Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56276	Lofexidine	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	309	SMAD7; ZNF783; PNRC1; ZBTB32; ASH2L; CARM1; RFXAP; MEIS1; LPIN2; HOXD11; HAND1; TSC22D2; ZNF24; NKX2-1; ZNF768; HOXB3; PIAS3; SREBF2; TONSL; DYRK1B; PRDM13; EN2; RUNX3; TLE4; ZNF646; HSBP1; HEY2; PURA; ALX3; ZNF219; NHLH2; GCM1; TTF2; WDR77; KAT8; ZNF787; GTF2I; NFIC; IRF1; HMGXB3; ZNF536; SUPT4H1; JARID2; ZBTB11; PCGF1; DDX5; HCFC1; MED25; HMX1; NKX2-5; TRIM16; HDAC5; TBX2; POU3F2; DNAJC1; RBPMS; KMT2D; ZNF606; TAF5L; HAND2; BCL11A; TBX4; MKL1; BMI1; HEY1; SIAH2; ESR2; ZSCAN2; ZNF226; MTF1; TGFB1; HIVEP2; TAL1; SPEN; ZNF205; BAZ1B; AFF2; SOX12; ZNF83; NKX2-8; GABPB1; WHSC1L1; VEZF1; BRIP1; SP1; HOXD13; ATF1; KLF1; APBB1; PITX3; ETV7; DLX4; MTA1; ZNF212; SMAD6; ZNF227; MBD3; CCNA2; MAFK; ZNF574; ERF; ZNF155; ETV4; MAZ; DACH1; CASZ1; IKBKAP; RBPJ; HOXD10; BRD4; POU2F2; CIR1; MAFG; NR0B1; NSD1; EZH2; VDR; CEBPE; ZNF444; NFATC4; ZNF446; FOXF1; ERBB2; JUN; ENO1; KAT2A; GTF2A1; ZNF586; TSG101; ZNF267; NFKBIB; GTF2A2; OVOL2; PLAGL1; BRD2; MSL3; AES; ZNF692; HOXA3; RBFOX2; BATF3; RBL1; DLX2; SNW1; CCNC; TFE3; CDC5L; ZNF710; PA2G4; BCLAF1; ZFHX2; HIVEP3; MEF2D; GFI1B; HOXD9; BCOR; NCOR2; ZBTB38; KMT2B; TFEC; ZNF410; ZNF654; TCERG1; PITX1; CDYL; ADNP; ZFP64; ARID3B; ZNF512B; BASP1; ECD; GLI1; ZNF302; THRA; SRF; ARID3A; ZNF107; CALR; C1QBP; MDFI; ZNF337; HOXB2; MBD4; ID3; ZNF580; BRD8; CHD8; ARHGAP35; ZNF528; FOXF2; TRIM28; HDAC1; ZNF133; LITAF; HOXA10; MITF; MNT; BRCA1; POLR2A; HMG20A; ZNF711; RERE; TLE2; NFIX; BRF2; SMAD4; SRCAP; ZNF131; RRN3; NFE2L2; HMGB3; LOXL2; CEBPZ; IRF5; ACTL6A; TSC22D3; WNT4; NCOA4; SND1; MED20; KLF7; EYA2; ZMIZ2; MLXIPL; ID1; SP140L; GTF2F1; MED23; KAT6A; RNF4; ZNF146; SOX11; NR1H2; MTDH; MAX; ZBTB17; ADNP2; CNOT3; ZBED2; TRIB3; RB1; DDX17; ESRRG; E2F5; MED6; RREB1; HMGA2; POU4F1; SUPT3H; ZNF248; HOXA11; TOPORS; NFKB2; UBE2L3; KAT5; GLI2; ZNF532; SAP18; CDK7; RAD21; SSX1; CEBPA; TFDP1; CTR9; MED13; POU5F1B; MAGED1; SALL1; RYBP; ATF4; ZMYM2; TCF25; FOXD1; FOXO3; GFI1; PTTG1; PBX1; ZFHX3; SMARCA1; SUB1; TFAP2C; PLAG1; CAMTA1; ID2; FOXA2; MSX1; RNF14; KDM5B; ELF3; POU2AF1; TCF4; SHOX2; CRK; ZNF281; PFDN5; NAB1; PLAGL2; ATF3; ASCL1; BHLHE41; PMF1; TBP; FOXO4; NPAS2; KDM5D; ST18; IFI16; MECOM; LEF1
