Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56266	Dexchlorpheniramine	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	279	HIPK1; TCEB2; JUND; ZNF593; MEIS1; FOXM1; MDFI; ARL2BP; TAL1; E2F2; TCEA1; PRDM4; BRIP1; TRIM22; NR0B2; DNAJC2; MED16; PSIP1; TERF1; ZFP36L1; ETS2; TFAP2A; GATA6; TGFB1; TTF2; BAZ1B; MECOM; SUB1; ZNF468; VEZF1; ZIC3; AFF1; SNW1; ARRB1; ACTL6A; KLF1; SOX13; SMARCD1; PCGF1; DDX54; PTRF; RFXANK; HMGXB3; ZBTB17; ETV4; CHD8; PIR; ZNF408; GABPB1; HDAC1; RFC1; SMARCA4; PRKDC; TGIF1; TFE3; CSDE1; PLAGL1; TRIP6; HOXB3; ZNF771; TRAK1; RBBP8; RREB1; GMEB2; CARM1; PEX14; CDC5L; CTCF; WDR77; LZTR1; IKBKAP; NPM1; CDYL; SMARCB1; ZNF345; ZNF250; ZSCAN9; ZNF268; CERS4; BRD8; SIN3B; TFDP1; TAF11; ASH2L; MKL1; HDAC2; IRF1; CNOT3; HOXA10; SREBF1; SETD2; ATF2; RBFOX2; POU5F1B; RUVBL2; MED6; TAF6L; E2F4; SUPT5H; MTA1; NSD1; TCF4; SOX15; HOXA11; GON4L; NOC2L; CALR; ZNF580; ABL1; BHLHE40; XRCC6; HLX; BRF2; MED25; RAN; PCGF3; IFI16; ZSCAN31; ZMYND8; SOX17; AHR; SMAD7; WWC1; HMG20A; NR1H2; ZNF335; TULP3; ZNF195; PPARD; MEIS2; STAT6; FOXO3; SPDEF; HOXB2; TRIP4; FOS; ATF5; KDM5C; C1D; HSBP1; SRF; MED23; REPIN1; ADNP; ARID5A; PIAS4; BPTF; ZFP69B; CREB3; DNMT3B; ABT1; RUVBL1; NKX3-1; APEX1; APBB1; ZNF536; MYRF; ADNP2; BRD4; VGLL4; TCF7L1; CTBP1; TRIM28; PHF8; IRF3; ARID1A; TCF25; RERE; ELK3; HSF1; CCDC59; CENPB; SP100; DDX5; HOXB5; ELF4; MAGED1; TAF4; CCNC; SP110; FLI1; MEF2D; TOPORS; NELFB; TRIB3; ZSCAN5A; PMF1; TLE1; ATF4; PTTG1; TAF6; ZNF512B; GTF2A2; CTR9; SUZ12; TSG101; JUN; MED24; CITED1; BTF3; COPS5; EMX2; NR5A2; UBE2I; WT1; ZNF426; SOX9; SP2; TCERG1; TEAD4; RBBP7; GLI2; ECD; LOXL2; SOX4; CHD4; HIVEP1; HAND1; YBX3; RBPMS; VPS72; MBD4; NONO; TRIM32; XBP1; ELF3; NUP62; RBM14; PA2G4; ZNF146; ERBB2; NRIP1; HES1; ZFP36L2; CDK7; RNF10; PFDN5; GTF2IRD1; BHLHE41; CREG1; HOXD1; ZNF423; TBL1X; MGA; RBPJ; ILF2; BCL3; HMGXB4; BRCA1; NR1D2; ZNF22; INSR; CNOT2; HHEX; ST18; ZNF232; NRBF2; SMARCA1; FUBP1; EHF; SALL2; TBX2; ZNF12; HOXB6; RUNX1; FOXO1; PPARG; RUNX3; BASP1; BNC2; RYBP; CCNA2; MTF2; ENO1; CENPF; NR2F6; ZNF589; MSX1; TOX3
Down-regulation	259	HDAC4; KLF5; OLIG2; HOXC10; HOXC6; NCOA1; STAT2; CREB1; ZNF443; ZNF586; ZNF273; MAF; TBX3; BACH1; BCL11B; HR; NR4A2; MXD1; ING2; ING1; IKZF5; BCL10; RXRA; GATA3; SMAD2; MLX; HOXA1; RNF141; CDK8; SNAI1; ZNF253; MECP2; ETV1; LHX1; ADRB2; ING3; NR2C2; TRPS1; LZTS1; ZNF93; KMT5A; KLF9; URI1; ASH1L; TERF2; PKNOX2; CREBZF; ZNF506; EGR1; ATF7IP; TCF7; NFKB2; MYT1L; PREB; ZNF654; ZNF665; FOXE1; TLX3; PKNOX1; NEUROG1; KDM5B; TAF5; ZNF134; SATB1; NKX3-2; FOSL2; FOXO4; ZBED2; PURA; TRIM29; BRWD1; MEF2A; ZBTB25; POU3F2; BAZ2B; CNBP; MAFB; NR1I3; ZNF200; NRF1; ZNF132; DLX4; IKZF2; USF2; CD3D; ZBTB18; PPARA; ZNF562; LIMD1; TCFL5; VDR; DACH1; E2F6; NR3C1; KMT2A; CDX2; POU3F1; STAT5B; BTG1; MXI1; ZNF14; SOX21; PATZ1; ZSCAN18; BRD7; EYA2; MBD2; EED; SHOX; HMGA2; MNDA; DLX5; TLE2; POU2F3; IL16; ZNF460; KLF12; TAF12; NEUROD1; NFKBIB; NFKB1; TAF1; HTATIP2; SAP30; CAMTA2; NHLH1; ZNF276; TP63; SSBP2; ZFHX4; ARID4B; AGO2; GATA2; MYCN; YAF2; ZNF267; HDAC9; REL; CUX2; BCL11A; DBP; ZNF331; HOXC4; FOXG1; ZNF467; ZNF222; ZHX3; RORA; CREB5; GABPA; NPAT; PROX1; ZIC1; ID4; THAP11; MKL2; BATF; ZNF813; TRIM16; ZNF211; ZNF329; PEX2; YAP1; CHD7; MXD4; MEOX1; CREB3L2; HOXC13; SIX3; FEV; EGR2; RNF14; EGR3; PSPC1; MDM4; NRL; BTAF1; HIVEP2; STAT3; ZNF160; CRK; WNT4; NR3C2; KLF7; ZNF415; RCOR3; NFIL3; ZNF430; ZBTB14; FOXD1; VGLL1; IRX5; FOSB; SMARCD3; BNC1; RFX5; BMI1; HOXA5; SERTAD2; SATB2; IRF6; BIRC2; EZH1; NR1I2; ZBTB43; IKZF1; ZMIZ2; GFI1; HOXD3; ZNF264; ZMYM2; ZNF721; BCL6; TXNIP; NFIB; NCOA6; SMAD3; LEF1; TRAF6; POU4F1; ZEB2; BANP; FOXN3; PLAG1; NR0B1; CEBPG; HMGB3; NKX2-2; NAB1; MAX; KLF11; HEY1; ZNF91; MTDH; HDAC6; AATF; DDIT3; CBFA2T3; SUPT3H; BRD3; NFATC4; ID2; FOXC1; ZHX2; ATF1; KLF2; PRRX1; BBX; KDM5D; RELB; GTF3A; ZKSCAN1; HMBOX1; ARID5B; TAF10; MYB; SMAD1; POU2AF1; SPEN