Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56259	Dihydrexidine	GSE92742	HA1E	Human	6h	10uM	EID0283

Response Information :

Types	Number	Response transcription factors
Up-regulation	335	FOXM1; CCNC; PSIP1; CDC5L; FOXP3; WIZ; BAZ1B; REXO4; TSC22D2; PRDM4; HIPK1; ZNF146; NELFB; TTF1; TFAP2A; TAF11; SREBF2; RNF10; PHF20; TRIP6; NOC2L; GATAD2A; DNMT3B; TRIP4; RBPJ; CARM1; ZSCAN12; CTCF; RBBP8; CRY1; TAF6; MED16; MKL1; MDFI; MED24; HTATIP2; APEX1; BRD8; GLI3; ARNTL2; GTF2A1; THAP10; YBX3; CSDE1; TRIM27; CHD8; HDAC5; TCF12; ELK1; IKZF1; EZH2; ABL1; TRIM16; POU5F1B; MED25; RBM14; BATF3; NSD1; NUP62; ZNF302; SIX2; IKBKAP; HDAC2; ZNF268; NONO; TFE3; MSX1; HCFC1; TCF25; NFIC; ZFHX2; HDAC3; HIVEP1; KLF6; MEIS2; HOXA10; CCNA2; CDK2; SIN3B; ZNF783; GABPB1; PNRC1; NR2C1; TUB; ZNF410; NKX3-1; MYBBP1A; HBP1; CNOT6; XRCC6; MED15; HOXB13; LITAF; ZNF335; HIF3A; ECD; KAT6A; MYCBP; DNAJC2; ATF2; UBE2L3; AFF1; CTBP1; MBD3; ASXL1; SMARCA4; RNF4; CIZ1; ZNF573; SMARCE1; INSM1; SMAD4; ATF4; RBFOX2; EHMT2; MAP3K10; CD3D; KAT8; ZNF586; MEIS1; BTAF1; UIMC1; RUVBL1; TBX10; MED20; HIVEP3; HOXC6; BRD4; HIRA; ZNF24; ZNF468; SPEN; BRD3; INSR; ZBTB11; ZNF384; ATN1; HMG20A; NFIL3; ARL2BP; HMGXB3; SNW1; VEZF1; ZNF76; GTF2A2; PAX6; MED6; PCGF1; USF2; RBBP4; HOXB3; REPIN1; BPTF; PLAGL1; HINFP; ZNF32; TRRAP; ARID3B; SF1; CTR9; ABT1; BASP1; CREB3; GCFC2; UBE3A; PPP1R13L; HAND1; SMAD7; WDR77; KDM2A; TBL1XR1; HLTF; CDK9; ARNT; STAT6; SAFB2; ARHGAP35; ENO1; NRIP1; ADNP2; ZNF202; RLF; DNAJC1; JUND; SMARCD1; RBM39; ETS2; ZNF646; IFI16; NCOR2; TCERG1; ZNF189; HSF1; ZNF593; RAD21; COPS2; SUZ12; MED23; MED27; DRAP1; MYCL; ITGB3BP; CRK; MLX; ZNF22; HOXA7; KLF7; ACTL6A; RAN; WWC1; TTF2; MED21; ERBB2; ETS1; TRIM32; ZNF500; ZNF544; TERF1; PSMD9; FLNA; HDGF; NFE2L2; NR2F2; NFIB; LOXL2; MGA; CHD9; SRCAP; SRF; ZNF232; MAX; NCOR1; NR0B2; HLX; PEX14; DNMT1; PTTG1; C1QBP; JARID2; SMARCD2; SCMH1; HNRNPD; PARP1; EDF1; ZNF140; CDK7; PA2G4; TSG101; CNOT3; SUPT3H; RUNX1; NPM1; ARID1A; TAF7; TDP2; RNF138; IRF1; PBX3; DR1; KAT5; CEBPB; BRD2; PHF2; DEK; TULP3; BCLAF1; BTF3; ZBTB18; SOX4; SND1; ZNF266; ZNF304; ID2; RYBP; CBFB; AHR; FOXA1; HMGN3; MTA1; ZNF611; MAZ; CBX3; CCNH; KLF4; SIAH2; BHLHE40; NCOA4; ELK3; NR1H2; SREBF1; MED17; FOXF2; BAZ1A; ATF1; VPS72; TFEB; ZNF12; PRKDC; RB1; ATF3; TAF10; HOXB2; PMF1; MITF; CCDC59; SIX1; TFDP1; ZEB1; ZNF91; ID3; CREG1; ZFP36L1; BIRC2; HMGA1; TCF7L2; CEBPG; TFDP2; TBP; ATF5; MYBL1; FOS; FOXO3; BRCA1; PIR; MNAT1; HDAC1; RUNX3; TCF4; ZFP36L2; FOXC1; CENPF; ARID4B; TBX3; SMARCA1; EMX2
