Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID53200	Mexiletine	GSE92742	HA1E	Human	6h	10uM	EID0259

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	SSBP2; CREM; MED7; ARRB1; WT1; TOPORS; CD3D; TXNIP; MAX; ZFY; TBL1X; REL; MAF; TFDP2; MTF1; ASCL1; TCF21; EGR4; ZNF528; MYB; HOXC10; ZNF217; IRX5; ZNF337; CBFA2T3; BAZ1B; SMARCD3; CDK8; EHF; PPARG; NAB2; ZNF331; HOXB1; NR3C1; TFAP2C; CIITA; FOXD1; LZTS1; STAT2; MXD1; NR2F1; SPDEF; ING2; RBPJ; ISL1; MNT; TAF5; WHSC1L1; EGR2; E2F2; SATB1; SOHLH2; THRAP3; NR4A3; NONO; SHOX2; KAT8; DNMT3B; CITED1; NSD1; ZNF117; PKNOX2; IFNB1; GLI3; ZNF529; NKX2-1; AR; ESR1; AEBP1; NFIC; ZNF552; BCL10; CBX2; RELB; LHX6; MED21; TCF7L2; CTCF; ADNP2; SATB2; ADNP; SIX2; YBX2; THAP11; SSRP1; KAT7; EZH1; TWIST1; ELF5; DDX17; EGR3; ZBTB18; URI1; STAT5A; PURA; VGLL1; BARX1; PRDM1; TAF12; CCNE1; ASH2L; SIM2; TRRAP; MDM4; KDM5D; NFATC4; C1D; BCL11B; HOXA1; RARG; CTR9; RSF1; HMGB2; NEUROD1; HLTF; TFE3; NRBF2; TRIM33; NCOA4; FOXF1; MKL2; TERF2; RERE; NFYC; GATA3; TRIM25; PITX2; ZNF165; TBP; XBP1; MDM2; TAF1A; SSBP3; GATA4; NKX3-2; NCOA2; DPF2; PLAGL1; SMARCA5; TCEB2; SOX2; EMX2; POU4F1; ZBTB16; AFF4; RUNX3; GTF2I; ELF3; SAFB2; DLX2; SOX4; NR4A2; BHLHE41; RORA; SAP30; TGFB1; HMGB3; ZNF43; STAT4; CITED2; RBPMS; TSC22D3; ID4; CTNNB1; NCOA1; BHLHE40; MXI1; HOXB2; TRIP6; HEY1; EYA2; KLF10; DLX5; MNDA; TSC22D1; SMAD1; SMARCA2; ECD; HOXC6; IKZF1
Down-regulation	211	LOXL2; SCAND1; ATF5; PRDM4; USP16; STAT1; WWC1; ZMIZ1; HIRA; MED15; TRIM29; DAXX; ZNF446; DMTF1; APBB1; MNAT1; SPEN; ZNF140; ZNF74; ATF4; ARID5B; PTRF; ZMYM2; HDAC7; TCF3; IKBKAP; CIC; DACH1; ZNF512B; SALL1; MYOG; CRY1; ELF1; MYT1; TAF1D; NRIP1; KLF5; SRCAP; TFEB; TCF15; FOXF2; RBM39; ERF; THAP10; LZTR1; NCOA6; CREB3; NFRKB; ING1; ZNF646; BIRC2; ERBB4; BTAF1; PRDM10; MYRF; ERBB2; CHD1; ZNF202; TRIM32; KDM5C; ZNF84; BCL3; HCFC2; ANKRD1; SIX1; TRAK1; NCOR2; SLC2A4RG; HIVEP1; ARID4B; ZSCAN5A; PBRM1; SMARCB1; ELK3; PATZ1; ZNF551; GLI1; REPIN1; YAP1; CNOT1; CREB5; FUBP1; APEX1; ZNF135; CEBPZ; MTF2; ZNF536; SIRT2; CREB3L2; BRCA2; BPTF; CNOT3; CREB1; PAWR; PSPC1; HMX1; THAP7; ZMYND11; ZFP36L2; MED24; PAXBP1; TLE1; TCEA1; SMAD3; SETD2; CAMTA1; KMT2A; RFX5; CNOT2; MLXIPL; ETV6; SIRT7; AGO2; ZSCAN16; KAT6B; POU2AF1; KDM4C; ASXL1; ZNF45; ZNF232; BAZ2B; FOXC1; BCLAF1; LEF1; AIP; MED17; NPAS2; FOS; MEF2A; CTBP1; RXRB; NFIB; E2F8; FOXM1; JUP; ZNF580; NPAT; PBX3; IRF9; ID1; HMGA1; IRF8; RING1; MEIS1; MED23; NKX3-1; ERG; CREBZF; BRD2; ZBTB38; ZNF12; JUNB; TAF10; LMCD1; PHF1; TSC22D4; FOXN3; VEZF1; HIVEP2; ZNF384; PHF20; EGR1; GTF3A; NKX2-2; HMGB1; DEK; TGIF2; TGFB1I1; ZNF189; CDYL; BRD3; WHSC1; ACTL6A; ID3; TEAD4; HDGF; FOXO1; TBX3; KLF13; MED14; ZNF652; PPARGC1A; LITAF; INSR; PA2G4; TOX3; CEBPB; ZNF91; ZNF423; TGIF1; CENPB; NR1D2; TAF7; ZSCAN18; SMAD7; MAGED1; SOX17; CREB3L1; MEOX1; TSC22D2; IRF1; TCF4; ST18; BASP1; CHD9; YBX3; MTA1; TOX; MAFB; TOB1; MSX1