Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID53111	Chlorthalidone	GSE92742	HA1E	Human	6h	10uM	EID0259

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	ZNF506; MAF; EGR2; ZNF217; HEY2; KLF2; FOXF1; ZNF350; FOSB; NR4A1; ADNP; KLF9; NFAT5; ELF3; CBX7; EGR3; ZSCAN18; AHR; KMT2B; NFIC; PRRX1; NPAT; CHD3; MEF2C; MYCN; SKI; AR; TFCP2L1; TMF1; CTR9; ATF7IP; HSF2; HDAC5; ZBTB43; NR4A2; TRIP6; DDX17; HLX; FLNA; ZFP64; HOXC10; PFDN5; ZBTB18; RNF6; HIPK1; CENPF; LPIN2; HOXB5; MSC; NEDD8; EYA2; CCNE1; ZNF532; HEY1; RERE; BCLAF1; RBPMS; ZNF331; FOXD1; ZNF443; AFF1; KLF4; BHLHE41; MITF; SMARCA2; TLE4; NR1D2; NFATC1; TRPS1; ASCL1; MKL2; NCOA4; HOXB2; ASH2L; HTATIP2; EMX2; TOB1; TBPL1; MAFB; ZNF274; TSC22D3; MEOX2; ARID4B; RUNX1; NCOA2; ESR1; MEIS1; ATF3; AEBP1; HHEX
Down-regulation	65	DAXX; GATA6; ZMIZ1; E2F5; TRIM29; POU2AF1; ZNF23; DMTF1; ZNF232; WNT4; ZNF711; CTBP1; BANP; ERBB2; CEBPZ; USP21; E2F8; DACH1; ZNF202; HIRA; ZNF410; TOX3; CDYL; CAMTA1; SIX2; ATF4; PAWR; ZFP69B; TOX; RFX5; RBBP4; IRF9; CUX1; RBM39; HMGN3; IFI16; MYBL1; CERS6; KLF5; EHMT2; RNF14; CREB1; SPIB; TEAD4; IRF8; VGLL4; APEX1; VEZF1; RAD21; MTA1; CTBP2; PEX2; ZNF195; KAT6B; HOXD1; MXI1; IRF6; BASP1; ZNF91; NR2F1; FOXE1; ID1; SOX11; PDLIM1; TFAP2A