Down-regulation	269	EGR2; HDAC4; TAF1; NR4A2; OLIG2; ZNF695; BRWD1; CARF; SOX30; PPARA; ZBTB3; ZNF701; MXD1; SOHLH2; ING3; EGR4; MAF; ZNF556; BRDT; ZNF14; ZNF157; TRPS1; CREB1; PAX4; CEBPA; NKX2-2; ZNF343; ADRB2; ZNF711; MLXIP; THAP9; SNAI1; CUX2; ASH1L; ID4; NFKB2; ZNF460; TAF4B; PROX1; CHD2; PRDM5; RELB; DMRT1; ZNF443; EGR3; IKZF3; CIITA; ZNF124; CAMTA2; LHX1; KLF3; ZNF80; KLF9; MED14; ZNF682; KDM5B; ZNF141; NFAT5; NR1D2; ETV1; SOX18; HDAC9; DLX4; SATB1; ZNF493; ELF3; SHOX; STAT2; ZNF835; ASCL2; TRIM33; GFI1; ZFY; ZNF287; SATB2; WWP1; SOX5; MEOX1; ZFP2; ZNF254; POU4F1; ZNF10; TULP1; ZNF671; HNF4G; EYA2; IL16; ZBTB25; CRYM; EHF; PKNOX1; TRIM25; WHSC1L1; ZBTB20; POU3F2; NCOA1; OVOL1; NR3C1; KLF5; MDM2; NKX2-1; GCM1; AFF4; BACH1; IRF9; KLF11; KAT7; SOX21; ZHX3; CBX7; ZNF236; EHMT1; TRIM22; BCL11B; SOX3; ZNF480; ELF4; ZNF273; ETV5; ZNF667; MECP2; EGR1; ZKSCAN8; AEBP1; LIMD1; RARG; ZNF506; TXNIP; NFATC1; CCNT1; NEUROD1; IKZF5; RCOR3; TAF9B; L3MBTL1; NR1I3; IRF4; MDM4; HIPK3; MYT1L; MED1; SSBP2; SKIL; BARX1; ZEB2; NKX3-2; MAFB; HOXA1; CDX2; FOXE1; SMAD2; PLAG1; GATA4; ZBED2; MYB; SKI; GTF2I; MEOX2; ZNF331; ZNF253; ZNF770; NR1I2; NANOG; RARB; ELF5; LMCD1; CREM; STAT4; YAF2; ZNF415; HMGB2; MNX1; ZBTB44; RERE; THAP11; NFKBIB; NCOA6; PKNOX2; PITX2; NR4A3; HOXD3; SP1; BAZ2A; LZTS1; TLE2; E2F2; TSC22D1; ZNF117; TFCP2L1; POU2AF1; TSC22D4; FOXA2; ZNF551; MXD4; REL; ELK4; TBX2; ZNF423; SMARCD3; YBX2; RFX5; TMF1; YBX1; NCOA2; ZNF165; TCFL5; DACH1; SP140; WT1; ESRRG; DBP; KLF10; ZFHX4; BBX; OSR2; PRRX1; CHD7; MEF2A; SOX17; HLF; NR1H3; TFEC; AGO2; HES1; MYCN; EPAS1; IRF6; TGIF2; TCF21; TERF2; ING2; KDM5D; GATA2; VDR; SPIB; CTBP2; SOX11; ELF1; NR4A1; TOB1; FOXO4; IRX5; PPARG; NFE2; CREB3L1; MYRF; BNC2; ERBB4; PLAGL2; FOSB; BHLHE41; ZFPM2; ASCL1; WNT4; MNDA; ZNF589; HOXD1; SSX1; ZNF652; ERG; TWIST1; FOXO1; SNAI2; NFATC4; MEF2C; JUP; NR2F1; SMAD3; PEG3