Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID51132	Dactinomycin	GSE92742	HA1E	Human	24h	10uM	EID0251

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	ZNF264; ZNF611; INSM1; ZNF816; ZNF665; ARL2BP; ZNF160; HSF1; TDP2; NR2F1; FOXA2; ZNF586; ZNF239; ZNF345; ERBB4; SALL2; STAT4; NFATC3; SP140L; HIRA; MEIS2; TCEA2; SOX13; SPDEF; ZNF467; ETV1; AR; HOXB13; ZNF154; THRB; WT1; THRA; VPS72; PEG3; ZNF136; ING4; ZNF44; ZNF444; CAPN15; VGLL1; ZNF415; ZNF721; LHX3; CREM; PEX14; CDIP1; NR0B2; SOX2; ST18; TRIB3; LIN28A; TBX1; ATN1; ZNF544; NHLH2; ZNF562; MEIS1; ZBTB17; CREBL2; ZNF91; ZHX2; LEF1; SIX3; TGFB1; ZNF224; ETS1; PRDM14; WNT4; IRF8; ZNF573; ZNF688; TSHZ2; RORC; ZNF232; NANOG; TCF7; SNAI2; RAD21; ZNF350; BCL11A; MDM2; ZNF117; BNC1; MECP2; NR5A2; HMBOX1; SUMO1; KDM5C; ZNF701; MNDA; CEBPD; CBFA2T3; ZNF528; ZNF768; ZNF551; L3MBTL1; PBX1; CDX1; BCL11B; AEBP1; TCF21; ZNF304; NFE2L3; RING1; ZBED2; FOXJ1; CUX2; ZNF83; HIPK2; FOXF2; CERS6; HOXD1; WDR77; HLX; HIPK1; ZFPM2; KLF7; ARID3B; NR2E1; ZKSCAN1; TAF11; IRF6; LDB1; ZNF623; SOX11; PAX6; FUBP1; SSBP3; NKX2-2; PRRX1; FOXF1; ZNF93; DACH1; CD3D; RARG; EPAS1; SOX17; RBFOX2; PTRF; CNBP; TRPS1; TFAP2A; HTATIP2; REL; GATA1; TCEB2; DLX5; AHR; SLC2A4RG; ARNT2; TULP3; ZNF43; ACTL6A; KLF3; ZNF195; INSR; FOS; CTBP1; CTNNB1; KAT2B; HMGB3; MECOM; EHF; PHIP; ZNF652; NEUROD1; ATF5; ZNF423; IFI16; LITAF; SMARCA1; CREB1; PBX3; MYRF; ID4; ARID5B
Down-regulation	357	HOXA5; NFKBIA; VGLL4; CCNA2; MYC; FHL2; HOXA10; SCAND1; FOXO3; KAT6A; ID2; NCOR2; USP22; BHLHE40; TLE1; ASXL1; SOX4; NUP62; ABL1; BRD2; PATZ1; SUV39H1; EED; HDAC2; CEBPZ; EZH2; TBP; FOSL2; CCDC59; TRIM32; KDM2A; NPAT; BRPF1; RBM14; ING2; ZNF282; BCOR; PSPC1; NFIL3; PLAGL2; ADNP; CHAF1B; KAT5; MED4; ZNF248; SAP30; TAF1D; XBP1; SMAD7; VEZF1; FOXJ3; ATF4; ZBTB1; YAF2; GABPB1; BCLAF1; KAT7; DPF2; ZNF672; SMARCA2; WDHD1; POLR2A; SETD2; ZNF292; PHF20; MED6; TOB1; TCF12; PTTG1; HSF2; RBBP4; SP2; SFMBT1; ING1; USF2; HCFC2; NR3C1; MGA; SMAD2; NKX3-1; SMARCD3; SMARCA5; MED23; ASH2L; HMGB2; TMF1; HOXA7; PRPF6; RCOR1; ZBTB11; STAT5B; PCGF2; PUF60; THAP1; HOXC6; ZNF212; ZNF263; MLX; RELB; DR1; NCOA6; ARID4A; ATF1; MAGED1; CHD1; RNF111; RNF6; ZBTB24; SFPQ; BRD8; CTR9; RBBP7; ZFP64; RARA; EDF1; TRIM27; NEDD8; RELA; USP16; KDM5A; E2F8; TAF5; MAFF; TBPL1; AATF; ZBTB18; FOSL1; BRD3; SMARCE1; TADA2A; UBTF; PURA; BLM; MED1; TBL1XR1; WHSC1; NFE2L1; THAP11; ZNF202; ZBTB14; RFX7; SMAD1; ZNF410; ELF1; BTAF1; UBE2I; APEX1; MMS19; HNRNPD; CNOT1; KLF10; PPRC1; KDM5B; RREB1; HLTF; ZFP30; SIRT7; TBX3; CDK7; SNW1; MTF2; ZMYM2; BRCA1; THRAP3; COPS2; BCL10; TSC22D2; AFF1; SP140; RNF4; KLF12; ECD; PQBP1; MBD2; EGR3; NRBF2; PMF1; ELK1; NCOA4; CCNC; DDX54; MNT; DNMT3B; ORC2; KMT2A; CREB3L2; TRIM33; ZNF574; RBL1; ERF; TCFL5; LIMD1; STAT3; PAX8; JUNB; CRY1; ADNP2; SNIP1; ARNTL; HMGXB4; ZNF267; CCNE1; HOXD10; NRF1; ZMIZ2; PBRM1; TRIP4; REST; PRKDC; MEF2A; HIVEP2; NRIP1; JUN; PIAS2; ELK3; POU2AF1; RXRB; BATF3; ANKRD1; UBE3A; FOXD1; TCF20; TDRD3; NR2F2; SREBF1; IRF4; TFCP2; ZNF84; ARID4B; FOXK2; DDX17; TOPORS; PIAS1; KLF2; KLF6; BAZ1A; ZNF227; CENPF; SND1; EGR2; MAFB; PPARGC1A; ZNF189; ZNF45; TULP4; POU4F1; NFIB; NFKB1; BAZ1B; NCOR1; ELF5; HOXB6; TRIM16; BCL3; SMAD4; BATF; LMCD1; ELF3; CREB3; ZHX3; ZNF576; NLK; TAF4; SIX1; CHD8; ZNF143; FOXC1; ZNF146; TRIM28; ING3; BRIP1; KMT5A; EGR1; ARRB1; MNAT1; CHD4; ATF7IP; SIAH2; RBM39; HMG20A; HOXA11; NAB1; NCOA1; ZEB2; TERF2; ZNF443; FOXJ2; OSR2; NFATC1; MITF; DNAJC2; MEOX1; SATB2; LPIN2; EP400; SERTAD2; MAX; KAT6B; KMT2B; TSG101; ZNF266; TRIP11; PHF8; ZNF629; MSC; AIP; DNAJC1; JARID2; PCGF1; KAT8; ZNF217; CITED1; NR4A1; CBFB; HDAC4; TFCP2L1; PITX2; HOXB7; MAF; TAF10; FLNA; DEK; KLF4; ZBTB16; DEAF1; SAFB; EYA2; SUB1; MED17; PLAGL1; STAT1; MSX1; RBPJ; KLF5; NR1H3; NCOA2; NR3C2; IRF7; WWTR1; RUNX1; TSC22D4; SOX15; NKX2-1; HOXC10; CTBP2; BMI1; SMAD3; FOSB; RUNX3; HES1; FOXN3; SOX10; TRIM24; TFAP2C; TSC22D1; SOX9; DMTF1