Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54542	Triptolide	GSE92742	HA1E	Human	24h	0.08uM	EID0265

Response Information :

Types	Number	Response transcription factors
Up-regulation	301	TCEA2; WNT4; ZNF136; SPDEF; ZNF10; ZXDC; L3MBTL1; ZNF264; ZNF551; TWIST1; ZNF304; ZNF562; ZNF174; ZNF345; CARF; CDIP1; NR1H2; ZNF268; ZNF623; ZNF695; NR4A2; INSR; PRDM14; MEF2C; TGFB1; NCOA3; IRF1; CREG1; ZNF682; ZFPM2; BAZ2A; ZNF573; ZNF211; CBX4; ZNF44; NHLH2; TOPORS; ZNF117; ZNF408; HBP1; ZNF3; ZNF816; SOHLH2; ZBTB3; ARID3B; ZNF180; MED14; ZNF184; ZNF394; ZNF557; TP53; ATOH1; ZNF83; ZNF75D; ZIC3; ZNF131; ZKSCAN4; NFE2L3; MZF1; MECP2; IRF6; THAP10; DOT1L; SOX18; SRY; ZNF224; EP300; ZBTB39; SNAI2; ZNF544; SOX11; ZNF556; MEIS2; ID3; ZNF419; ZNF426; ZNF468; POU4F2; FOXA1; SALL2; CUX2; TCF21; ZKSCAN1; HOXD1; HOXB1; ZNF12; MED17; BACH2; ZNF701; PAX1; AR; ZNF688; SOX3; OSR2; ZNF14; ZNF771; ZNF529; MYCL; ZNF154; ZNF711; CCNT1; TAF12; TERF1; ZNF587; ZNF350; ESRRA; ZNF492; CHD4; NR5A2; PRDM2; VGLL4; GFI1; ZNF200; NR5A1; ZNF257; NOC2L; ZNF500; KLF13; AEBP1; BCL11B; ZNF8; ST18; ZBED4; ZNF440; ZBTB43; SP140L; CITED2; LZTR1; ZNF235; ZNF536; ZNF141; ZNF665; ZNF611; ZNF432; ZNF232; ZNF195; KLF15; CERS6; LHX3; WT1; ZNF331; ZNF7; RING1; PEG3; TAF4B; PIAS4; ZBTB48; RRN3; ZNF667; ZKSCAN5; CD3D; ZNF423; ZNF813; ZSCAN32; ZNF778; MED12; ZNF222; CNOT3; HOXB5; THRA; RSF1; SNIP1; IRF9; FOXF1; TCEB2; BNC2; ZNF24; HOXD3; BCOR; RERE; ZNF107; SOX13; ZNF225; HIPK2; PBXIP1; HESX1; ABT1; SPI1; TOX; NANOG; ZNF254; ZNF112; TSC22D3; BRD2; MYCBP; SHOX2; SUPT4H1; INSM1; ISL1; HMBOX1; MYRF; NR1I2; PPARD; RARG; ZNF606; PRMT2; VENTX; ID1; TTF2; JUP; ZBTB20; IKZF1; TAF1; CALCOCO1; SKI; TAF11; ZNF43; ZNF223; TFDP1; ZNF334; PBX3; CERS4; FOXO1; HIRA; ZNF787; ARNT; ARID1A; PCGF3; ZBED2; HDAC1; PIAS1; HDAC5; ZNF45; ARNT2; ZFP69B; ZNF177; ZNF512B; EGR1; HHEX; TCF7L2; DACH1; TGS1; NFATC3; TRIB3; HDAC4; TDP2; ZNF571; SOX5; TRIM22; AHR; ZNF329; HAND1; LIN28A; NR4A1; ETS1; DBP; HLX; PAWR; CDK9; PFDN5; ZNF134; SSX1; TGIF2; UBE3A; E2F5; VDR; AES; REL; ZNF467; ZNF165; PARP1; MXI1; LEF1; ZNF580; NR2C1; HIPK1; ZNF124; SKIL; VPS72; RNF6; TOX3; HLF; IRF8; FOXN3; IFI16; HIC2; CALR; SREBF1; ZSCAN31; BRD4; HDAC9; ZMYND8; GATA6; HMGN3; E2F2; ZNF430; KLF7; MEOX2; GLI3; KDM5A; ZBTB16; NEUROD1; CBX7; NKX2-1; FOS; NKX2-2; ESR1; TBX2; BHLHE41; HEY1; SATB1
