Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID51425	Glipizide	GSE92742	HA1E	Human	6h	10uM	EID0252

Response Information :

Types	Number	Response transcription factors
Up-regulation	323	SSBP3; NR1H2; SOX2; KLF3; SOX3; LIN28A; SOX13; ZNF136; IRF4; NANOG; SNAI2; JAK2; ZIC3; THAP7; BRD4; ZNF148; MXD1; ZNF701; TERF1; NFIX; SOX21; KLF4; ZBTB44; TWIST1; EGR2; NFATC4; RFX2; ARRB1; IKZF2; MECP2; BNC2; NFE2; ZXDC; IL16; IRF6; POU5F1B; HOXB1; CIITA; KAT7; NLK; NCOA2; CBFA2T3; EYA3; ZNF669; TRIB3; ZNF93; SLC2A4RG; ZNF415; WHSC1L1; EZH1; KLF7; BRD2; SMARCA1; ZNF257; HOXA2; TXNIP; CCNH; MBD1; ZKSCAN8; RARG; SPDEF; TGFB1; NCOA3; MED12; TRIM22; KAT6A; BBX; NFIC; OVOL1; ZNF408; ZIM2; RFX3; PRDM14; ZNF132; SPIB; CDIP1; IFNB1; NFATC3; HDAC9; TBL1X; NAB2; KMT2D; ZNF552; TOX3; LHX3; KLF13; LPIN2; ZBTB20; CBX7; ZBED2; NFE2L3; EGR3; ZNF334; CD3D; SRY; CARHSP1; TRIM25; PEG3; PIR; ZNF391; ZNF337; ZNF350; ZNF467; KDM5C; PIAS3; THRB; INSM1; HEY1; HIC2; TBX1; ZNF586; TAF4B; E2F2; FOXE1; KLF15; TFE3; BRDT; ZBTB3; ASH2L; ZNF667; ZNF711; RSF1; FOXG1; NFKB2; HCFC1; UBTF; STAT2; NFE2L2; CASZ1; GRHL2; FOXH1; NFKBIB; EPAS1; KDM5B; NR2F1; MED20; CHD3; ZNF682; CCNT1; ZNF160; CHD2; PAX1; PPARD; SIX3; ZNF665; IKZF1; TRIM33; ZNF764; ETS1; DEAF1; ZNF117; ARID3B; SP2; ST18; SHOX; DDX17; MYT1L; BCL11B; GTF2I; ZNF154; OVOL2; PLAGL1; MTF1; ADNP; ZNF589; ZNF253; PITX1; PRDM12; ATF3; ZNF611; SIAH2; NOCT; NEUROD1; ZNF135; SMARCB1; BAZ2A; VPS72; SP4; DNMT3B; KLF6; GLI2; RERE; ZNF331; KAT2B; WWP1; SSX1; CBX5; CEBPD; BARX1; RELA; ZFY; ZNF778; TAF4; VGLL1; RING1; TCF7L1; NR2C2; SUPT4H1; MEF2C; PAX2; PRDM1; ZNF329; SOX5; IRF8; TOPORS; FOXO3; YBX2; VDR; MED14; ASH1L; ID4; WIZ; ZNF282; MDM4; HMGB3; ZNF506; HMG20A; RBPMS; TCF7; FOXA2; DLX4; AR; FOXJ1; PRRX1; TOB1; CBX6; ZNF587; ABT1; SMARCA5; ZNF44; POLR3C; ZNF165; MYBL2; ZBTB24; SUPT6H; HOXC4; KMT2A; E4F1; KDM5D; ATN1; GFI1B; ZNF528; ZNF562; HIPK2; EGR1; CUX2; SNAI1; SKIL; CREM; WT1; HOXB2; HOXB5; MXI1; PHF8; FOXJ2; PGR; ATF7IP; MDM2; SALL2; ZNF652; MKL2; CIR1; NR4A2; MYBL1; STAT5A; ZFPM2; PPARG; CALCOCO1; IRF5; RBL2; PIAS1; ZNF721; ASCL1; KLF1; ZNF124; ZNF544; E2F5; CHD4; HLF; TFDP2; FOXO4; LHX2; GATA1; EGR4; LZTS1; KLF9; PBX2; NPAT; MYCL; PAX6; RBPJ; OSR2; PNRC1; HMBOX1; SKI; CTR9; MAFF; ZNF304; ZNF274; NFATC1; TAL1; NFAT5; PRKDC; BCL11A; RUNX3; FOXD1; TFEC; AEBP1; HOXB6; FOXF1; BTG1; CTNNB1; ZSCAN18; CALR; KDM5A; EMX2; HOXC10; FOXO1; SAP30; TLE4; DAXX; SATB1; TBX2
