Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID53777	Mitoxantrone	GSE92742	HA1E	Human	24h	10uM	EID0261

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	CREG1; HES1; SPDEF; FOXF1; SOX11; RHOA; PRDM1; EGR1; PBX1; FOXA1; PITX1; HIF3A; IRF8; ZNF710; RBFOX2; ZEB1; RSF1; SSBP2; TCF21; PAX6; HMBOX1; BCL11B; NR2F1; MECP2; MEIS2; ZNF589; SSBP3; ZIC3; CD3D; AR; GLI3; CSDE1; OVOL2; ZNF264; KLF7; ZNF528; NFAT5; ZNF835; PPARD; GRHL2; IRF6; MEIS1; SLC2A4RG; CHD9; ZNF816; PRMT2; BCL11A; THRAP3; AES; ATF6; TCEA2; ZNF467; NFIC; ZNF211; CDK2; PAX9; BNC2; ZBTB44; CALR; CHD3; TCF4; HOXB5; LZTR1; AFF2; TCF7; BCL6; SSX1; ZSCAN31; KDM5A; EHMT2; ASH1L; HDAC6; SMARCA1; ZNF117; EPAS1; TWIST1; NR5A2; RING1; SHOX2; MEOX2; TRIM25; PIAS1; SATB1; ZNF652; ZNF415; ZNF219; YBX2; TRIM22; MECOM; TAF6; SALL2; ZNF141; FOXA2; ELK4; SIX6; POU5F1B; MLLT10; ISL1; RNF141; PLAG1; HIVEP1; SP140L; WNT4; SUMO1; SMAD5; ATN1; HAND1; HMG20B; MYCL; HIPK2; TXNIP; SRCAP; ZNF611; SOX2; PLAGL1; HOXB13; VPS72; REL; ALX1; IRF1; PEX14; DBP; SOX13; KDM5D; CUX1; ZNF532; HBP1; RARG; CERS6; FOXN3; NR4A1; ZNF384; SOX17; LZTS1; ZNF711; KAT2B; CREBL2; TFEB; NKX2-2; TEAD3; ZKSCAN1; ATF3; KAT6B; CREB1; HOXB2; ETS2; FOXF2; SIX2; SUB1; HMGA1; CBX7; ARNTL2; IKZF1; MNAT1; ERBB4; BACH1; YBX3; NEUROD1; HOXD3; EHF; ZFPM2; ST18; BCL3; HIRA; MYCN; TBX3; TRPS1; ZNF500; TGFB1; MTA1; ZNF22; ZBED2; FLNA; HLF; ID4; MYCBP; GATA6; MEF2C; TFAP2A; ESR1; LEF1; ZIC1; PSMD9
Down-regulation	340	PARP1; USP22; PUF60; NR2F6; CDK7; HOXA5; SCAND1; ADNP; NFKBIA; CRK; HOXA10; SUZ12; SNW1; NFIL3; FHL2; HNRNPD; ATF1; SMARCA2; VEZF1; RFX5; TBP; NPAT; PRPF6; RBM14; CCNH; SFPQ; SUV39H1; MED17; EED; ZNF410; BRCA1; NUP62; CNOT1; BRD8; SP2; MYC; XBP1; TAF5; PQBP1; PSMC3IP; ZZZ3; PPRC1; VDR; TLE1; CBX3; REST; CEBPZ; PHF20; E2F3; BHLHE40; CTBP2; FOXO3; AIP; RBL1; FOSL2; CCNA2; KAT7; HIF1A; TAF5L; RNF111; CBFB; HOXA7; UBE3A; AFF1; PRDM4; AATF; ZNF146; CHAF1B; RBM39; FOXC1; TRIM32; TSC22D2; CHD1; GMEB2; VGLL4; TRIM27; BCL10; NRIP1; ZSCAN16; ZNF84; NCOA6; ELF5; HOXA11; ERG; FOXJ3; SMARCE1; HOXA4; GMEB1; IKBKAP; TSC22D4; ZMYM2; SAP30; TAF12; PCGF1; CTCF; TAF1D; ZNF672; RELA; ZMYND8; IRX4; BRD3; ZHX3; GTF2F1; CENPF; SAP130; RBBP8; HOXC6; WWC1; COPS5; ZNF443; BATF; ZBTB11; ZNF217; CEBPG; TADA2A; TRIM28; SAFB2; PAX8; BCOR; CIZ1; CTR9; SIRT7; ZBTB7A; TAF4; RNF138; ANKRD1; CCNC; ZNF473; ECD; MED1; NLK; DPF2; SIM2; BRPF1; NR1H2; BIRC2; HTATIP2; REXO4; ING1; ZNF239; UBE2B; DYRK1B; ZSCAN12; MTF2; PATZ1; GABPB1; PRKDC; ITGB3BP; ZNF593; TEAD4; RNF4; CDC5L; PPARGC1A; CXXC1; LMCD1; TCF20; AGO2; BRD7; RAD21; MGA; BLM; ZFP36L2; KDM2A; FOXK2; BTAF1; RBBP4; HOXB9; YWHAB; RARA; LHX1; TGIF2; ZNF200; NRBF2; ZFP30; ETV4; TAF7; FOS; NFYB; JUND; OLIG2; ZHX2; BCLAF1; TFCP2L1; MED27; E2F8; ZNF557; TBL1XR1; SIN3B; LYL1; ZBTB24; POU4F1; ORC2; JUNB; ZFP64; CCDC59; KDM5B; ZNF430; ELF1; THAP1; TCERG1; ZNF263; PREB; ZNF45; LPIN2; SMAD7; ERBB2; CAMTA1; PAX5; YEATS4; PMS1; ING3; YAF2; KAT8; ASH2L; RREB1; RNF14; MED13; CNOT6; DNMT3B; MTDH; WDHD1; MED23; NR2F2; SOX4; TBL1X; ZNF232; EDF1; RNF6; SMARCA5; MNT; RAN; MLX; ZBED4; NFYC; MED7; ZNF281; ZMIZ1; PIAS2; KDM4C; NR1I2; RFXANK; ZBED1; CITED1; PTRF; BAZ1A; SALL1; TRIM29; TRIM33; DDX54; BTG1; ZBTB1; GATAD2A; ZNF302; ZNF7; IRF5; ATF4; MAFG; MXI1; MYT1L; HOXA1; NFATC3; ZNF629; MED6; LIMD1; ZNF266; NR2C1; BAZ2B; THAP4; KLF6; RCOR1; SMAD2; CREB3L2; CREB5; PSPC1; ENO1; HMGB2; ZNF140; RBBP7; ASXL1; HOXB6; CBX5; PCGF2; CREB3; CEBPB; WT1; DDX5; ZNF432; BRD4; TTF1; CREB3L1; XRCC6; DLX2; AEBP1; ZBTB18; BATF3; GATA4; EGR3; TMF1; MBD2; BANP; HOXD10; FOXO1; NFATC1; TOB1; ARNTL; SOX9; SMAD1; SPEN; HDAC1; ELK3; ZFP36L1; DAXX; ZNF91; SATB2; MLXIP; BASP1; ID3; HOXC10; CRY1; IRX5; ABL1; IRF7; DMTF1; NR3C2; FOSL1; UBE2I; DACH1; TCF7L2; MAFF; ASCL1; ZNF165; HMGA2; NCOR2; PDLIM1; ZBTB38; ZNF331; MAF; MYBL1; THAP11; MAFB