Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID54322	Doxorubicin	GSE92742	HA1E	Human	6h	10uM	EID0264

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	ZNF131; ZNF423; NR1H2; NR2F1; SREBF2; SOX11; SPDEF; MYF6; RING1; HOXB13; TGFB1I1; IKBKAP; ST18; GRHL2; CUX2; ZNF835; SRCAP; SUMO1; AEBP1; CBFA2T3; AES; TTF2; TGFB1; MEIS2; CERS4; ZNF528; SSBP2; TAL1; CSDE1; PRRX1; PSMC3; NFE2L3; EHMT2; WDR77; INSM1; YBX3; SLC2A4RG; HDAC9; ZNF415; ZNF117; NEUROD1; HMGA1; TDP2; CALR; NHLH2; RAD21; EHF; MYT1; JUP; CTNNB1; MED12; ZNF711; ZFPM2; ACTL6A; URI1; BCL11A; NR4A2; KDM5D; TCF4; PBX1; IRF6; MNAT1; ZNF532; TCEA2; MAZ; FOXF1; TXNIP; ZNF43; MEIS1; NKX2-2; MECOM; MTA1; CREB1; ZNF91; HEY1; TFAP2A; ZIC1
Down-regulation	253	NFKBIA; HOXA5; FOSL1; FOXJ3; MYC; NFIL3; NUP62; HOXA10; SUV39H1; FOXO3; CCNA2; ID2; KDM5B; ELF1; TBP; BRPF1; USP22; SMAD7; ZNF410; FHL2; SCAND1; JUN; ADNP; NPAT; ASXL1; RNF111; SERTAD2; ZNF84; SMAD2; BCL10; TOB1; VGLL4; SNW1; ZBTB43; TSC22D2; ZBTB1; PHF20; TAF1D; UIMC1; NCOA6; VEZF1; ZNF267; NRBF2; HOXA1; HES1; PPARGC1A; AATF; KDM2A; PLAGL2; PKNOX1; CDK7; SMAD3; SETD2; BRCA1; EED; BRD8; SAFB2; SOX4; ING1; GON4L; TBL1X; TRAF6; TRIM32; PATZ1; GATA4; DNMT3B; NRIP1; ZNF202; AGO2; SFMBT1; PURA; HOXC6; SUZ12; MAFF; RNF4; DR1; ZBTB11; AIP; TMF1; BANP; AFF1; ZFHX4; ZNF443; NKX2-1; SP140; POLR2A; ZBTB25; KAT6A; ZZZ3; HCFC2; EGR2; ZNF263; ARID4A; BRD3; CHD1; BTAF1; ELF4; HOXA11; NFRKB; TRAK1; ADNP2; ANKRD1; ARID4B; E2F3; DPF2; TOPORS; NR2F6; PQBP1; ZNF148; ZNF45; TAF4; VDR; NCOA4; CREBZF; REST; ZMIZ1; FOXC1; KMT2A; PAX8; MTF2; REL; CBFB; NR3C1; CHD8; KAT7; DDIT3; FOSL2; XBP1; ZNF248; ZNF7; SIAH2; TTF1; ZNF189; YAF2; SALL1; PPRC1; AHR; CRY1; FUBP1; POLR3F; ARID5B; RCOR3; TLE4; JUND; ING3; CEBPZ; CCDC59; RREB1; BCOR; BCL3; MAFB; PIAS2; ATF7IP; MED17; RCOR1; DDX17; MED6; IRF4; ZFP64; ZBTB40; BHLHE40; MNT; SPEN; SIRT7; PAX5; ZNF200; BAZ1A; ERF; BAZ1B; SIN3B; LIMD1; BIRC2; BLM; JARID2; REXO4; RARA; TCFL5; ZNF672; HOXA7; ZNF14; SAP30; TFAP2C; CCNE1; FOXD1; MGA; RBM39; MED7; MAFG; ZFP36L2; WWTR1; PSPC1; RNF138; HOXB7; E2F8; BASP1; ELK3; NKX3-1; DNAJC1; NR2F2; ZNF266; ZEB2; ZNF165; TGIF1; DDX5; STAT4; NR4A1; LITAF; FOXO1; MYRF; GABPB1; RLF; ATF3; TAF9; ZHX2; ZNF721; KLF10; MED1; BRD2; DMTF1; BATF; EDF1; MYBL1; WWC1; ARNTL; ZNF217; EGR3; MKL2; BRD4; YWHAB; TFEC; POU4F1; KLF9; RYBP; CREB5; KLF6; FOS; HOXB6; HHEX; CHD7; ZBTB18; IRX5; TLE1; CTBP2; ZFP36L1; BHLHE41; ABL1; HOXC10; TSC22D1; KLF2; ESR1; SOX9; ID4; NFATC3