Down-regulation	340	LOXL2; HOXA5; TLE1; ZNF410; FHL2; DNMT1; RFX5; IKBKAP; APEX1; BCL3; ATF5; BRD8; ZFX; CRY1; SETD2; WWTR1; GTF3A; RBM39; CCNC; WWC1; ARID5A; HOXA4; EDF1; ZNF446; ZNF302; PSPC1; ZNF45; BRCA2; ERG; MED6; ERCC3; BASP1; FOXJ3; KAT6B; MED17; NFYB; ELK3; RCOR1; PMS1; YBX3; MTF2; RFXANK; ZNF131; ZMIZ1; CBX3; HOXA7; BLM; FUBP1; SNW1; UBE3A; HMGN3; PHF1; RBL1; MED27; MYOG; ZNF146; ATF2; ATF4; SAFB2; ELF1; MEIS1; VGLL4; SAP18; NFIB; HSF2; RNF138; TRAK1; ERCC2; CHD1; GCFC2; PATZ1; STAT6; TCF15; RNF6; SF1; TRIM16; BRD3; RBBP5; PHF2; ZNF646; ING3; MLLT10; REXO4; SMAD3; TFAM; PTTG1; MED21; SFPQ; SIX2; MSL3; SETD3; CEBPB; ZKSCAN5; TERF2; HOXD13; BIRC2; ZNF250; PRDM4; NKX3-1; ZNF593; ARID4A; ID3; VSX1; RYBP; PAXBP1; BMI1; THAP10; IKZF5; NKRF; RUVBL2; PHF20; NFKB1; TTF1; RNF10; PCGF1; ZMYM2; ZNF227; ZFP30; ZNF239; NRIP1; SIX5; ZNF12; ZNF468; HLTF; SOX10; ZSCAN12; ZNF32; TRIM32; BATF3; ERBB2; MYF5; RFXAP; NR2C1; MED4; NRF1; TLX2; HTATIP2; ZNF22; SUPT3H; CHD7; KMT2B; ARID5B; ARNTL2; WDHD1; ORC2; NPAS2; RBBP8; NR2F2; SUMO1; DLX2; TAF10; ZNF580; ZBTB11; PITX2; TRIM29; GABPA; PSMC3IP; RLF; DEK; MTA1; MLX; TFEB; HOXA10; TCEA2; ZNF292; PRRX2; DNAJC1; ZNF354A; APBB1; TCF3; ETV4; MEF2D; TRIP6; CBFB; RUNX1; TDRD3; USF2; CRYM; MDFI; KMT5A; SP110; KLF5; SP140L; USP16; NCOA6; NCOA4; ZMIZ2; PCGF2; HMGA2; MLXIPL; BRIP1; ID2; SFMBT1; ZNF35; TSC22D4; DACH1; ANKRD1; ZNF219; CNOT6; PHOX2B; SIRT2; ZBTB1; CDK8; GMEB2; KDM2A; USP21; ITGB3BP; SALL1; HIVEP1; RXRB; SRCAP; PAX5; TAF1A; FOS; SMAD6; TMF1; HOXD11; TBL1XR1; TLE2; NAB1; ZMYND11; HDAC4; MEF2A; STAT3; CNBP; CEBPG; ING1; TAF6; CENPF; ZNF23; ZNF358; DMTF1; WHSC1; ARID4B; CDC5L; MYNN; SNIP1; REPIN1; UBE2L3; CHAF1B; INSR; BAZ1A; SIM2; E2F6; CREB5; COPS2; PQBP1; SIRT7; ZNF107; ZZZ3; HMGB1; ZNF16; NEDD8; ZNF536; STAT1; FOXC1; ZNF226; RBFOX2; PDLIM1; PHOX2A; HMGB2; PTRF; RXRG; IFI16; RBBP4; HOXC6; REST; RCOR3; RBM14; BACH2; SERTAD2; ZBTB43; ZNF267; ZNF248; YAF2; CUX1; POU2AF1; TGFB1I1; UIMC1; PPARGC1A; SCAND1; HOXD1; MAGED1; HCFC2; GATA6; ZNF423; ZEB2; HEY2; CREG1; ZSCAN31; MECOM; ETS2; YEATS2; AIP; SOX9; MGA; TBX3; POU4F1; BAZ2B; HOXD3; CTBP1; CHD8; TSC22D1; ARNT2; UBP1; MED1; MED24; MBD2; PBRM1; ZNF211; BCL6; KAT8; NCOR2; HNRNPD; HMGA1; ZNF83; TCEB2; CCDC59; SREBF1; DDIT3; XRCC6; TCF7L2; ABL1; SUB1; CREB1; ZFP36L2; SMAD7; JARID2; TP63; MTDH; SMAD2; LEF1; TOX; IRF7; ZBTB18; GATA2; HBP1; HIRA; MAFB; MNAT1