Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID51547	Tramadol	GSE92742	HA1E	Human	6h	10uM	EID0252

Response Information :

Types	Number	Response transcription factors
Up-regulation	357	MXD1; NR1H2; E2F2; ZNF227; GATA3; BRWD1; CEBPD; ZNF695; SSBP2; HOXC5; SOX13; TBP; IKZF2; FOXL2; PGR; POU1F1; ZNF225; ZNF835; SOX18; LPIN2; ZNF571; TBX1; NR1H4; ZBTB3; SOX17; ZNF157; ZNF80; TFAP2B; HR; CREM; ZNF480; IKZF3; SKIL; ZNF440; ASCL2; RNF141; MAFK; PITX1; PAX4; ZNF492; ZNF816; ZNF674; ZNF701; AFF4; KMT2D; GATA2; EPAS1; RFX1; ZNF75D; ZNF552; WNT4; TAF12; TAF7L; MAK; ZNF780B; BCL11B; WWP1; ZNF180; TRIM25; ZNF236; FOXJ1; PKNOX1; ZKSCAN8; PRDM10; FOXE1; ZNF787; PLAG1; ZNF507; ZNF550; WHSC1L1; ZNF432; ZBTB6; ZNF234; PIAS2; ZBTB24; BRIP1; ZHX3; ZNF253; ZNF226; MAFG; NCOA1; ZNF254; NANOG; DOT1L; MNT; POU4F2; ZNF93; SSX1; LIMD1; NKX2-1; ZBTB7C; LIN28A; ZNF391; GATA4; BRCA2; ZNF675; MLLT1; ZNF471; TFCP2L1; GABPA; POU2F3; SAFB; FOXD3; ZNF214; JUP; ZNF688; ZNF407; ZNF41; STAT2; RCOR1; BRDT; BCOR; ZHX2; ZBTB25; TAF5; MEOX2; MNDA; ZNF682; ZNF136; ZNF331; CEBPG; FOSL2; CARF; PITX2; PML; SKI; HIPK3; NKX2-2; TOX; KLF3; ZNF155; PAX7; ZNF423; DNAJC1; GCM2; ZIM2; NFE2L3; ZNF549; ZNF442; ZNF460; RUNX3; ZNF557; PIR; NEUROD1; CD3D; RORA; SCRT1; JAK2; TMF1; PEG3; VHL; ZNF749; ZNF81; PAX5; HOXC6; TRIM33; ZNF528; GFI1B; POU6F1; SOX3; ZNF132; CBFA2T3; ZNF516; TSC22D1; ZFY; ZNF354A; ZNF205; TRPS1; MED31; E4F1; TAF1D; MAF; PRDM5; PRKDC; ZFP69B; ZNF141; MSC; ZNF329; PAX9; TDRD3; SOX21; ZBTB16; SOX1; HNF4G; ZNF764; ZNF257; TULP4; SAP18; ZNF510; CBX8; NCOA2; YAF2; SAP30; BARX2; POU3F1; SMARCA2; SP4; ZFP30; INSM1; TAL1; NFE2; CCNT1; ZNF85; ZNF83; MAFB; VGLL1; NCOA3; HIPK2; ZNF45; HMG20A; MNX1; NR4A1; PBX2; FOXN2; CBX5; ZNF529; ZBTB20; ZNF135; CIITA; ZNF74; BNC1; HLX; KMT2A; TBX21; ZSCAN32; SMARCA5; ZEB2; ZNF107; SMARCA1; DMRT1; RARG; EGR4; ZNF273; RBPMS; OSR2; STAT4; ZBTB44; FOXJ2; CDIP1; TAF9B; NRBF2; ZNF200; CTNNB1; ZNF222; CHD2; ING2; ELK4; EMX2; SHOX; ZNF667; PLAGL1; AGO2; ELF3; AEBP1; KAT6A; HDAC2; WDHD1; HCFC1; ZNF10; CAMTA2; TOPORS; ZNF813; IFI16; ZNF467; SMAD2; RARA; PFDN5; HSF2; EP300; RSF1; FOXA2; NFIX; SIM1; BHLHE41; SPDEF; ZNF443; CBX7; ANKRD1; TCF20; HMGN3; MECOM; CREBZF; ZNF551; POLR2A; NFAT5; SMARCE1; ZNF587; MYBL1; MLXIP; ELK3; POU2AF1; IL16; FOXG1; HIC2; TCEB2; MAFF; EGR3; WT1; SREBF1; SNAI2; PRMT2; HMGB3; RYBP; YBX2; ZBTB39; ZNF350; PKNOX2; CUX2; ETS2; MTF2; HOXD1; ZNF91; NR3C2; CBX6; STAT5A; SUPT5H; JUN; LZTS1; ZNF32; NR2E1; MYB; NPAS2; ZNF304; ZFPM2; ZNF532; TEAD1; NPAT; ZNF430; GATA6; EN1; ISL1; CEBPB; ZFHX3; PRDM1; DAXX; MITF; TXNIP; TRIM28; BATF; ST18; TBL1XR1; ZFP36L2; KLF9; CREG1; ZNF274; PSMC3; ZNF264; VDR; EHF; TBPL1; MKL2; KDM5A; ZSCAN18; TP53; HOXC10; KDM5D; ABL1
