Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56260	Ubenimex	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	325	TBL1XR1; KDM5C; GMEB1; TAL1; FOXL2; ARID1A; DLX5; JUND; UBTF; ZBTB20; HEY2; ARID4A; ESR1; OVOL2; NCOA1; TFEC; DBP; MAF; EYA2; TCF3; TP73; SIAH2; RCOR1; SIRT2; MXD1; ELK4; TSHZ2; NR1I3; MYCL; HDAC7; CSDE1; BATF3; GCM1; CTCF; TCF15; WWTR1; TSC22D2; HNF4G; PEG3; ZNF593; MNDA; TBL1X; ZBTB18; TRIM27; ZNF226; HSBP1; MED16; TAF1; RAX; MSX1; MED23; MYRF; ZBTB38; CALR; NFIL3; SMARCB1; ERF; WNT4; ZNF184; NFYA; POLR2A; C1D; BATF; PLAGL1; NR5A1; ZNF695; TSC22D4; RFC1; ZFHX3; TCEA1; ZBTB7A; CCNC; PBX2; EVX1; NR0B2; ZNF75D; DR1; RUVBL2; ARL2BP; ZNF529; HIPK3; TAF6L; VEZF1; ARHGAP35; GCFC2; MTA2; PRRX2; LZTR1; ABL1; PIAS3; ZHX2; IRF2; TFAP2A; NFATC4; ZNF576; SPEN; HDGF; ZFP30; TRIM28; CCNT1; PRDM12; GABPB1; SP2; MXI1; ZNF83; VDR; ST18; CEBPE; KAT6B; CNOT1; TCF4; TFDP1; HCFC1; SREBF1; PITX1; ABT1; NFIB; INSM1; POU4F1; HNRNPD; GTF2I; ZNF571; NR1H2; EHF; NUP62; ATF1; ZBTB17; ZNF556; ZSCAN9; PHIP; FOXO3; CDK2; KLF7; ZNF227; MLXIPL; SHOX2; CBX7; TMF1; MXD4; GATA4; ATN1; PRDM13; MNAT1; NFKBIB; NCOA3; ZFPM2; YEATS4; GLI3; RING1; PCGF3; NR2F1; CHD1; FOXJ1; ZMYND11; CREG1; EPAS1; AR; BRD2; PFDN5; ING2; CBX5; RBBP5; WT1; SP140; PRKDC; EN2; MED6; KMT5A; ZNF10; ZNF143; GFI1B; FOXO1; CCNA2; CDIP1; PAX8; RNF14; SP1; ZNF180; WDHD1; RBBP8; TRPS1; SOX15; PKNOX1; SAP30; ZNF76; GATA1; REL; PA2G4; RYBP; PBX1; PARP1; HR; PSMC3; HDAC6; EMX2; FOXJ2; ZNF516; HDAC1; NR1H4; ZNF835; IKZF5; TCF21; NEDD8; HOXB7; CBX6; LHX6; CENPB; ERG; SAFB; HHEX; ENY2; PCGF1; HMGXB4; ZBED2; CNOT6; TAF11; SETD3; CSDC2; PRDM10; MGA; ATF5; RORC; GABPA; FOS; TAF9B; ZNF580; ZZZ3; FOSL2; RBBP4; FOXG1; ZMYM2; PBRM1; USP21; BRD7; TFCP2L1; CCNE1; TDP2; TRIP4; RB1; ZNF536; ZNF165; CUX1; WWP1; ZMYND8; CRK; CLOCK; BAZ2A; ARNTL; NR2F6; CREB3L2; BAZ2B; RNF10; HOXB5; TLE1; ZNF410; MED15; TCF7L2; DAXX; HDAC4; TFCP2; TOPORS; MAZ; NRIP1; NAB1; CAMTA1; SERTAD2; GATAD2A; NRBF2; ZNF224; PSPC1; JUP; PSMD9; IRF8; CHD9; PEX2; NHLH2; STAT5B; ARID4B; CTNNB1; SPDEF; MED24; HLTF; BLZF1; ILF2; ZNF331; SUPT5H; HOXA5; SUB1; ERBB2; HOXB6; BBX; MTF2; SOX17; TRIB3; EN1; BAZ1A; CNOT3; ZNF124; SMARCA2; HMBOX1; ZFP36L1; NFAT5; VPS72; ID4; HOXB2; TP63; ENO1; PBXIP1; HMGN3; CITED2; ETS1; BTG1; GATA6; TFDP2; KAT2B; ELF5; ZNF589; BHLHE41; SSBP2; HMGB3; ZEB1; MAGED1; SMARCA1; ADRB2; ID2
