Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID53532	Mitoxantrone	GSE92742	HA1E	Human	24h	10uM	EID0260

Response Information :

Types	Number	Response transcription factors
Up-regulation	195	XBP1; MED14; ZNF562; AR; ZNF43; NFE2L2; NR1H2; TWIST1; IRF8; VGLL1; TRPS1; ST18; WDR77; ZNF117; AEBP1; KDM5C; SOX17; WT1; ZNF532; TFAP2A; ZNF268; NFE2L3; HLX; TCEA2; HOXD1; TTF2; SRCAP; HOXB1; CERS6; ZNF816; CDK2; ZFPM2; RBPJL; NR4A1; TSHZ2; ZNF768; KLF7; PBX2; CSDE1; NR4A2; RSF1; ZNF141; ZNF586; ZNF654; IRF6; HDAC9; KAT2B; SOX18; ZNF354A; MEIS1; IRF9; MEIS2; ZNF264; HIF3A; ZNF224; ZNF331; SSBP2; CUX2; GBX1; L3MBTL1; SPDEF; SOHLH2; ZNF180; EHF; EP300; SPI1; ZBED2; ZNF551; TCF21; TAL1; ZNF205; CREB1; ZNF467; ZEB1; HMBOX1; TGFB1; ERBB4; MED12; CREB3L2; LEF1; SIX6; EMX2; KLF13; ZNF589; HIPK1; HIPK2; TCF3; MED25; KLF9; HSF1; ID4; MEF2C; TAF5L; INSR; CREBL2; SUPT3H; DLX5; SUPT4H1; ARL2BP; FOXJ1; ZNF671; GTF2I; ZNF711; MAK; FOS; ZNF195; ESR1; SOX11; PAX6; ATN1; TULP3; REL; FUBP1; SREBF2; RARG; TRIB3; MNDA; GATA1; PRRX1; ELK4; URI1; HBP1; TDP2; FOSB; CDIP1; ZNF611; INSM1; NFAT5; EHMT2; SHOX2; ZNF273; HIRA; MXD1; CREM; PEG3; ZSCAN18; HOXB5; TAF9B; SIX3; NEUROD1; SOX2; PBX3; CEBPD; VPS72; TCEA1; HOXB13; NR5A2; DACH1; AES; ZNF93; NFIX; ZNF124; ARNT2; ZNF22; IFI16; PBXIP1; PRDM1; RBFOX2; PBX1; CBFA2T3; SALL2; PHIP; BHLHE41; VDR; MECOM; CITED2; NR4A3; HEY1; TXNIP; ESRRG; THAP4; HOXD3; GRHL2; SP110; ZNF91; ZNF512B; BCL6; MDM2; MYCL; BCL11A; MYCN; CD3D; OLIG2; MYB; HES1; ID3; TCF4; AHR; EPAS1; NFATC3; ATF3; FOXN3; ID1; MTA1; NR2F1
Down-regulation	327	PUF60; FHL2; SCAND1; NFIL3; NFKBIA; USP22; CCNA2; HOXA10; FOXO3; ATF1; RBM14; MYC; HOXA5; FOXJ3; NUP62; CDK7; NRIP1; EZH2; SUV39H1; ZMYM2; ABL1; TBP; TP53; TLE1; PHF20; FOSL1; EED; KAT5; ADNP; BRPF1; ZFP64; BRD8; NR2F6; CTR9; KAT7; TCFL5; RELA; ERBB2; BHLHE40; TRIM32; BRD3; DNMT3B; ECD; BASP1; ELK1; HOXA11; RNF4; KAT6A; VEZF1; SNW1; SMARCD2; TRIM16; ZBTB24; TRIM28; CARM1; TAF10; TBPL1; ZNF267; EDF1; BRCA1; ZNF212; KDM2A; NRBF2; AIP; UBE2I; TRAK1; MED7; BLM; SFPQ; CHD1; RBBP7; SOX4; ARNTL; ZBTB11; SIRT7; HNRNPD; ASXL1; SMAD7; ZNF335; SIX2; PAX8; BATF3; CCDC59; HOXC6; KLF10; TGIF1; CHD8; BCOR; NCOA6; KDM5B; HSF2; REST; DPF2; PRPF6; CRY1; ZMIZ2; MNT; ORC2; BCL10; YAF2; BMI1; AATF; KMT2A; VGLL4; RBM39; MTF2; NR2F2; APEX1; HOXC10; CEBPZ; ITGB3BP; ELF1; CREB3L1; CENPB; HOXA7; CNOT1; UIMC1; ZNF292; CXXC1; NFRKB; DNAJC2; MLX; SMAD2; RNF111; KDM5D; TSC22D2; TEAD4; PSPC1; IRF4; MEOX1; ZNF408; ZNF263; MED1; RBBP4; PCGF1; JUN; NFKB1; ZNF16; PTTG1; ING3; MED6; ING2; ZNF410; ZNF443; MGA; PIAS2; SAP30; CASZ1; NCOA4; TCERG1; CBFB; SMAD3; TAF5; MED4; ZNF282; MKL1; PIR; SETD2; RBL1; NRF1; SMARCA4; RBPMS; RAN; HCFC2; MED27; NFKBIB; CHAF1B; STAT6; SNIP1; NCOR2; SERTAD2; TFCP2; JARID2; TSC22D3; JUND; SFMBT1; PLAGL2; CTCF; PATZ1; PPRC1; PCGF2; DDX54; C1D; ZBTB7A; RBBP5; BATF; SIX1; HOXB7; SMARCE1; FOXC1; NPAT; BCLAF1; BANP; SMARCD3; ZNF574; HDAC1; TAF4; TBL1X; ZNF143; NELFB; PREB; TLE4; KLF12; ZNF189; TSC22D4; ID2; NKX3-1; E2F6; TAF1D; CNOT2; LOXL2; MSC; EZH1; TBL1XR1; BTG1; SP140; HOXD10; ZNF202; SOX15; GABPB1; PMF1; USF2; DEK; MED17; CBX3; POLR2A; DDIT3; PSMC3IP; HMGB2; SUZ12; DMTF1; TRIM27; CENPF; HTATIP2; ZNF266; NEDD8; YWHAB; ASH2L; MYT1L; BRF2; ATF4; MAFF; HSBP1; PRRX2; CITED1; FOSL2; NKRF; MEF2A; CRYM; KLF6; ZNF45; DNAJC1; MITF; MED24; KLF2; RCOR1; TAF9; NFYB; HOXD11; SOX9; CIZ1; TCF12; BAZ1A; CTBP2; POU2AF1; RUNX3; SMARCA5; OSR2; RARA; RELB; MBD2; ZFP36L1; LIMD1; ING1; HMGB3; SF1; HLTF; RREB1; HOXB6; NR1H3; RBPJ; IRF2; BIRC2; ZNF672; ANKRD1; MAF; FOXD1; ZFHX4; MKL2; MEOX2; TCF25; HOXC4; ARID4B; ELF3; EGR2; LPIN2; ZBTB38; CEBPB; RUVBL2; CRK; ZBTB1; PITX1; FLNA; PITX2; BCL3; CDYL; PTRF; ZEB2; SMAD1; LMCD1; MAGED1; CEBPG; TOB1; ZBTB18; SIAH2; AFF1; SALL1; RUNX1; TRIP6; IKBKAP; RXRA; TBX3; TRIM29; ISL1; ZBTB20; ADRB2; NR3C1