Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID51546	Tolbutamide	GSE92742	HA1E	Human	6h	10uM	EID0252

Response Information :

Types	Number	Response transcription factors
Up-regulation	309	CREM; NFATC3; NR1H2; CEBPD; GATA3; RNF141; NFKB2; SSBP2; BRWD1; HR; LIN28A; DNAJC1; PKNOX1; ZNF571; MXD1; NANOG; TAF12; FOXE1; EPAS1; SOX13; STAT2; NKX2-1; HIPK3; ZBTB3; PITX1; ZNF225; SOX3; ZNF695; SP1; KLF3; SSBP3; KLF4; ZNF331; DDX17; SMARCA5; ZBTB20; SOX18; TCF21; TBX1; CBX7; RFX2; NR4A1; JUP; KAT2B; NR4A3; EYA1; GATA2; TFAP2B; CBFA2T3; EGR3; ING2; CUX2; IKZF2; BCOR; POU6F1; ZNF440; FOSL2; ZNF227; PBXIP1; ZNF236; BCL11B; DNMT3B; VGLL4; ZNF80; ZNF157; GTF2I; TRIM25; POU1F1; ZNF701; SSX1; MAFK; ZNF492; ZKSCAN8; AFF4; ZBTB24; LPIN2; TRIM33; WHSC1L1; FOXJ1; PGR; ZHX2; CREBZF; EGR4; TRIP11; KDM5B; HHEX; NCOA1; ZNF226; PIR; NFE2; SOX21; ZBTB25; RFX7; EHMT1; E4F1; LIMD1; SREBF1; ZNF423; BARX2; OSR2; ZNF214; ZNF257; MAFB; HLX; RSF1; STAT4; ZNF75D; ASCL2; TAF7L; PIAS2; NEUROD1; RORA; CDK9; TCF12; HMBOX1; ZNF407; ZNF141; NR1H4; SP4; EYA3; TBL1X; SKI; ZNF10; BRDT; HMGB3; CUX1; POU5F1B; AEBP1; BRIP1; SIM1; PHIP; MAK; POU2F3; HIC2; GABPA; ZNF132; BNC1; UBTF; KMT2A; EP300; ZNF286A; ZBTB16; ZNF254; CARF; CARHSP1; TWIST1; HIC1; SMARCA1; NAB2; RBPMS; ARRB1; MYCN; ZNF432; YBX2; ZNF79; ZNF623; IKZF3; NR2C2; ZNF529; NFIX; ZNF205; ZNF460; PRMT2; MED12; CNOT6; ZNF682; NCOA3; NFYA; POLR2A; BRPF1; ZNF688; AFF1; ELK4; ZBTB39; ZNF33B; BACH2; ZNF557; PLAG1; PLAGL1; RXRA; MAFG; CTBP2; EGR2; ZIM2; PRKDC; REL; HEY2; SIX2; ZNF671; HDAC7; EMX2; MYBL1; MEIS1; MEF2C; NLK; ASH2L; ZFP36L2; HOXA11; TAF1D; ZBTB6; SAP130; CDIP1; TFDP2; AGO2; FLI1; ZNF692; RARG; MYBL2; BHLHE41; MDM4; DMRT1; ZNF443; NRBF2; NONO; GATA4; TFE3; TXNIP; MKL2; HDAC6; ZNF532; NFKB1; TERF1; TFAP2C; PEG3; HTATIP2; SAFB; RARA; KLF10; PRDM1; LZTS1; HLF; ING4; ZNF350; BMI1; WT1; NPAT; MYOD1; NFIC; MXD4; ZXDC; MEF2A; NR5A2; RCOR1; CALCOCO1; ZFY; YAP1; LHX2; MAF; ING1; PIAS1; SOHLH2; MLXIP; IRF6; NFKBIB; ISL1; ZNF500; GFI1B; FLNA; RERE; NKX2-2; ZNF3; TCEB2; REST; ZNF329; PURA; PSMC3; PPP1R13L; ELK3; CHD4; TCF7L1; IRF7; GATA1; ZNF516; ATF7IP; RUNX3; SMAD2; TULP4; MDM2; BBX; DDX5; MAGED1; NFAT5; SMAD3; MAFF; CTNNB1; CD3D; ESR1; ZNF721; FOXG1; PRRX1; GABPB1; ENO1; OLIG2; ERG; NR2F1; MECOM; AR; ZNF274; NPAS2; ZNF117; SMAD1; MBD2; TBPL1; KDM5D; TRPS1; ZNF281; NR4A2; TBX3; ABL1
