Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID55566	Cucurbitacin-i	GSE92742	HA1E	Human	6h	10uM	EID0271

Response Information :

Types	Number	Response transcription factors
Up-regulation	329	E2F2; SUV39H1; IKZF1; EGR2; ZNF586; SOX17; ZNF701; HIC2; NRBF2; OVOL1; SSX1; NR0B1; KMT5A; ZNF764; EYA3; STAT2; MXD1; ARID3B; DLX4; SP4; THRAP3; NSD1; TULP4; BRCA2; BLM; KLF3; MED14; GRHL2; PIAS3; CHD2; TCF20; ZNF695; ZNF227; MED12; ZSCAN2; ZNF696; KLF13; ZBTB43; CRYM; CTR9; NFATC1; TAF4B; ZFP36L2; ASH1L; EZH1; HAND1; TAF9B; SMARCD2; CIR1; HNF4G; PLAGL2; RCOR1; HNF4A; ZBTB39; CAMTA2; POLR2A; POU4F2; ESRRG; PRDM14; ZNF682; PRDM10; GFI1; ZXDC; RREB1; RSF1; WHSC1L1; FOXJ1; PHIP; IRF6; LIMD1; ASCL3; SHOX; BRF2; YEATS4; EGR4; PML; ZNF550; MED1; CIITA; ZNF710; ZBTB3; HOXC5; FEV; ZNF131; ZNF671; MAK; UBTF; PRDM5; HOXC4; ZNF329; RBBP5; SAFB; SMARCE1; E2F8; MSX1; TBL1XR1; ELF3; INSR; TAF1A; FOXJ3; SOX13; HNF1A; ZNF257; ZNF286A; SOX12; FOXA2; RARA; ZNF551; ZNF141; CDK7; ZNF124; DDX54; THRA; DMRT1; TBX2; NR5A2; GATA4; CREB3L1; ALX4; TFCP2L1; NFE2L1; ZSCAN18; RNF6; MDM4; SOX15; HOXA3; ZNF493; HOXA1; BAZ2A; TCERG1; TOPORS; ZNF423; CARF; MYT1L; DLX6; BRD2; ZNF34; TXNIP; WDHD1; MYB; PIR; RNF4; ZNF75D; TSC22D3; RFX2; PRRX1; RNF141; ZBTB44; PHOX2B; ZNF492; ZNF225; ZNF688; PAX7; PRDM2; SERTAD2; ZNF254; MTA2; PCGF3; ARNTL; TBX21; BATF3; PIAS1; SP2; ZFP69B; ELF5; TSG101; ZNF426; HOXC6; NCOA2; ZKSCAN5; CCNT1; ELF4; NFE2L3; CTNNB1; ERF; LZTS1; ZNF770; BAZ1B; HEY2; SND1; ARID4B; ZNF222; SKIL; HCFC1; MED23; E2F3; SRF; PHF8; FOXL2; ING2; AEBP1; WHSC1; NFE2; TAF5; ZNF711; HEYL; ZIM2; ZNF223; NKX2-2; TSC22D4; ZNF136; SIX3; IRF4; LPIN2; ZNF273; EPAS1; NFAT5; TAF1; BCLAF1; RBL1; NEUROG1; SMARCA5; SAP130; AFF1; ZNF8; SMAD5; NRF1; ERBB4; TMF1; DLX5; GATA1; HSF2; ZNF267; ZNF668; KDM4A; NEUROD1; MEN1; DDX5; ZNF516; ZNF394; TRIM24; ZNF629; MED24; NFYB; ELF2; ZNF235; TTF2; TOB1; TRRAP; ZNF665; KDM5C; REPIN1; CREBZF; KAT7; TFE3; PGR; WWP1; MAGED1; SNW1; ZNF107; ZNF215; IRF2; BHLHE41; EYA2; HSBP1; ZNF165; ZNF611; CALR; CUX2; MNT; ZNF264; SSBP3; TP63; ETV5; RLF; ZFHX3; TCF7; HIRA; HESX1; SFPQ; CHD4; ZNF195; ZNF281; ZNF226; HOXC10; TERF1; YBX2; CEBPD; ZNF835; LEF1; RRN3; TAF12; LMCD1; ADNP; VDR; DNAJC2; PEG3; ZBTB24; TAL1; HIPK1; TGIF1; IFI16; NANOG; CBX6; ZNF556; CREB3L2; MAFG; RERE; NCOA1; GATA6; RUNX3; SOHLH2; SKI; BTG1; TFCP2; MLXIP; ARID1A; HMGB2; MNDA; TCF7L1; KLF9; CEBPB; ID4; RBBP7; NR1H3; RBPMS; ASCL1; MYBL1; TWIST1; EMX2; EP300; ZMIZ1; ZNF721; MECOM; XBP1; ZNF512B; NLK; KLF10; NR1H2
