Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54905	Pevonedistat	GSE92742	HA1E	Human	24h	11.1uM	EID0268

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	NFE2L2; TSC22D3; TBL1X; ZNF44; CREB5; E2F6; TEAD3; JAK2; CEBPG; BACH1; NFAT5; HINFP; RYBP; RFC1; ATF3; ZNF136; BCL6; FOXO4; TTF1; RORA; ZNF562; SIM1; SIAH2; PAXBP1; ZNF107; ELF2; SUPT4H1; TBPL1; ZNF117; CBFB; ZNF43; KLF7; NLK; ESRRG; IRF8; ZNF3; REL; SMAD3; BCL10; NFATC4; ZNF654; PCGF3; ZNF177; NRBF2; MEF2A; RBBP8; BANP; GATAD2A; HBP1; RBPMS; ZNF443; ELF1; ZNF232; ZNF468; SHOX2; MTF2; HDAC5; NAB1; RNF6; ZNF22; CBX6; MSX1; MAFG; IRF6; ARID5B; ZNF267; ZNF331; ZBTB43; ERBB4; SP100; ARNTL2; MNDA; MYB; PLAGL2; AGO2; DDIT3; EYA2; TCF4; OSR2; ZNF131; ZBTB18; HOXC6; HDAC9; DNAJC2; KLF9; HLF; ZFP36L2; ZNF264; MXI1; PEG3; CITED2; ZNF83; TSC22D2; HLX; NFE2; MAF; ZNF281; HOXB2; HEY1; LEF1; CRK
Down-regulation	80	NFKBIA; ERBB2; TP53; ZNF589; PDLIM1; SMAD2; HNRNPD; SMARCA4; SMAD6; HMGB3; EP400; ADNP; CDX1; IRF4; PAX8; PTTG1; CCNA2; ID1; TRIM22; CBX5; MAGED1; SMARCC2; RELB; CENPF; SSX1; CNOT3; ZMIZ1; RERE; NPAS2; CRYM; MED1; NCOR2; FOXM1; SREBF1; SFPQ; BHLHE40; ARID1A; MKL2; PITX2; TGFB1; HOXB13; TRIM32; HMGN3; EHMT2; XBP1; IRF2; ID2; ITGB3BP; PRKDC; ID3; TRIM16; AES; SIM2; NFE2L3; FOXA1; PURA; KDM5D; FOSB; TGFB1I1; ZBED2; ELF3; CREB3L1; JUNB; ZNF423; PBX3; BASP1; POU2AF1; TCF21; SOX13; HES1; FLNA; PBX1; NR2F1; BHLHE41; DACH1; MEIS1; ID4; TFAP2A; TCFL5; E2F2