Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54936	Tipifarnib-p2	GSE92742	HA1E	Human	24h	10uM	EID0268

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	RHOA; SPDEF; ZNF589; MBD4; ZNF426; HES1; ZNF571; ZNF133; ZNF266; BLZF1; KAT2A; NR0B1; ZNF529; NR0B2; ZNF506; TSC22D3; PTTG1; ZBED2; ZNF282; TADA3; ING4; TBX19; FOXA1; ZNF155; RFX7; ZBTB32; RARG; SMARCD3; PPARD; TCEA2; ZNF227; PBXIP1; SETD2; EHF; EZH2; ZNF675; ZNF444; ZNF292; THRA; CUX1; POLR3F; HOXB13; PRMT2; ZNF345; MAK; L3MBTL1; CRYM; TRIP11; TRIM25; RRN3; ZNF141; MED24; SIX1; CEBPA; SOX12; ZNF205; ZNF623; ZNF350; ZNF468; PIAS3; TAF11; MED6; EMX2; ZNF710; TLE2; MLXIP; ARNTL2; ASXL1; SETDB1; ZNF107; ZNF136; ZNF692; MAX; STAT3; BCL11A; MDM2; KDM5D; MED7; AR; TBX2; DLX5; ZNF224; YEATS4; CTBP1; HDAC7; PLAGL1; ZNF184; SERTAD2; RFX5; RSF1; STAT2; GTF2I; BACH1; PAX5; NKX2-1; IKBKAP; ELF5; NONO; NFE2L3; MNAT1; CENPB; ZNF432; ILF2; KAT6A; ZNF337; TTF2; NELFB; ZSCAN9; AEBP1; FOXA2; ZMIZ1; PLAGL2; SUPT4H1; TOX3; ZKSCAN7; HMGA2; ATF7IP; NPAS2; ARNT; SSX1; TAF9B; ZNF83; PAX6; ZKSCAN1; RBPJ; GRHL2; E2F5; TCF21; RUNX3; NR2F1; PEG3; PITX1; MECOM; HOXB2; MED21; EGR3; MSX1; YBX3; CD3D; HLX; MTA1; SOX9; BACH2; HMG20B
Down-regulation	215	ATF5; SMAD3; BRD7; LOXL2; LIN28A; HOXD3; DLX2; ZMYM2; CNBP; NR2F6; PPRC1; CHD1; PREB; INSR; EYA1; ZBED1; USP22; TBPL1; TERF1; SCAND1; SMAD1; HOXD9; GLI2; TBL1XR1; ZNF423; SMARCA5; HOXC6; PMS1; CBFB; NFRKB; TP53; PATZ1; TFDP1; SF1; ORC2; ZNF593; SPI1; SP3; SFPQ; NANOG; HOXD1; SMARCA4; BRD3; SPEN; TBL1X; SAP130; BRD2; RNF6; TSC22D2; SNAI1; BAZ2B; ZNF721; SMARCE1; RCOR3; ZNF93; TLE4; MTF2; BRD4; ZNF160; KMT2A; HOXC5; RNF138; CTBP2; ID2; HOXC10; MED1; HOXA7; ATF3; NLK; GTF3A; MTDH; MED17; HOXC4; POU5F1B; SAFB2; EP300; HDAC1; UBE3A; TAF10; MNT; RREB1; AFF1; ARID1A; PRRX2; ZNF544; PRDM14; ARID5B; LMCD1; SMAD2; CBX3; TRIM27; NFE2L1; ING3; TFDP2; BIRC2; NR3C1; UBE2B; ZEB1; ZNF189; BCLAF1; HSF1; ADNP; ID3; BAZ2A; HOXD11; KLF9; COPS2; CTCF; ZSCAN18; SOX15; MYCL; CNOT1; TFCP2L1; TGIF2; TWIST1; PEX2; MXI1; ZNF202; CHD9; NR1I2; KAT6B; COPS5; BRD8; ATF4; ELF1; REST; NPAT; CAMTA2; RBBP8; BCL3; NAB1; BBX; MAFF; RNF4; TCF7L1; CCNC; SMAD4; FOSB; RAN; NR2F2; GATAD2A; ZNF124; SMARCA2; HMGA1; ING1; ENY2; NFATC4; TCF7; TOB1; VDR; LHX6; JUND; KLF4; PQBP1; PSMC3IP; ERG; ERBB4; CENPF; CBX4; ING2; TCF7L2; ZBTB18; ESR1; CEBPZ; MEOX2; TBX3; CREB3L1; MEOX1; PHF1; TFAP2C; HSBP1; HMGB1; TRIM29; KLF7; NR1H3; MAFB; PHF20; CITED2; FOXC1; AGO2; TAL1; CSDE1; FOXN3; CTR9; EDF1; SNAI2; KLF2; APEX1; ZFHX4; POLR2A; ZNF430; ZNF91; RBPMS; FOXO1; STAT1; NCOA2; SATB1; FOXD1; MAF; KLF10; TERF2; IRF7; ZFP36L2; JARID2; ZHX2; ZBTB20; VEZF1; CEBPD; TGIF1; ZNF131; CREB1; ADRB2; PBX1; DACH1; IFI16