Down-regulation	364	PAX8; NFIL3; FHL2; TLE1; ECD; CCNA2; ATF1; SNW1; JUN; DDX54; MYC; DEK; NUP62; TCERG1; FOXO3; EED; SP3; CHAF1B; EZH2; TBP; PSMD9; NRIP1; BRD3; HOXA10; CDK7; CENPF; YAF2; HOXA5; BHLHE40; HNRNPD; KAT7; XBP1; HDAC2; RBM14; FOSL1; REPIN1; SUZ12; ASH2L; SMARCD2; SFPQ; CDYL; USP22; ZNF672; BATF3; RAN; BCLAF1; TGIF1; BMI1; BRCA1; TBL1XR1; NPM1; PATZ1; HDGF; CCNC; GTF2IRD1; ORC2; UIMC1; HOXA7; NRF1; ZNF410; SAP30; BAZ1B; DNMT3B; SMARCA5; CNOT1; CARM1; BAZ1A; MSC; TCF20; NPAT; ZNF282; ZNF146; ATF5; HOXC6; AATF; BLM; PUF60; HOXB9; CRY1; TADA2A; PQBP1; ZSCAN16; WWC1; SOX4; SF1; NCOR2; ZNF143; ZBTB40; CBX3; TAF9; RNF111; NCOA4; VEZF1; SETD3; TAF5; NEDD8; EWSR1; TRIP6; TCF12; RREB1; KLF1; ZBTB1; MED27; ZNF292; LIMD1; PRDM4; KAT8; NFKBIA; ZMYM2; RBBP4; SIAH2; MGA; VSX1; HOXA6; ZNF248; PMF1; SSRP1; ELF1; PSPC1; NAB1; RXRB; TRIM32; USP21; LMX1B; ZNF692; USF2; ADRB2; LHX1; WDHD1; HCFC1; AFF1; KAT5; HOXB3; UBP1; SMAD1; APEX1; PCGF2; SFMBT1; MED6; KLF12; TEAD4; TRIM16; LOXL2; BRIP1; ZMIZ1; TLE2; NCOA1; HABP4; RELB; RBBP7; MDFI; SOX10; DEAF1; PLAGL2; ING3; CASZ1; STAT5B; SMARCE1; RARB; HDAC6; MED7; ELK3; PMS1; HOXC10; RFXANK; MITF; GCFC2; KLF6; ZBED1; PURA; POLR2A; ZBTB38; HOXD9; MAFF; NFE2; ZFP64; TRIP4; PTTG1; RUNX1; TSC22D1; ADNP; FOXM1; DDX5; PCGF1; ERBB2; CENPB; MNAT1; FOSL2; MYF6; MED13; NSD1; ITGB3BP; MKL2; EDF1; COPS5; NFYB; PHF2; MED21; MAZ; CHD1; TSC22D2; TFE3; FOXD1; MLX; HMGB2; MXD3; ZNF384; SIX2; STAT6; PITX2; HTATIP2; HSBP1; DNAJC1; SMAD7; FOXC1; IRF5; UBE2L3; ANKRD1; ZMIZ2; HDAC7; TCFL5; JUND; CCDC59; CDX2; TSC22D4; SMARCD3; GFI1B; RBL1; MYBL2; ZHX3; DDX17; CCNE1; ELK1; MED4; TRIM27; RCOR3; TRIP11; NFKB1; SUB1; ARID3A; AGO2; ETV1; BTF3; BANP; PPRC1; ALX1; ELF3; ING2; LPIN2; ARID4A; HIVEP2; SETD2; ZBTB32; ATF7IP; RELA; HLTF; RXRG; TAF4; ENO1; MED1; ETV4; CTBP2; CBFB; GTF2A2; NCOA6; BRD7; SMARCC1; SIM1; TFEB; ASXL1; CITED1; CARHSP1; PRRX2; ZNF337; SMARCB1; SOX9; HOXC4; NFIB; ARNTL; CTCF; ILF2; ATF4; HOXA11; DPF2; DNAJC2; IRX4; JARID2; NR3C1; TULP4; E2F6; MED15; SALL1; ABL1; BARX2; NELFB; KLF10; SIM2; ZNF629; E2F3; LMCD1; CDK8; CRYM; MED20; FOXO4; ZBTB24; RXRA; CNOT2; ARRB1; STAT5A; SAP130; HMGXB4; TRIM25; REST; ZNF267; MLXIP; CBX6; BASP1; HOXB7; C1D; SAFB2; STAT3; NR2F6; SRF; LYL1; ZIC1; HIF1A; EYA2; ZMYND11; ZNF133; IRF7; MAX; SMARCA2; THAP11; ARNTL2; NKX3-1; CREB3L1; BATF; OLIG2; BRD8; ARID4B; CNOT6; SIX1; CLOCK; SUV39H1; MSX1; ZNF32; ZNF217; SMAD2; HMGB1; HMGA1; TFDP2; BACH1; ERG; TFEC; YEATS4; KLF2; PREB; HSF2; TRIM29; ZEB2; RORA; PRRX1; ID2; BCL3