Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56269	Duloxetine	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	331	CCNC; ZBTB11; ZNF593; VEZF1; PSIP1; CDC5L; TCEA1; REXO4; TCEB2; SREBF2; TFAP2A; ZSCAN12; TRIM27; MDFI; CTCF; CSDE1; HDAC3; RBFOX2; BAZ1B; JUND; ZNF140; NELFB; ARL2BP; PCGF1; BRD8; TTF1; CBX3; CREB3; ZSCAN2; ZNF771; XRCC6; TFDP1; ATF4; ATF2; MEIS1; ATN1; APEX1; MED16; LOXL2; MED6; ZNF430; NCOR1; ZNF544; PA2G4; HOXC6; ZNF268; ZNF146; TOB1; NFIC; RBM39; TAF7; MED23; MAP3K10; MKL1; HBP1; PRDM4; GCFC2; BRD4; CENPB; CRY1; SAFB2; NR2C1; EDF1; PHF20; STAT6; RAN; TSC22D2; BAZ1A; HIF3A; SF1; CIZ1; HCFC1; TERF1; ZNF573; RFC1; PRRX2; ZNF32; HIPK1; KAT8; ELK1; ZNF586; NPM1; MED17; USP22; SIN3B; CNOT1; ZNF83; ZBTB7A; FOXM1; CNBP; TAF11; MYCBP; HOXA10; ZBTB17; ZHX2; SUMO1; E2F1; MED27; SIM1; AES; NUP62; ZNF266; SCAND1; MED25; IFI16; HNRNPD; WWC1; CHD9; RAD21; DEK; GABPB1; ZFP36L1; RLF; SMAD4; SMARCB1; TULP3; ID3; ZNF189; CNOT6; IKZF1; ZNF232; CCNA2; CRK; C1D; RUVBL1; ZFHX2; HIRA; CDK9; CHD8; CARM1; COPS5; ATF7IP; SRCAP; MED15; ARNT2; SMARCE1; NKX3-1; KDM5C; ERBB2; SMARCA5; BTF3; APBB1; EVX1; NOC2L; TRIP4; SAFB; HIF1A; ABL1; SREBF1; BASP1; SUZ12; SP140L; ZNF84; ZNF426; EWSR1; ZNF91; HMGB1; RNF4; SNAPC4; MEIS2; BCLAF1; HOXA11; E2F4; HMG20A; ZKSCAN1; DDX5; SRF; PBX3; MED20; KLF6; ESR1; PFDN5; SNW1; COPS2; TCF25; NONO; HDGF; HDAC2; TCF3; IKBKAP; YBX3; RBM14; PBX1; ERF; RUNX1; CARHSP1; UBE3A; ZNF419; CBFB; PRKDC; TRIB3; TLE1; MAZ; IRF3; HDAC5; CNOT3; PTRF; TCF12; NFRKB; SP110; CENPF; PRDM10; RNF138; RNF10; CTBP2; ITGB3BP; MSC; PQBP1; ZNF410; RYBP; NFE2L2; HOXB13; ETS1; CALR; TGFB1; SMARCD1; ENO1; RFXANK; ZNF580; GATAD2A; MYBL2; ARID1A; ATF3; MEF2D; PSMD9; ATF5; ZNF12; SP100; BRD2; SPEN; PMS1; SFPQ; TSG101; SMARCA4; HDAC1; ZNF611; CBX4; TAF6; GATA2; PSMC3; TRIM16; SMAD1; POU5F1B; CCNH; ILF2; RBBP8; BRD3; NFE2L1; NAB1; MLXIPL; NFIB; AR; ZBED1; PARP1; SIX2; CBX5; ZZZ3; PBRM1; ZFP36L2; NPAT; UBE2B; PTTG1; CLOCK; INSM1; SMARCC2; MSX1; ZNF512B; HTATIP2; MGA; FLNA; AFF1; SUPT5H; DNAJC1; ELK3; ARNTL2; DR1; JUN; NR2F6; KLF2; TBP; RB1; TCERG1; NCOA4; ZNF281; CSDC2; TGIF1; ATF1; ECD; KAT6A; SSRP1; ARID5B; PAWR; ZNF432; SIX1; LITAF; WT1; DLX2; PHIP; AHR; SUPT3H; TEAD4; ACTL6A; INSR; NRIP1; BRD7; TRIP6; GTF2IRD1; YWHAB; MED21; CTR9; SOX9; DNAJC2; TCF7L2; GTF3A; PMF1; HOXB2; BIRC2; MNAT1; CTBP1; NR1H2; WWTR1; ZEB1; CREB3L1; LMCD1; MTF2; FOXO3; FOSB; PDLIM1; GATA6; EMX2; HMGN3
Down-regulation	249	EGR2; DMRT1; RELB; HDAC4; MDM2; KLF5; GRHL2; IKZF2; NR3C1; ZNF286A; HOXA1; ZNF695; SOX30; IRF6; PAX4; EGR3; ZNF157; TRIM25; IKZF3; NFKB2; ZNF492; CIITA; ING3; TRPS1; ZNF273; ZNF254; ZNF711; NCOA1; PPARA; ZNF571; GFI1; WWP1; SOHLH2; ADRB2; BRWD1; NR4A2; CAMTA2; ZNF443; ZBTB25; ZNF460; CBX7; ZBTB32; ETV1; CARF; ZNF236; ZNF141; MAF; BRDT; OLIG2; RARB; L3MBTL1; SMAD2; ZNF493; WHSC1L1; FOXE1; LHX1; RFX5; CEBPA; ZKSCAN8; GATA3; E2F2; SATB1; KAT7; KDM5B; MKL2; ELF3; ZBTB3; ASH1L; MXD1; EGR1; ZNF208; MDM4; TP63; ZNF675; STAT2; NFKBIB; SSBP2; KLF9; ID4; MYT1L; ZFY; HIPK3; ZNF225; EHMT1; TAF4B; NR3C2; EYA3; STAT5B; SP1; ZNF770; HNF4G; ZNF701; MYCN; NR2C2; ZNF165; DLX4; BCL11B; CHD2; HOXA2; ZNF813; SOX10; ARRB1; IL16; EGR4; FHL5; TAF1; TXNIP; STAT5A; MNX1; GTF2I; PRDM5; EYA2; NR5A2; PPARG; MYB; MNDA; YBX2; AFF4; SOX17; ZBTB39; NR1D2; TCFL5; PRDM1; NFAT5; POU2AF1; POU3F1; TLE2; ZNF506; CBL; ZNF552; LZTS1; MEOX2; EBF2; ZKSCAN5; RNF141; BACH1; KLF12; ZNF329; TRIM22; PITX2; NFE2; BCL6; STAT3; ELF5; NR1H3; MAFB; KLF3; NR0B1; MEOX1; ZNF135; NKX2-1; SIX3; FOXA2; MAK; ZNF117; CREM; JARID2; SMARCD3; BARX1; BNC1; ZBTB6; SOX5; GABPA; CDX2; ZNF415; CBFA2T3; TBX2; RARG; PIAS2; ZHX3; CREBZF; MLLT10; ZNF835; NEUROD1; HES1; ZIC1; RHOA; HIVEP2; FOXD1; PPARGC1A; TFEC; SP140; DLX5; IKZF5; IRX4; FOXC1; ZNF337; ZNF107; ZNF124; ERBB4; NR4A3; IRX5; SMAD5; HIC2; FOSL2; OSR2; ZSCAN16; PLAG1; SSX1; ELK4; NFIL3; HEY1; E2F8; HHEX; EP400; RERE; ING2; HDAC9; ESRRG; EHF; TFCP2L1; BHLHE41; BACH2; TCF21; CCNE1; HOXC10; TFAP2C; MECOM; TCF7; NANOG; ZBED2; KDM5D; REL; TAF9B; JUNB; MEF2C; ZNF423; ZEB2; EPAS1; BCL11A; HMGB2; FOXF1; MLXIP; POU4F1; CAMTA1; KLF10; ZBTB16; NR2F1; KLF11; HLF; DACH1; FOXO4; NR4A1; TSC22D1; NFATC1; ZNF331; AEBP1; TWIST1; HOXB7