Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56272	Granisetron	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	313	CCNC; FOXM1; ZNF593; REXO4; TFAP2A; ZFP36L1; GCFC2; PSIP1; HDAC3; TFDP1; CREB3; RAN; PRDM4; MDFI; RBBP8; KLF1; TCF3; INSR; TAF11; TCEA1; PBX1; TRIM27; ATF4; CSDE1; PSMC3; TSC22D2; CBX4; CHD8; HNRNPD; CTCF; SRCAP; ATN1; APEX1; XRCC6; CDK9; TULP3; NELFB; TGFB1; TFE3; ARL2BP; DEK; MAGED1; VEZF1; MEIS2; ARNT2; RBM39; MEIS1; TERF1; WDR77; AES; HIRA; PRKDC; IFI16; ZNF335; ZHX2; ESR1; MYBBP1A; ZNF146; HBP1; TRIP6; CIZ1; HDAC2; EDF1; ZNF84; ECD; CBX3; LOXL2; SNW1; PRDM10; SREBF2; MKL1; UBE3A; MED6; JUND; KDM5C; ATF2; HOXA10; PHF20; HSF1; THAP10; ZSCAN12; MYRF; TCF25; MED27; NOC2L; CEBPB; ZNF423; SNAPC4; TTF1; BAZ1B; WT1; ETS1; MED25; ZNF12; ABL1; ERF; COPS5; ZNF268; CARM1; C1D; TCEB2; PSMC3IP; YBX3; MED15; ZNF573; CIC; SCAND1; MED23; SMAD6; SAFB2; ZNF232; ATF3; MED16; USP22; HOXA11; TRIB3; RBFOX2; ID3; ZNF32; HMGB1; SMAD7; SF1; RUVBL1; HIPK1; ZNF611; UBE2L3; PA2G4; CDC5L; CNOT3; POU5F1B; TAF1A; NKX3-1; ZEB1; ZNF226; FLNA; CNBP; E2F4; IKBKAP; SMARCB1; PCGF1; SUMO1; CCNA2; HIF1A; THAP4; SUZ12; SOX9; SRF; CALR; BASP1; CHD9; MYCBP; CRK; ZNF140; ZZZ3; YEATS2; PAWR; ZFP36L2; RBBP4; MYBL2; TDP2; ERCC2; RFC1; EMX2; GMEB2; DEAF1; BRD8; SIX1; PAX5; UBE2B; TAF6; CRY1; ID1; ILF2; HOXD11; ZNF512B; PPP1R13L; RAD21; ZFP69B; ANKRD1; MTA1; NPM1; ZNF580; CENPB; AHR; ZNF426; NR1H4; BRD3; ERBB2; TBL1XR1; WWC1; PQBP1; SOX15; RYBP; ACTL6A; C1QBP; MYBL1; RNF138; RNF10; ZNF189; PMS1; TLE1; CNOT6; MED20; SUPT5H; KAT6A; SFPQ; NR2C1; TCF4; RUNX1; MEF2D; HMGXB3; ZNF239; CNOT1; PBX2; DNAJC2; HIC2; ARID5B; ETS2; PRDM14; NCOR1; BTF3; PAX6; PTRF; ITGB3BP; POLR3C; GTF2IRD1; SALL2; ZNF91; HOXB13; SP140L; CNOT2; RBM14; LYL1; HES1; SMARCA4; KAT6B; SALL1; NRIP1; CTBP1; GABPB1; SIX2; PARP1; GATAD2A; TAF7; MAZ; MED17; BCLAF1; CDK2; SMAD4; SREBF1; HDGF; LIN28A; SP3; STAT6; FUBP1; TCF7L1; RB1; DLX2; ATF1; PSMD9; HOXD10; ZNF44; TEAD4; ZNF544; COPS2; DMTF1; DDIT3; TP53; AR; SUPT3H; CEBPD; ZNF217; KLF6; HDAC1; BIRC2; CCNH; TCF7L2; NR2F6; ZBED1; BNC2; JUN; MED21; ZNF160; ZNF432; NR2F2; BRD4; CARHSP1; CTR9; HMGA1; ARID1A; CENPF; TGIF1; ARNTL2; ID2; TFDP2; ZMYND8; ZNF589; NR1H2; MNAT1; CBX5; FOXF2; AFF1; SMAD1; FOXO3; NFATC3; PBX3; MECOM; TBP; PDLIM1; CITED2; SSBP2; SMAD3; ATF5