Down-regulation	385	PSIP1; APEX1; HOXA5; DNMT1; LOXL2; NUP62; TRIP6; ATF6; THAP11; RFX5; C1QBP; IKBKAP; ATF5; TFAM; RBM39; ATF2; HOXA4; DEAF1; ARID5A; CCNC; GTF2IRD1; RFXANK; CDC5L; DLX2; TUB; RRN3; DEK; BRD4; WWC1; GMNN; ZNF12; CRY1; MDFI; TAF9; CHD7; GTF2A2; COPS5; ARNTL2; ZNF446; GCFC2; TRIM29; BATF3; MAX; SUB1; MYC; CHD1; ZNF562; ZNF668; USP21; REPIN1; CBX3; THAP3; CITED1; FOXO3; STAT6; ARID4A; PRDM4; NFRKB; NFKBIA; SERTAD2; RNF4; YBX3; ZFP64; TAF10; HOXB1; CCNA2; SATB2; ERCC3; NFIB; RFC1; PBX3; CBFB; MED27; ETV4; NKRF; E2F3; USP16; UBE3A; TCF3; ZNF426; HMGA1; CSDE1; ING3; NKX3-1; TAF11; WWTR1; ZNF580; FOXF2; SFPQ; RAD21; TRIM27; SMARCD3; DNAJC2; ZNF468; GATAD2A; RNF2; KDM2A; PCGF1; HDAC3; BTAF1; UBE2L3; ATF6B; ABT1; GATA6; MAZ; PTRF; ZNF189; ZNF22; SNW1; TDP2; THAP4; C1D; KLF5; SRCAP; MTDH; WIZ; SOX12; ZBED4; KAT2A; MTF2; SF1; ZFHX4; TBX10; ZNF473; COPS2; ERCC2; URI1; RNF138; ZNF195; PBX1; ZNF217; SUPT4H1; CDYL; CREB5; HIVEP1; SMARCB1; CDX2; SCMH1; MED1; HES1; ELF1; BCL3; TEAD4; UBP1; TBX6; SP100; ATF4; ZNF444; SP140; HDGF; GBX2; TLE2; MED13; ZNF783; BAZ1A; HOXA7; VEZF1; HOXD1; FOXP3; ZNF202; RXRB; RBBP8; CERS6; TRIM16; MNAT1; PATZ1; MGA; ZNF512B; FOXJ3; RUNX1; FOXM1; GTF3A; ZNF232; BIRC2; SOX9; KLF11; CEBPE; CCDC59; TERF2; RNF10; ZNF131; ZNF7; ACTL6B; TRAF6; AIP; PAXBP1; ZNF408; CARM1; TP63; ZNF45; SPEN; ZFP30; TGIF2; NRIP1; MXI1; MYNN; EHMT2; RAN; RREB1; KAT6B; MED21; E2F5; ZMIZ1; NAB1; ZNF574; HLTF; MYRF; TRIB3; CCNE1; BRD2; CBX4; NFYC; TOX4; ZNF133; HINFP; ZBTB11; BAZ1B; PHF20; RNF14; BNC2; TEAD3; RLF; TCERG1; MED25; TRAK1; MZF1; ZSCAN12; MED24; ARNTL; ZNF593; LMCD1; BRD8; MYT1; RBFOX2; TGS1; BCLAF1; ASXL1; TAF5L; ILF2; ID2; MEOX1; HOXA3; MED4; POU3F2; MLX; HOXB3; ZMIZ2; ARID5B; ZNF324; ID3; NOCT; SFMBT1; ZNF146; SALL1; FUBP1; TSG101; PLAGL2; TAF4; MTA1; HABP4; YWHAB; HOXC4; NCOA6; PTTG1; CHD9; NHLH2; SOX15; NEDD8; ZZZ3; SP140L; MED16; SIX1; SPIB; CAMTA1; GMEB2; TCF7L2; UIMC1; CTR9; ZNF587; HOXD3; ATF3; SUPT3H; FOS; E2F4; ZNF8; ZMYND8; CNBP; PPRC1; ZNF24; ARNT2; FOXN3; SCAND1; DACH1; HOXB13; CREB3L2; ETV6; E2F1; BLM; SPI1; SP3; ERBB2; E2F8; ZNF83; ZMYM2; ZBTB38; SSRP1; CNOT3; ZNF652; ARID4B; MLXIPL; ZNF43; MSX1; RING1; TADA3; DMTF1; TAF7; TP53; TGIF1; FOSB; RXRG; PHF1; CHD8; ZNF175; BCL11A; STAT3; IRF9; CTBP1; BTF3; NR3C1; SHOX2; HOXB5; PDLIM1; SOX10; CRYM; PMS1; PPARG; FOXO1; ADNP; MNDA; STAT1; PMF1; INSM1; CREG1; RELA; ZNF140; BCL6; NR2F2; SMARCA2; ITGB3BP; IRX5; KAT8; HIRA; PBX2; TCF4; RNF6; NELFB; XRCC6; TCEA1; CREB1; CNOT2; MYCL; ZBED2; HMGXB4; TCFL5; FOXD1; IRF8; TGFB1I1; HNRNPD; HSF1; ID1; SOX11; ELF5; CALR; FOXF1; POU2AF1; NR1H3; SRF; DDIT3; HOXB7; TOX3; DAXX; MEIS2; EYA2; HOXB6; MYCBP