Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID55053	Ixazomib	GSE92742	HA1E	Human	24h	10uM	EID0266

Response Information :

Types	Number	Response transcription factors
Up-regulation	184	NR1H2; NCOA3; ZNF394; ZNF408; PRDM1; INSR; CNOT2; ZNF195; ARID3B; DNAJC2; ZNF473; CEBPG; RLF; TEAD3; SNIP1; TRIM24; ZNF136; ZNF787; ZBTB43; MED25; ERCC3; PPARD; POLR3F; SHOX2; ZNF574; KAT6A; PCGF1; ZNF222; RBM39; ZNF107; PRDM4; HOXD1; RSF1; AGO2; ESRRA; ESRRG; CERS6; CEBPA; SIRT7; PIAS1; HSF1; ZNF8; ARID4B; MDM2; SIRT2; HIPK1; TTF1; ZNF35; ZNF557; ADNP2; UBE3A; ASH1L; ZNF562; ZNF432; FOXF2; HMX1; DDIT3; IRF8; MEF2D; ZNF324; CNOT6; ZNF264; MAFG; MED17; RNF10; SP2; LHX3; RNF4; PHF1; POU2AF1; GMEB2; ZBTB7A; RYBP; BAZ2A; PHIP; WWC1; NPAS2; ZNF180; JAK2; ZNF304; UBE2B; CBX4; CARM1; BRD4; TRIP6; ZNF45; ZNF224; MED23; PIAS4; ZNF266; HBP1; SPDEF; ATF4; IRF9; TMF1; ZNF268; SUPT5H; TSC22D3; ZNF426; L3MBTL1; BRD2; ZNF124; HOXD11; CUX1; ZNF83; PPARG; YEATS4; ZNF350; NAB2; ZNF544; SUB1; HSF2; PAX5; MNDA; FOXJ1; ZNF468; FOXK2; ZNF532; KLF13; SATB2; HOXA11; CITED1; NR2C1; ZNF211; ZBTB16; SKIL; SNAI2; TRIB3; ELF3; TAF11; ZNF117; HDAC5; ZNF611; NEUROD1; TFAP2C; TRPS1; MLXIP; HEY1; NFE2L2; GATAD2A; NR0B1; TCF21; BCL3; ZNF134; SOX13; NR4A2; CEBPB; ZNF551; RUNX3; ZBED2; ISL1; CBFA2T3; ZNF331; MEIS2; SPIB; MEIS1; ATF3; TAL1; RFX5; ZNF274; ZNF165; PLAG1; MECOM; IFI16; KDM5D; ZNF91; BTG1; SMAD7; ETV5; MAFB; ZNF721; LITAF; ZNF652; ARNT2; HDAC9; KLF10; JUND; PIR; EMX2; OSR2; PITX1; ZNF586; HES1; NR2F6
Down-regulation	145	TP53; LOXL2; RUVBL1; ASH2L; ATF1; CBX3; CARHSP1; MYC; SAP30; CCNA2; HMGB2; NUP62; HNRNPD; DEK; PATZ1; PURA; BHLHE40; VGLL4; PHF20; CREBL2; SCAND1; NEDD8; KAT8; DLX2; GCFC2; UBE2I; ITGB3BP; ING2; EGR3; PAX8; WWTR1; APEX1; ZZZ3; MAGED1; RBL1; MKL2; CENPF; ZMIZ2; RNF141; NCOA4; HOXB9; SMARCA5; VEZF1; PRMT2; MXD3; TSC22D2; CENPB; TRIM27; RBPMS; ENO1; FLNA; ERBB2; USF2; SMAD3; TFAM; PMS1; NFKB1; FOSL1; SMARCC2; HLTF; POLR2A; TAF6; SUV39H1; HOXC6; HLF; PARP1; HMGB3; GTF3A; MED7; TCFL5; MEOX1; SMAD2; LZTS1; HMGN3; FOXM1; PA2G4; RBBP7; ZBED1; BRD3; KLF2; SMARCA2; CDK8; SMARCC1; NR1H3; SMARCA1; ZNF32; DPF2; BRCA1; ZNF552; HSBP1; PITX2; POU4F1; ZEB2; PTTG1; ID4; RBBP4; KLF6; MYCBP; PRPF6; SMAD1; RUNX1; BNC2; NFE2L3; PAWR; EGR4; DDX17; NFKBIA; FOXN3; SOX9; SOX4; HOXB7; YWHAB; LPIN2; HMGA2; ZFP36L2; ZFP36L1; NFIB; TCF4; MTA1; LIN28A; PLAGL1; ID2; PAX6; SPEN; MYBL1; SOX11; TGIF1; ZBTB20; ERG; MEOX2; MED1; TOX3; ZBTB18; NR2F2; PBX3; DMTF1; HOXB6; KAT6B; LMCD1; PTRF; KDM5B; TSC22D1; TXNIP; ARID5B; BIRC2