Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID55054	Pevonedistat	GSE92742	HA1E	Human	24h	11.1uM	EID0266

Response Information :

Types	Number	Response transcription factors
Up-regulation	45	VGLL4; RORA; NFAT5; TEAD3; CREB5; SIM1; SHOX2; E2F6; CCNT1; SP3; CERS6; OSR2; IRF8; MAFF; RBPJ; HHEX; GATAD2A; HIPK1; TBL1X; ZNF117; ARID4B; RYBP; HEY1; BRD4; ZNF83; ARID5B; ATF3; EMX2; NFATC4; HDAC9; MSX1; ZNF91; NFIB; FOXG1; CITED2; TSC22D2; DDIT3; PAX6; ZFPM2; IFI16; INSM1; NFE2L2; MYB; CDK2; ZBTB18
Down-regulation	39	TP53; CCNA2; NFKBIA; ITGB3BP; HMGB3; BHLHE40; SREBF1; RELB; FOXM1; CENPF; XBP1; E2F5; MAGED1; ZMIZ1; SCAND1; SMAD6; FLNA; PRKDC; ERBB2; SFPQ; PTTG1; SMARCC1; ATF6; NKX2-2; ZNF423; SIM2; PURA; MKL2; SMAD2; POU2AF1; PBX1; CREB3L1; ID1; PBX3; ID3; MYBL1; BASP1; EHF; HES1