Down-regulation	314	HMGB2; USP16; KLF2; BACH1; CAMTA2; ZNF562; GATA3; CREB1; KMT2A; ZNF43; MEOX2; MLXIP; ZNF93; EDF1; PSMD9; NFAT5; ADRB2; CCNE1; FOXN3; ZNF665; ZNF195; WWTR1; RXRA; SETD3; BTG1; FOXM1; ZHX2; TCF3; CBX7; KDM5A; KLF9; PCGF2; PREB; BCL10; PAXBP1; MYF6; TULP3; IL16; KLF13; NR4A2; EGR2; RXRG; CREB3L1; BNC2; HOXC6; ZMYND11; YAP1; ZBTB20; TRPS1; NCOA3; ZNF423; TERF2; LMCD1; MED1; ATF7IP; ZNF331; MEF2A; MLLT10; FOXO1; ZNF589; AGO2; ZNF329; TOB1; MED17; EYA3; ING3; ZNF211; HOXA5; ZEB2; CEBPG; NR1H3; FOSL1; CREBZF; ZFP2; ZNF202; SUPT7L; GBX1; PRMT2; MEIS2; ETV6; ZNF14; ZNF652; PIAS1; DMTF1; NFKBIA; ZBTB24; THAP11; DDX54; TEAD1; TSC22D1; ERBB4; SNAI2; TXNIP; MECP2; ARNTL; ZFHX4; ZNF239; NFYB; KLF3; BIRC2; TFEB; DAXX; SMAD1; TP63; HDAC4; AHR; THAP7; IRF7; KLF15; PKNOX2; NR2F6; ZBTB25; STAT5B; TCF21; SAP30; ABL1; PDLIM1; URI1; ASCL3; ZZZ3; MGA; NR3C2; TBL1XR1; EHMT2; ING2; CERS6; PITX2; CAPN15; PATZ1; ARID5B; ZNF45; ZBTB16; IRF9; PMS1; TCF7L2; OSR2; SIX3; SOX21; BRWD1; TDP2; BBX; HOXA7; RFX2; PAX8; EED; STAT1; DLX5; ZNF682; ELK4; TULP4; TEAD4; TTF1; ZIC1; TCF20; MNAT1; NFRKB; ZNF629; TRIM29; RNF138; STAT5A; HDAC9; BRD7; CHD7; TAF10; CCNT1; NCOA1; HMGXB4; CTBP2; SMARCC1; SOX2; MXD4; CHD1; PHF20; IKZF5; SATB1; PTRF; PQBP1; RNF141; TRIM33; DEAF1; DDIT3; PHIP; NR2C1; EWSR1; FOS; ZNF32; EZH1; ZNF217; ZHX3; TMF1; ZNF688; TGIF1; MDM2; CDK9; MYRF; BANP; ANKRD1; ZNF8; ZNF33B; PRDM5; BRD3; CREBL2; WIZ; CSDE1; ZNF91; GATA2; HIPK3; BRPF1; TAF1; TBX3; SIN3B; ZBTB1; KLF6; AATF; FEV; KAT2B; ZFP36L2; TRAF6; ZBED1; ZNF506; ARL2BP; CIZ1; CEBPD; SFMBT1; KLF11; REXO4; GTF2IRD1; BAZ2B; PSMC3; HOXD3; SKI; BCL3; TCFL5; TLE1; SMAD3; CRY1; GATA6; FOXK2; ETS1; SCAND1; HIVEP1; BLM; OLIG2; PPARD; EGR3; ZNF200; NELFB; UBE2B; PRDM2; ELF2; NPAT; ZNF443; TFCP2; ARNT2; SPIB; TAF1D; ZEB1; MAF; ZNF611; EMX2; HOXA1; ZNF274; JAK2; ELF5; PROX1; PAX5; HHEX; RUNX1; TERF1; GTF3A; MED4; SERTAD2; NR1D2; TAF12; CLOCK; RELB; BCL11B; RNF6; MTF2; ZNF354A; TOX3; SIX1; PAX6; HMBOX1; KLF5; ZMIZ1; NRIP1; ZNF124; HOXD1; ELK3; ZNF232; BACH2; SSRP1; PIR; NR4A1; KAT6B; NFATC3; TOX; YBX3; MAFB; NR2F1; ATF5; SSBP2; BHLHE40; MYCL; VGLL4; NFATC1; HLF; PPARG; EGR1; ERG; SOX9; HOXB7; PEG3