF410; BRD8; ARNT2; JUN; MYCBP; GATAD2A; TFAM; TGFB1I1; CNOT6; ING4; TAF7; SUPT5H; MAML1; YBX3; REST; PSMC3IP; ZNF22; DEAF1; ZFP36L2; HINFP; HBP1; CNBP; ENO1; ATF5; PIAS4; GTF3A; ERBB2; ZEB1; HNRNPD; TRIP6; UBE3A; MED27; NFX1; ZNF12; MAZ; ZNF84; ILF2; VPS72; HOXD9; HIRA; ZNF189; RFXANK; PSMD9; SUPT6H; PMF1; TLE1; BRD7; WWTR1; DEK; RB1; HMG20A; ZNF580; UBE2L3; EMX2; HIVEP1; SMARCA4; NR0B2; MYBL1; ZNF500; INSM1; PIAS1; MED17; SIX1; POLR3C; NSD1; CUX2; NFIB; ETV4; MTA1; NUP62; EHMT2; ZBTB38; MEF2D; ZBED1; MGA; DNAJC1; PNRC1; TCF7L1; ZNF384; PARP1; SIX2; RNF138; ZKSCAN1; USP21; SPEN; RAD21; CBX5; FOXK2; EZH2; ETS2; LIN28A; ARID3B; SMAD6; ZNF512B; RBPMS; KAT6A; NRIP1; MED21; AHR; ECD; RNF4; HMGA1; CTBP1; BANP; UBE2B; NPM1; ARID5B; MNAT1; UBE2I; CDK2; HDAC1; CCNH; NFYB; SALL2; HOXB2; NKX3-1; NFATC3; ARNTL2; BIRC2; SMAD1; DMTF1; INSR; SSRP1; TRIM16; NR2F6; ATF1; ZBTB18; SMAD3; CTR9; FOXO3; CEBPD; ZMIZ1; ATF3; RUNX1; MITF; SP100; ZNF589; TCF4; TBP; BASP1; TAF10; ST18; SCAND1; WT1; IKBKAP; CENPF; SNAI2; HOXB6; THAP11
Down-regulation	258	HDAC4; EGR2; TRIM25; OLIG2; NR4A2; ZNF701; KLF5; ZNF695; ZNF711; ELF3; RELB; ING3; SMAD2; NR3C2; IKZF3; STAT2; MYT1; ZNF329; MXD1; ZNF587; ZNF443; NFKBIB; NR3C1; KAT7; ADRB2; WHSC1L1; EGR3; CEBPA; CBX7; HOXA1; TAF4B; SOX21; FOXE1; SATB1; NCOA1; CIITA; ZNF14; HIPK3; DLX4; DMRT1; ZNF460; BRWD1; NFKB2; MDM4; TXNIP; STAT5B; GFI1; RFX5; ETV1; MED1; ZNF415; NR4A3; ING2; SOHLH2; ASH1L; PPARA; MAF; PAX1; IL16; RFX2; ZNF273; OVOL1; SHOX; EGR1; GRHL2; MNDA; IKZF2; GATA3; NR1I3; ZKSCAN8; ZNF813; ZNF225; ZNF671; PRDM13; MEOX2; AFF4; LHX2; ZSCAN18; MYT1L; ZNF586; GCM1; ZFY; ZNF134; ZNF506; LZTS1; ZNF211; CERS6; ZBTB25; BCL11B; ZBTB3; ZNF331; CARF; LHX1; ZNF778; E2F2; CHD2; ZNF254; SSX1; WWP1; KDM5B; IRF6; KLF2; PITX2; ZNF665; FOXD1; PROX1; MNX1; ETV6; NKX2-1; ZNF571; NR0B1; POU3F2; ZNF253; CBL; NFE2; TLX3; SOX5; BCL10; NEUROD1; PRDM5; ZNF835; TFCP2L1; EYA2; MYB; L3MBTL1; BARX2; ZIM2; ZNF135; ZNF529; FHL5; HMGB2; DDX17; MYCN; FLI1; GABPA; SATB2; MDM2; ZNF721; BACH1; NLK; AEBP1; GATA2; ZNF117; ZNF141; TRPS1; PPARGC1A; ZNF200; PPARG; SSBP2; IKZF5; MTA2; BCL6; SP140; RHOA; TCFL5; ZNF43; IRF5; MAK; ZNF236; RNF141; TRIM24; MAFB; ZNF175; NR4A1; NFAT5; CCNT1; ZNF551; NRL; RFX7; STAT5A; BATF; TCF7; ARRB1; KLF9; DBP; IRX5; POU3F1; FOXA2; ID4; YBX2; ZNF552; POU4F1; MKL2; HOXC10; VDR; GTF2I; TOX; JUNB; ZHX3; ZBTB44; NFATC1; ZBED2; ZNF337; FOXO4; ASCL1; SPIB; FOXC1; KLF10; NR1D2; SSX3; ZBTB20; HES1; ZFP64; BARX1; HEY1; ZIC1; CDX2; BLM; XBP1; ZNF165; SMARCD3; BTG1; NKX2-2; ZEB2; KDM5D; TP63; KLF4; SOX10; NCOA2; CREM; SERTAD2; ESRRG; PLAG1; CTNNB1; TOPORS; ALX1; CBFA2T3; ZSCAN16; HOXB7; FOSB; ZNF274; SMARCA2; NCOA6; ELF5; ZNF33B; WNT4; TFAP2C; CHD7; PCGF2; MLXIP; CD3D; LEF1; TAF9B; MBD2; ZNF652; PRRX1; POU2AF1; TBX2; EHF; EED; REL; FOXN3; JUP; TSC22D1; TWIST1; HHEX; OSR2; TOX3