Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID52006 Mexiletine GSE92742 HA1E Human 24h 10uM EID0254
Types Number Response transcription factors
Up-regulation 19 GATA3; PFDN5; MEIS2; KMT2A; DBP; ESR1; ZMIZ2; TRPS1; CREB3L2; ING3; NR2F2; MBD2; SERTAD2; NR3C2; TBL1X; KDM5D; KLF6; RXRA; ZNF91
Down-regulation 17 TBL1XR1; RAN; SOHLH2; PAXBP1; ZIC1; NKX2-2; CENPB; NCOA4; IRF7; DLX2; CRY1; SMAD7; BHLHE41; SOX11; PAX5; MYBL1; WT1