Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54597	Pevonedistat	GSE92742	HA1E	Human	24h	11.1uM	EID0265

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	VGLL4; TEAD3; CREB5; SHOX2; SP3; NR1H2; RORA; SIM1; TFE3; E2F6; ESRRG; ARID3B; OSR2; MAFF; CCNT1; ZNF143; NFIL3; CERS6; ATF3; NFAT5; EZH1; DNAJC2; ZNF263; BRPF1; HIPK1; NLK; LHX6; ARID5A; HHEX; MAK; UBE3A; BRD4; NFATC4; ARID5B; RFC1; ZNF394; ZNF324; TAF9; SERTAD2; TBL1X; BAZ1B; ZBTB7A; GATAD2A; BTAF1; RYBP; NCOA3; E2F3; HCFC2; RNF138; PIAS1; RBPMS; MAFG; ZNF136; MEF2D; ZNF267; ZBTB43; FOXO4; HDAC7; SUPT4H1; RLF; RBPJ; RNF6; HEY1; HINFP; SP100; WWP1; HDAC5; ZNF117; ZNF107; IRF8; HBP1; PAXBP1; FOXG1; MITF; MSX1; NR5A2; PCGF1; BRD2; TAF1D; FOXA1; AR; BBX; FOXJ1; SAFB2; TCF15; HDGF; ZBTB11; ZNF304; TSC22D2; ZNF83; BACH1; TRPS1; ZNF410; MLX; ZNF148; CAMTA1; IFI16; ZNF91; HDAC9; ESR1; DDIT3; IRF1; YAP1; SIAH2; PGR; TGIF1; EN1; CHD1
Down-regulation	82	TP53; CCNA2; LOXL2; NFKBIA; HMGB3; TCEA2; MAGED1; CENPF; FOXM1; RUVBL1; BHLHE40; RELB; E2F5; PSMD9; ITGB3BP; XBP1; ZMIZ1; ASH2L; ERCC2; SREBF1; MED7; SMAD6; PTTG1; TCF25; NPM1; NKX2-2; KLF12; GLI2; PURA; PITX2; ERBB2; WDHD1; TERF2; HNRNPD; CREG1; SIM2; ZNF33B; NCOR2; ZNF423; CBX5; HOXB9; SMAD2; FLNA; PRKDC; SCAND1; TAF9B; SFPQ; MYT1; HIVEP1; ATF6; SMARCB1; RUVBL2; PHOX2B; BLM; ID3; BCLAF1; SMARCD3; MLLT10; NFE2L3; BRD8; CREB3L1; MKL2; ZNF32; NUP62; SMARCC1; ZKSCAN1; POLR2A; BASP1; ZNF552; PBX1; PKNOX2; APEX1; PBX3; YEATS4; NONO; TRIM16; HMGB2; TCEA1; PAX8; ZMIZ2; PRMT2; PRRX2