Down-regulation	353	PUF60; ABL1; ATF1; PTTG1; PDLIM1; HOXB5; SMARCA4; NRIP1; ZZZ3; SP110; RFXANK; MYC; EED; GTF3A; NFKBIA; MLX; CNBP; HOXB2; TRIP6; MAF; USF2; ATF3; ZNF91; ZSCAN12; RBM39; CDK2; FHL2; ITGB3BP; MBD3; DEAF1; RNF138; EDF1; TAF11; CDYL; DNAJC1; LOXL2; ZNF133; WWC1; TLE1; UBE2L3; LDB1; ZFP36L1; IRF7; HOXB6; MED16; CRY1; NELFB; KAT5; TOX4; APEX1; NFKB1; PHF1; ZNF24; RAN; XRCC6; GLI3; SIX2; BMI1; ZNF302; COPS2; BLZF1; TEAD4; MMS19; CLOCK; TCF12; LITAF; PRPF6; TAF1D; PBX1; ABT1; TBL1X; RHOA; SREBF1; BTF3; GTF2IRD1; JUN; ECD; HOXA5; SIAH2; BNC2; ZNF35; CDK8; ZNF32; BTAF1; ATF6; HBP1; ZNF248; ERCC3; ARID5A; USP21; GMEB2; EHMT2; TAF7; ZEB1; BRCA1; PMS1; MEOX1; SMAD7; TRIM28; ING3; NPM1; TAF9; ZNF335; POLR3F; HDAC3; SMAD6; C1D; MYNN; PPRC1; ZNF692; DEK; ZNF146; MED21; PLAGL1; MEF2C; PCGF2; SIRT2; BHLHE40; ZBTB17; TLE4; ZNF202; ZNF7; BANP; CSDE1; MED6; NCOA4; MXI1; TEAD3; SETD2; ZFP37; TULP3; PBRM1; ELF1; GCFC2; CREG1; ZFP64; ZNF276; RELB; AES; TDRD3; ZNF239; PAXBP1; TAF10; NAB1; PSPC1; USP16; NUP62; ZSCAN5A; RBFOX2; SMAD1; NR2C1; MEIS2; NFKBIB; HOXB7; ILF2; SUPT7L; CBFA2T2; MITF; TCF25; PKNOX2; FLNA; CBX3; SUPT5H; BRD7; CREBL2; HOXA11; IKBKAP; GTF2F1; DLX2; TRIM16; SPDEF; GATA3; YBX3; KAT2A; NACA; ZNF250; SMARCD3; MED27; HOXB3; BRD3; SIM2; RBM14; HEY1; FOXD1; PA2G4; TCFL5; ZSCAN9; TRIM29; TSC22D1; ZBTB40; CERS4; HDGF; SOX4; NEDD8; HOXD9; PPARG; ZBTB11; HOXD10; ZNF184; UBP1; ZFX; PHF20; NHLH2; NFATC3; ST18; ZNF468; BARX1; SRCAP; ZNF274; HOXB1; THAP7; PRRX2; ZBTB18; BASP1; RBPJ; NR2F2; NR2F1; HMGB1; CREB1; CXXC1; CRTC1; KDM5B; ZNF33B; MAML1; MED7; NR0B2; RNF111; ZNF85; ATF4; HOXA10; CNOT6; ZNF266; ZNF148; WIZ; SUPT4H1; PCGF1; SMAD4; CCNC; ATF5; URI1; SSRP1; PFDN5; ZNF43; SOX11; RYBP; HHEX; HMG20B; ZBTB38; ID3; ID2; SHOX2; ZNF444; CNOT3; FOXF1; SOX9; CHD7; NFE2L2; ENY2; UBE2I; SOX2; ATF7IP; HNRNPD; SCAND1; SUB1; BCL11A; KDM5D; PBX3; HDAC1; KMT2B; EZH2; FOS; FOSB; AHR; FOXA1; ASXL1; STAT1; TCEA1; DNMT3B; SP100; ZNF84; REST; TLE2; HDAC4; PAX6; BAZ2B; CTBP1; ZNF573; SMARCB1; THAP1; THAP4; PPARGC1A; TRAK1; REL; ZNF593; ID1; FOXN3; TRIM32; KLF6; HLTF; GABPB1; IRF8; ZNF410; TOX3; WWTR1; HIVEP1; TFAP2C; ZBED2; ZSCAN31; FUBP1; RB1; SATB2; KLF7; ARID5B; TRIP4; JARID2; SUPT6H; TCF3; CD3D; YAP1; ETS2; PPP1R13L; ISL1; SP3; KAT6B; TGIF2; TCF21; JUP; PITX1; ZNF83; RFX5; PBXIP1; ZIC1; BACH2; TRPS1; PNRC1; ERBB2; SALL1; HES1; MEIS1; RORA; FOSL2; DACH1; SNAI2; INSM1; VPS72; RUNX1; ENO1; WT1; ZFPM2; BCL6; TFAP2A; THAP11; NR3C1