Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54825	Tivozanib	GSE92742	HA1E	Human	24h	10uM	EID0268

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	SOX2; FOXO4; TCF7L1; EYA1; INSR; CRYM; CBX5; SAP130; TSC22D3; BRD7; TEAD3; CUX1; MYCL; TOX3; ZSCAN18; IRF6; SP2; NKX2-1; PBX2; SREBF2; SOX4; ZNF44; FOXO3; HMGN3; PNRC1; ARNT2; RBBP8; PIR; SIX3; MED16; TRIM22; ELF5; TRIM33; ZNF536; ZNF268; KMT2A; SOX3; NR2F1; AES; SOX12; ARID1A; ERBB4; ARID5B; ARID3B; SALL2; TP63; LIN28A; RBPMS; STAT6; ZNF331; ELF1; PBXIP1; ST18; TGFB1I1; MEIS2; FOXA2; JUP; SLC2A4RG; AEBP1; CHD4; SIM2; ZNF532; ZNF423; CITED1; BRD4; PLAGL1; HMGB2; TOX; HBP1; OSR2; MNT; TWIST1; KDM5D; MYRF; ISL1; CEBPD; STAT4; TGIF1; IRF9; HLF; FOXG1; TRIB3; ZNF512B; LITAF; SMARCA2; SALL1; LMCD1; EMX2; KAT6B; RFX5; TLE4; NCOA2; PBX1; HOXA10; INSM1; FLNA; ID4
Down-regulation	77	FOSL1; LOXL2; RHOA; HHEX; TFAM; MYCBP; RUNX1; ELK3; MAX; ZNF576; HCFC2; WDR77; SMARCE1; SSX1; BATF3; PITX2; ZNF593; C1QBP; CRY1; IRF8; DLX2; ID3; MYF6; MLX; SREBF1; REST; NCOA4; FOXC1; RUVBL2; ENO1; APEX1; CDK8; UBP1; NAB1; HOXB6; YAP1; HOXC10; TRIP6; CDYL; GATA4; PLAG1; NOC2L; SMAD5; BTAF1; PURA; BHLHE41; SKI; MED1; BATF; SATB2; GTF3A; ZFPM2; BIRC2; BASP1; BMI1; ETS2; GTF2I; HES1; MEIS1; RXRA; SMAD1; KLF10; HOXB5; KLF6; HLX; HOXB7; ZBTB18; ZIC1; JUNB; FOSB; HTATIP2; HOXB2; TBX3; IFI16; LEF1; TCFL5; E2F2