Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54613	Fostamatinib	GSE92742	HA1E	Human	24h	10uM	EID0265

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	TCEA2; ZNF345; SETDB1; PIAS4; ZNF219; ZNF74; ZNF682; NR1H2; HSF1; TCF7L1; E4F1; PNRC1; ZFP36L2; ZNF574; ZNF141; FUBP1; SMARCC2; PRDM2; RAD21; FOXM1; ARHGAP35; NHLH2; MED14; SIRT2; CUX2; VPS72; WHSC1; ARNT; TGFB1; CDIP1; ZNF623; KAT6A; CHD8; LZTR1; PBXIP1; TRIB3; SALL2; ZBTB3; CALCOCO1; NCOA2; DNMT1; ZNF423; ING4; ZNF500; ZNF180; L3MBTL1; ARNT2; SCMH1; HOXA10; ZNF22; TCF3; CHD4; PBX1; PEX14; MAML1; ZNF444; ZNF224; KLF11; SMARCB1; EHMT2; HMGB3; CTCF; CNOT3; SOX11; TCEB2; SCAI; POLR3C; CARF; HESX1; SPI1; ZNF83; RING1; TULP3; MBD4; NAB2; LDB1; MED12; INSR; ZSCAN9; ZNF711; ZNF254; ZNF135; AEBP1; MYBL2; BACH2; SOX12; ST18; BCOR; ZNF232; CBFA2T3; ZNF117; HOXB5; E2F2; PBX3; HINFP; SUPT5H; ZNF43; CBX5; ID1; JUP; ZIC3; ZNF544; TCF7L2; CREM; POU2F1; PFDN5; BRD4; ZHX2; FOXO4; AR; TDRD3; HOXB2; ZNF415; ZNF302; ZNF44; NR2C1; CBX7; ZNF573; ARID1A; SPDEF; BAZ2A; ZNF665; AES; HDAC5; ZNF227; MED24; TTF2; RBPJ; MNT; TCF25; ZNF611; NANOG; TAF6; ZNF264; PIAS3; IRF6; MEF2C; CARHSP1; POU5F1B; ZBTB16; HHEX; IRF9; ZNF268; DACH1; PSIP1; WT1; FOXK2; MEIS2; OSR2; JUND; FOXN3; ZNF195; LIN28A; ZFP36L1
Down-regulation	130	MYC; ECD; NRIP1; USP16; FOSL1; NCOA4; MAFF; RUVBL1; COPS2; BATF3; CDK7; RHOA; YAF2; SFPQ; BAZ1A; NFIL3; CCDC59; NPM1; ALX1; BCLAF1; NFKBIB; SOX10; ORC2; PHOX2A; C1QBP; HSBP1; ASH2L; CCNA2; TEAD1; BCL10; GABPA; ING3; ZFP64; GABPB1; MAX; MED1; KMT5A; ZEB2; MLX; PURA; UIMC1; RAN; BRPF1; DR1; CHD1; BTAF1; CCNC; RNF6; ZMYND11; YWHAB; KLF12; SIRT7; IKZF5; SMARCA5; PEX2; ELK1; RNF14; SETD3; IRF4; UBP1; ADRB2; ZNF672; EGR3; EDF1; MED27; ELK3; CTNNB1; RBM14; FOXD1; ETS1; MED6; RBM39; NPAT; TRIP6; TRIM25; ETV6; SATB2; ETV4; NCOA6; HOXC6; IRX5; CREB3L1; ZBTB43; CBFB; JUN; SMAD2; SERTAD2; THRAP3; BATF; ENO1; NAB1; COPS5; SOX15; ZZZ3; TRIP4; TSC22D4; PRRX2; ING2; CHD7; BMI1; KLF2; KDM2A; PSPC1; FOXL2; ZBTB11; PIAS2; MAFG; HIPK3; CTR9; BBX; BRD3; STAT3; MTF2; RUVBL2; MYCBP; FOXC1; HMGA2; ZMYM2; CHD9; CNOT1; CEBPZ; EGR2; ARNTL2; AFF1; POLR2A; TRIM32; PITX2; HOXC10; SP140L; ZNF443