Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54666	Mk-1775	GSE92742	HA1E	Human	24h	10uM	EID0267

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	TCEA2; EED; ZNF304; ZNF264; MED17; ZNF180; TDP2; ZSCAN9; SSBP2; TRIB3; RRN3; NFE2L2; ZNF573; ZNF551; RAD21; SUPT4H1; ZNF43; ZNF211; SNAI2; NEUROD1; ERCC3; BTG1; ZBTB7A; ZNF688; ST18; INSM1; MEIS2; NHLH2; ZNF574; ZNF136; SMARCC2; SALL2; HOXD1; ZNF195; PIAS4; IRF6; ZNF354A; IRF8; ATF3; E4F1; ZNF227; BRD4; CBFA2T3; CEBPG; ZNF562; ZNF415; ZNF423; PCGF1; CDIP1; ZNF83; HLX; ZNF12; ZNF586; THAP4; SIRT7; CBX7; EN1; IRF9; HDAC9; SOX11; FOS; FOXO4; INSR; ARNT2; TRPS1; VPS72; SP110; E2F8; ZNF3; ZNF331; ID1; PHIP; DAXX; ZFPM2; PNRC1; DDIT3; HIPK1; CD3D; JUP; HOXB5; NAB2; MYCL; EHF; OSR2; SOHLH2; TOB1; ZNF44; CBX4; KAT2B; MYBL1; KLF5; ZBED2; MDM2; WT1; CUX2; PAX6; E2F5; TAF11; ZIC1; CDC5L; THAP10; CREBL2; AES; PBX3; HIC2; AEBP1; SSX1; IRF7; ZNF91; PEG3; ZNF329; ACTL6A; MNDA; TRIM22; THAP11; CEBPB; SOX9; PPARD; DLX5; MAFB; TWIST1; TXNIP; ZFP36L2; NR2F1; CREB1
Down-regulation	110	HOXA5; PAX8; LOXL2; NRIP1; RBBP4; MYC; TBP; ECD; HOXA10; FHL2; RHOA; FOXO3; HOXA1; CCNA2; NCOA4; ENO1; ATF1; CRK; SFPQ; NFIB; CBFB; AFF1; HOXA7; BTAF1; NFIL3; SMARCC1; PURA; ATF6; BAZ1A; RBPMS; ELF1; HNRNPD; ASH2L; LIMD1; GATA4; YAF2; RNF14; TLE1; ZMIZ1; NCOA6; BHLHE40; TBL1XR1; ZNF131; KLF6; RARB; APEX1; SETD3; TCERG1; GABPB1; CALR; NEDD8; PBRM1; LPIN2; DNAJC1; PMS1; STAT3; SALL1; BMI1; PIAS2; SOX4; TBX3; KLF2; DNMT3B; ID2; RUNX1; NPM1; BATF3; SMAD2; TRRAP; WWC1; ASXL1; HOXC6; SMAD6; PRKDC; TFCP2L1; NPAT; BRD3; ELK3; YWHAB; KDM5D; SMARCA2; CARHSP1; KDM2A; TRIM16; HOXC10; HOXD10; TFDP1; FOXC1; HOXC4; WWTR1; IRX5; XBP1; ZMYM2; TCF4; IRF4; POLR2A; ZBTB38; PPARGC1A; NCOR2; ZEB2; SPEN; FLNA; CBX3; NR1D2; MBD2; LMCD1; DACH1; MTA1; SMAD7; ID4