Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID53667 Letrozole GSE92742 HA1E Human 24h 10uM EID0261
Types Number Response transcription factors
Up-regulation 24 GATA3; EPAS1; FOXC1; ZEB1; NCOA1; CARHSP1; KLF2; TWIST1; JUNB; MED1; PURA; ID2; TCF7; RUNX1; BRD2; MECOM; ZBTB38; KLF9; NR1D2; ASCL1; CREB1; WWTR1; MKL2; ID1
Down-regulation 24 CCNH; THAP10; ARL2BP; HOXD1; MED17; ZHX2; ZNF593; TBL1XR1; ZFPM2; ZNF83; TRIB3; ZBTB16; KAT2B; IFI16; ZSCAN18; ARNT2; ZBED2; ZBTB20; IRF9; HDAC9; MNDA; BHLHE41; ZBTB18; E2F2