Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID55189	Ixazomib	GSE92742	HA1E	Human	6h	10uM	EID0269

Response Information :

Types	Number	Response transcription factors
Up-regulation	363	TCFL5; NR3C1; NFATC3; RELB; SUV39H1; KDM5A; ZNF623; IKZF1; PPARG; ZNF34; POU4F2; ZNF701; NFX1; HIC2; ZNF510; OVOL1; TCF7; ZBTB43; ADRB2; DOT1L; TAF4B; AGO2; HNF4G; ZNF835; HOXA3; STAT2; ASH1L; LPIN2; CHD2; NRBF2; SPIB; GATA2; ZNF770; NR1H2; LEF1; WHSC1L1; CDIP1; CREB3L1; ZNF117; BRWD1; EYA3; TXNIP; KMT2D; SP4; TSHZ2; NEUROG1; ZNF254; ZNF225; ZNF780B; MED14; NFAT5; ZNF671; ZNF493; THRB; ZNF696; BHLHE41; KLF13; TTF2; ZNF764; KAT7; TFCP2L1; ZNF507; HOXC5; DPF2; EGR2; MED12; ZNF550; IKZF2; DDX54; ZNF471; BACH1; WDHD1; SMAD5; ZNF682; BAZ2A; SP1; MEF2C; CBFA2T3; ZNF222; BRCA2; CEBPD; CTNNB1; ZNF814; ZBTB44; ZBTB6; HDAC11; NR1H4; ZNF674; ZNF223; TFEB; ZNF180; GFI1B; ZNF407; MAGED1; ONECUT1; ZNF107; ZNF235; TP63; PIAS1; PLAGL2; ZBTB3; ZBTB39; MAML3; TULP4; ZNF571; CIITA; UBTF; NKX2-2; ZNF710; ZNF350; ZNF695; ZFP36L2; ONECUT2; IKZF3; ARID3A; ZNF10; ZNF343; IKZF4; IRF6; NR5A2; RCOR1; ZNF334; TCEB2; ZNF492; CCNT1; ZNF81; EHMT1; HIVEP3; SKIL; TRIM24; NKX2-1; RBL1; KLF3; ZNF586; ZFY; ELF2; ZNF141; PHIP; ZNF264; ZNF214; HDAC9; HNF1A; MXD1; RREB1; NR6A1; ZNF136; DLX6; KLF8; THAP9; ZNF124; MED31; GATA1; DDIT3; ZNF556; ZNF227; ZHX2; POU6F1; TAF9B; CREB5; EP300; PCGF3; PIR; TGS1; ASCL2; POU2F2; EVX1; ZNF157; ZNF8; ZNF391; ZNF257; GATA6; TAF1; ZNF80; ZNF75D; ZNF215; ERG; LIMD1; TBX21; POU2F3; ZNF273; ZSCAN32; ZNF711; ZNF205; TSG101; TRIM33; ZNF112; DLX5; MYB; ZKSCAN7; ZNF816; SMAD9; TAL1; JAK2; ZKSCAN8; PAX4; ZSCAN2; PHOX2A; KLF2; PKNOX1; RUNX1; GABPA; TAF1A; HNF1B; PEG3; AFF1; ELF3; PGR; ISL1; TFDP2; BBX; TFEC; IRF1; FOXJ2; RBBP5; FOXA2; TCF12; NFE2L3; SSX1; POU4F3; CREB3L2; TCF7L2; SETD3; KLF6; ZNF532; ZNF165; TAF5; BAZ1B; ELF4; CBL; ZBTB20; MNDA; IFI16; LHX6; HDAC5; CIR1; ING4; THRA; CAMTA2; ZIM2; FHL5; GFI1; SHOX; NR0B1; SP110; LHX3; AEBP1; TFCP2; EN1; RFX7; IRF2; HDAC7; CEBPE; ZNF512B; INSR; ADNP; NR5A1; SKI; BRF2; ZNF423; ARID4A; OSR2; BNC1; NSD1; SAFB; RSF1; NFE2; RNF141; SP2; ZNF195; ZEB2; HIPK2; PAWR; JUNB; RXRG; PRKDC; HSF1; THRAP3; ZNF587; HAND1; ANKRD1; FOXL2; PRDM10; CREBZF; CARF; NRF1; TERF1; MED23; RFX2; ASCL1; SOX12; ZNF536; BCOR; DDX5; KDM5D; MDM4; PHOX2B; SNAI1; ZNF239; BTG1; NFE2L1; EGR4; E2F3; NR1D2; HOXA1; SMARCA1; ETS2; RRN3; WWP1; TMF1; DNMT3B; THAP10; ZNF611; EMX2; BAZ1A; KMT5A; VDR; MYT1L; HIVEP2; GATA4; CALR; HEY2; KLF5; IRF8; JUP; TAF4; HMG20A; ZNF721; STAT1; SND1; GABPB1; MEOX2; BCLAF1; NANOG; ID3; MED13; ZNF189; KAT2B; E2F2; BCL11B; EWSR1; IRF9; NEUROD1; ZMYND8; ARRB1; CEBPB; FOXJ3; TOPORS; MYBL1; RAD21; ZNF516; ZNF160; MSX1; ZFHX3; ETS1; TRPS1; ZNF551; FOXF2; BIRC2; HOXC4; E2F5; HOXD1; MNAT1; KLF10
Down-regulation	446	HMG20B; PCBD1; PARP1; CRK; PTTG1; NR2F6; PSIP1; ABL1; NRIP1; HOXA10; TLE1; TAF10; WIZ; DEK; TCF25; ZNF589; HOXB6; BRD7; ZFP36L1; EDF1; RFXANK; AES; MBD3; TRIP6; NELFB; ZNF146; HDAC3; ARID5A; NEDD8; TEAD3; ITGB3BP; ERCC3; MEOX1; GTF2F1; GLI3; PCGF1; ZBTB18; ZNF593; HOXB2; SREBF2; IRF3; SMARCD3; CREB3; ATF1; ZNF580; GTF3A; HOXB5; CEBPG; TADA3; SCAND1; PHF1; CRY1; DEAF1; ATF5; ZZZ3; ZNF35; CXXC1; THAP11; ZNF24; TAF11; ATF6; JUND; SMARCA4; CAPN15; SMAD1; UBP1; TGFB1I1; HDGF; BRD4; PPRC1; TGIF2; CCNE1; TAF6; TRIM28; PREB; HOXD9; PFDN5; BNC2; ZBTB48; TBL1X; ZNF32; ZNF692; TULP3; ZNF133; RBFOX2; MMS19; PRRX2; MED6; FHL2; WWC1; RAN; LITAF; HOXB3; TOX4; MYNN; LOXL2; PSMC3IP; ATF3; USP21; SALL2; CENPF; CDK2; EHMT2; CTBP1; LDB1; CHD3; RHOA; CIZ1; THAP4; MLX; EZH2; RXRB; KDM2A; HOXB7; BTAF1; REXO4; CHD1; VEZF1; TRAK1; CNBP; NUP62; MED21; GTF2IRD1; RNF10; RBM14; SIN3B; ENO1; MED16; PEX2; PCGF2; SSRP1; SUPT5H; ZNF219; CENPB; ZBTB38; LZTR1; ZNF768; SMARCD1; ZBTB7A; TLE2; MTDH; CARHSP1; SIX2; LHX1; ATF4; ZIC1; ZBTB17; THAP1; IRF7; COPS5; TRIM27; KMT2B; SAP30; SUPT4H1; FOXO4; SMARCD2; CBFB; PAX6; APEX1; SRF; NFYB; SIX1; ZNF148; ETV2; SP3; URI1; GON4L; TEAD4; HIF1A; SHOX2; ENY2; PLAGL1; ZFX; BRCA1; TTF1; SOX13; TFAM; ZSCAN12; RNF138; PMF1; EED; GTF2A2; ZSCAN5A; SIRT7; MAFF; ZNF131; SMARCB1; SAFB2; ZBED1; THAP7; SUPT6H; TRIM16; MED7; C1QBP; ARL2BP; ZNF771; CIC; FOSB; HDAC6; REST; CARM1; SPDEF; YWHAB; MYRF; ZNF444; E2F6; MED24; CNOT3; ZNF276; ZNF274; CHD8; MED4; HOXD10; HLTF; CBX4; HMGA1; ATN1; TAF9; TCF7L1; APBB1; CREG1; KAT2A; FLNA; ZBTB11; BRD3; SRCAP; MKL2; ARHGAP35; PMS1; MZF1; NR2F2; TCEA2; HINFP; RBM39; RBPMS; ELK1; ZNF202; HTATIP2; SREBF1; CTBP2; ZNF263; AATF; PBRM1; GLI2; MAML1; ZNF248; YBX3; STAT5B; ZFP37; SMAD4; HOXA7; CCNH; MNT; PRPF6; FOXO1; C1D; ZNF44; CBX3; TAF1C; PBX1; CRTC1; MXD3; SMAD6; YY1; CCNC; ZEB1; BATF3; AIP; ABT1; NHLH2; CERS6; NFKBIB; SIM2; MDFI; TRRAP; SLC2A4RG; BMI1; RFC1; ZNF646; NR2F1; ARID5B; ZBTB1; VAX2; ZNF358; NKX3-2; TDRD3; SALL1; NFKBIA; SOX2; ELK3; BCL10; SSBP2; XRCC6; SOX4; TRIM29; KDM5B; FOXD1; ZBTB32; BANP; PATZ1; ZNF85; EP400; CDX1; NCOA3; RFX5; MECOM; DACH1; MAF; BASP1; SF1; CBX6; SIAH2; ZFP64; HOXB9; ZNF281; ZNF410; HNRNPD; CITED1; PHF20; NPM1; ZNF384; ZKSCAN1; RNF4; ZNF91; ATF2; HMGB2; ZMIZ2; USF2; BTF3; SMAD7; EYA2; NCOR2; FUBP1; TLE4; HEY1; ARNTL2; FOXF1; PA2G4; ZNF672; CDYL; TRIM32; NFIL3; NFIB; GATA3; SNAPC4; ERBB4; KAT6A; ALX1; CHD9; MXI1; SPEN; CTCF; MEIS2; ING3; CITED2; CD3D; CREM; ZNF324; CNOT2; ING2; MKL1; ID2; GBX2; BCL3; TEAD1; CDK8; ZSCAN31; SUMO1; KLF7; BAZ2B; RB1; ZNF529; SUPT3H; PIAS3; BACH2; ZNF302; SP140; NR4A2; MTA1; CLOCK; HMGB1; VPS72; CREBL2; TOB1; ELF1; NFIC; CTR9; GCFC2; STAT3; NCOA6; KAT5; DLX2; NFE2L2; ILF2; ZNF329; WWTR1; TDP2; ZNF33B; EGR1; ETV1; PITX1; HES1; CHD7; HOXD3; FOS; SUB1; FOSL1; TRIM22; KAT6B; TFDP1; ZMYND11; COPS2; CNOT6; DNAJC1; IKBKAP; HOXA11; TOX; BHLHE40; CRYM; ZNF12; NR1H3; HIPK3; CBX5; ST18; SOX9; MAZ; SMAD3; PBX3; TGIF1; HOXA5; WT1; DMTF1; CEBPA; NPAS2; YAP1; FOSL2; JARID2; CREB1; MYCN; NCOA4; ERBB2; SOX11; SATB2; ZNF266; MTF2; TFAP2A