Down-regulation	263	HMG20B; TRIM25; RFX5; EGR2; HDAC4; NFAT5; KLF9; ZNF672; LZTS1; ASH1L; ZNF506; OLIG2; NKX2-1; NR3C1; IRF4; BATF; ZNF443; ETV1; TAF1; NFKB2; HOXC6; ZNF14; RFX7; ZNF286A; STAT5B; KDM5B; GFI1; BCL11B; ZNF253; ETV6; RELB; ADRB2; CEBPA; IL16; STAT2; MDM4; BRWD1; NLK; TADA2A; MYT1; PROX1; HEY1; LHX1; MEN1; ZKSCAN8; EGR3; WHSC1L1; NFIL3; ING3; EGR1; SMAD2; NR1H3; PURA; MED1; MDM2; ATF7; ZNF556; NFKBIB; KAT7; ALX1; SOX10; ZBTB25; MYCN; ZNF695; DBP; SATB1; MYT1L; ZNF211; MAF; MNX1; AFF4; HIPK3; NCOA1; ELF5; GTF2I; ZNF460; TAF4B; ZBTB32; NFATC1; MAFB; ZNF701; HOXA1; ZNF586; ZFY; MKL2; ASCL1; PRDM13; STAT5A; NEUROD1; GATA3; NR1I3; IKZF2; BCL3; ZNF493; NR1D2; TXNIP; CIITA; REPIN1; DMRT1; KLF5; SOHLH2; JARID2; ELF3; CERS6; FOXO4; XBP1; ZNF34; NR4A2; YBX2; SSX1; STAT4; NR3C2; SKI; ZIM2; BACH1; RFX2; IRX5; NRF1; TFAP2B; ZNF671; IKZF5; ZBTB44; EYA2; RBL2; BRPF1; HOXC10; POU3F2; CARF; ZNF571; CREB3L2; HR; MECP2; ZBTB39; CHD7; HOXA5; PAX1; RHOA; LHX2; BMI1; ZNF415; OVOL1; CBL; TLX3; TCFL5; GATA2; GRHL2; POU3F1; IRF6; CITED1; ZNF529; HOXC13; CDX2; BLM; ID4; PKNOX1; ZNF236; PRDM1; RSF1; SP1; ZNF124; ZNF711; PPARG; E2F2; GATA4; ZSCAN32; HIVEP2; CD3D; ZNF329; EHF; ZNF337; ZNF813; NFKB1; ARRB1; VGLL1; CCNT1; PLAG1; ZNF273; CBFA2T2; EZH1; PITX2; MXD4; FOXE1; MEOX1; MXD1; ESRRG; IRF5; TRPS1; SATB2; SMAD5; DLX4; SP140; TAF1D; ZBTB20; AEBP1; CAMTA1; WWP1; EN2; MLLT10; ZBTB38; SOX5; BCL6; NR0B1; ZNF267; ZMYND11; DDX17; NCOA6; TBX2; ZSCAN16; ZNF107; SERTAD2; STAT3; SIRT7; ING2; MLXIP; CREBZF; GLI2; CDK8; FOXA2; HMGA2; TSC22D3; ZNF274; ZBTB18; NR4A3; CBX7; POU4F1; KDM5D; TSC22D1; CREM; REL; PIR; TP63; LIMD1; ZNF652; HOXB7; BTG1; EED; FOXA1; SNAI2; CHD3; RNF14; MBD2; MYB; HLF; BAZ1A; NR2F1; ZBED2; MEOX2; TRIM24; FOXD1; ELF1; FOSB; MXI1; FOXC1; SOX4; IKZF1; FOXN3; RORA; VDR; FOXF1; STAT1; HOXB6; ZEB2; TOX3