Down-regulation	329	RFX5; CRYM; ZNF263; TRIM22; SMAD7; MEN1; ZNF606; HOXB13; PCGF2; ZNF202; REPIN1; PPRC1; MLX; GTF2F1; ZNF85; ZNF79; TFAM; LZTS1; MKL2; KLF2; RBPMS; DEAF1; KAT2A; SMAD6; TSC22D3; BLM; ZNF248; KDM5D; HCFC2; NR4A1; EGR2; NR2C2; PTTG1; STAT3; KLF4; TAF9; POU2AF1; NR1H3; TAF7; PBX3; ITGB3BP; NR3C1; PRMT2; ARID5A; UBP1; MAFF; BPTF; THAP10; NFKB2; ZNF423; ZNF350; HOXC10; ZNF813; ZNF134; SNAPC4; ZKSCAN7; HOXC11; BTAF1; PIAS2; THAP4; HNF1B; ZNF200; MEOX2; ZNF211; EGR1; IRF1; HMGXB3; E2F6; NKX2-1; ZBED1; RELA; ZNF329; FOXI1; PRRX1; KLF5; ZNF217; SCAND1; ALX1; TGIF2; ZNF215; PPARD; MMS19; TULP2; ZNF672; PITX2; HLX; TFDP3; SLC2A4RG; ZNF208; DMTF1; ESRRA; FOXO4; KDM4A; NANOG; MYOG; AEBP1; PRPF6; ZNF12; ARID5B; BRPF1; ZFY; GRHL2; GTF2IRD1; DLX4; LIN28A; ZNF33B; NKRF; SATB2; CITED1; LDB1; SIX3; KAT8; RUNX1; TRAK1; ZNF337; DLX2; EGR3; PRDM1; ZNF587; ZIC3; HOXA10; CD3D; ADNP; ARRB1; CREBZF; CDX1; TCF7; BIRC2; NR0B1; SMARCD2; PLAGL2; TRIM32; RNF2; ZNF384; ASH2L; SUPT3H; TULP3; ZNF500; ZNF764; CDK9; ZMIZ1; HMGA2; SMARCC1; CEBPA; ZNF710; SIM2; ZNF93; KDM2A; RXRA; SMAD2; ZNF669; TBX2; HOXD11; SOX12; MED13; SALL2; LEF1; STAT1; PSMC3IP; EP400; CRY1; HES1; HDAC9; ZNF544; ZNF235; HOXC13; CREBL2; VGLL4; SETDB1; KLF13; ZBTB1; ZNF552; THRB; ZNF16; TSG101; SUMO1; FOXF2; DNAJC1; PRDM14; ZNF7; SMARCE1; TAF4B; TRAF6; CBFA2T2; SFMBT1; WWC1; HMGA1; MNT; CBX4; NKX3-1; PHF20; MYT1; EZH2; THAP11; CDX2; TGFB1I1; ANKRD1; TEAD1; ZNF586; SOX10; BRWD1; NFRKB; ZBTB25; TWIST1; ZBTB43; SMAD5; STAT6; TFEB; SAP130; RARA; MEIS2; ZNF419; ZNF273; NLK; HDAC3; ETV4; LITAF; IRF3; HOXC6; FOXA1; GFI1; NPAT; ID1; BRCA1; ZNF266; NFIC; ZNF131; SOX4; MAML1; TBPL1; NR4A3; TTF2; MBD4; TDRD3; ZNF444; HEY1; SALL1; ELK3; ZBTB14; ZNF22; ZNF394; MAFG; ZNF574; ZFP36L2; RORA; CREB3L1; BNC1; LMCD1; ZNF652; ID3; MED17; ZNF654; TCFL5; ETV1; CTBP2; IKZF1; UBE2I; SOX2; NFIX; ERBB4; BRD4; TRIM24; XBP1; ING3; KLF10; HAND1; RNF111; ZFP64; ZNF551; ZNF646; NR4A2; NPM1; ECD; MEOX1; SOX5; ATF6; ZBTB16; ZNF512B; BANP; ZNF532; FOXE1; TBX3; SUZ12; KAT6A; PAXBP1; FOXF1; NR3C2; ZNF611; KLF9; NFKBIA; SMAD4; BRD8; HIVEP1; SUPT6H; SMARCA4; DNMT3B; USP22; NFE2L2; MYCN; IRX5; ETV5; BACH2; YBX3; NCOR2; ZSCAN18; SSX1; MAFB; ZIC1; MLXIP; RELB; CEBPZ; SMAD1; EYA1; E2F2; MTA1; FOSB; SIX2; ZNF232; FOXJ3; ZNF91; ATF3; PPARG; ZKSCAN1; BCL11A; TSC22D1; SUV39H1; MEF2C; MECOM; SNAI2