Down-regulation	406	HOXA5; RFX5; TRIP6; TAF9; SMARCA4; STAT6; THAP11; THAP4; APEX1; LOXL2; NUP62; WWC1; ETV4; ACTL6A; DEK; ATF6; PBX3; ATF5; IKBKAP; WWTR1; GTF2IRD1; CCNC; ATF1; FOXF2; CDYL; ERCC3; GMNN; DLX2; ARNTL2; ZNF589; DEAF1; CDC5L; GTF2A2; PTTG1; TAF10; HOXA4; PBX1; MDFI; ARID5A; TCEA2; TRIM16; ATF2; TFAM; RBM39; RFC1; DNAJC2; MED13; TAF6; CBFB; CRYM; TEAD4; THAP3; TUB; USP16; WIZ; RNF4; BLM; COPS2; MYC; SUPT4H1; NKX3-1; REPIN1; ID3; PRDM4; FOXO3; VEZF1; ATF4; ERCC2; CRY1; ITGB3BP; SUMO1; TOX4; SNW1; SFPQ; MLX; HLTF; COPS5; SF1; MAX; HDAC3; UBE2L3; SMAD6; CDX2; RAN; ZNF562; SLC2A4RG; PRRX2; SMARCD1; SERTAD2; MGA; ZNF12; HOXB13; HABP4; CENPF; SUB1; BATF3; FOXP3; NFKBIA; MAZ; TCF3; MED21; MBD4; KDM2A; CHD1; ZNF217; EWSR1; PTRF; CHD9; ZNF7; HOXA7; SATB2; ZNF189; C1QBP; ZNF652; ZNF426; CHD7; MED6; ZNF668; HOXA10; HOXB3; TRIM29; BCLAF1; TBX10; MYOG; BIRC2; ZKSCAN3; RNF2; ZNF250; CBX3; MZF1; MED27; KAT7; HDAC4; MED20; RFXANK; NELFB; ZKSCAN1; CEBPZ; ZFHX4; NKRF; SCMH1; ZEB1; MAP3K10; NR3C1; JUNB; TFDP1; GBX2; NFRKB; PAXBP1; ZFP64; POLR3F; ILF2; KAT8; RBPJL; PEX2; LITAF; TRAF6; BAZ1B; ZNF783; CSDE1; ASXL1; USP21; SP140L; VPS72; PMS1; PMF1; CREB3; CENPB; ARID4A; ZNF408; PSMC3IP; GLI3; MTDH; XRCC6; MED25; SP140; CASZ1; ZMIZ1; KAT6B; TFCP2; ZMIZ2; ING3; TSG101; TDP2; SETDB1; KAT2B; HOXB5; BNC2; MEN1; VGLL4; TCERG1; RBBP8; EDF1; PCGF1; ZBTB11; CCNE1; UBP1; ZNF384; NRIP1; TGIF2; NOCT; ARNT; NCOA4; RBFOX2; SREBF2; ELF1; SIRT7; FOXJ3; BTAF1; MLXIPL; CTR9; HMX1; CITED1; EHMT2; ATN1; SUPT3H; TERF2; THRAP3; FUBP1; PLAGL2; TADA3; FOSB; HINFP; MED4; ZNF646; SMAD1; ZNF133; HOXB6; MLLT10; TRIM27; SIM2; MYRF; CREB5; ZNF512B; ZSCAN12; MTA1; REXO4; RRN3; BLZF1; ID2; SIX2; ZBTB38; FOXF1; STAT5B; ZBTB32; BRD4; SOX9; DLX4; SIX1; TAF11; ABT1; HOXB2; SP100; TSC22D4; SETD3; TAF5L; ZNF219; HDAC7; NFIC; HMBOX1; SUPT6H; MEF2D; SOX12; BCL11A; MED24; ZNF593; SMAD3; TAF7; ZNF335; TFAP4; TRAK1; APBB1; PEX14; KDM5B; KLF2; SNAPC4; MXI1; HOXA3; SMARCC2; SFMBT1; DMTF1; ZNF16; BMI1; ERBB2; SMAD7; TCF7L2; PHF8; CUX1; TP63; ZMYM2; ACTL6B; ZNF140; PRPF6; ARID5B; TFAP2C; FOSL1; ZNF444; MYT1; TOX3; HMGA1; GMEB2; ENY2; SMAD4; SRCAP; HIPK1; SOX4; HDGF; TRIB3; HBP1; PA2G4; MED1; PPARGC1A; ZNF232; EGR1; CTBP1; HNRNPD; ID1; FOXI1; BRD8; PDLIM1; ETV1; SOX2; TFEB; FOS; HDAC9; PREB; ZNF580; E2F6; E2F3; ZNF672; ENO1; NR1D2; NAB1; KLF10; ZZZ3; RUNX1; TGFB1; DNMT3B; HIRA; ZSCAN31; IKZF5; ZBTB1; KLF7; PPARG; PCGF2; ZNF266; YAP1; TOB1; BCL6; LDB1; STAT3; STAT1; C1D; FOXM1; PHOX2A; TULP3; NFE2L1; ARID4B; PHF1; CARM1; RAD21; TSC22D2; ARL2BP; FLNA; SCAND1; HOXB7; REST; CREB1; AR; CNBP; BRD3; KLF5; NFKB2; FOXN3; HSF1; YWHAB; FOXC1; BAZ2B; BASP1; ZBED2; KLF6; TGFB1I1; PHF20; IRF9; MEIS1; CAMTA1; ID4; CALR; NEDD8; NCOA6; CREB3L2; PATZ1; DACH1; AHR; MSX1; NR2F2; DDIT3; MYCBP; TFEC; IRF8; JARID2; MNAT1; NR4A2; ZBTB18; MEIS2; TBX2