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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID50871 Dactinomycin GSE92742 HA1E Human 24h 10uM EID0250
Types Number Response transcription factors
Up-regulation 183 ZNF586; IRF1; SOX2; SOX13; PRDM12; ZNF91; INSM1; HLX; SALL2; THRA; NR5A2; AES; NFE2L2; HOXB1; SOX3; ZNF580; NR2F1; CNOT3; HIRA; TCEA2; PEX14; RAX; ZNF44; MECOM; ZNF688; ZNF76; HSF4; ZNF264; ZNF665; WDR77; ZNF768; ZNF544; SPDEF; CD3D; ZNF93; ZNF136; RORC; MED25; GTF3A; ZNF219; ZNF611; ARL2BP; E2F4; HOXC4; MECP2; HIPK2; SNAI2; ZNF589; GBX1; RING1; CDIP1; TCF21; FOXF2; CBX4; HIF3A; PRDM14; ZNF562; PAX6; MEIS2; TDP2; NFATC4; ZNF131; ZNF671; NFIC; SIX6; NFIX; ZNF140; CUX2; ZNF43; ZNF816; ZNF358; LHX3; NKX2-2; IRF6; ATN1; LDB1; HSF1; CAPN15; BRD4; NHLH2; ZNF174; VGLL1; PRMT2; ZFPM2; TFE3; RBFOX2; KDM5C; CITED2; PBX1; CBFA2T3; ZNF667; SUPT6H; CDX1; HEY2; ZNF195; ZNF117; GBX2; KLF13; PRRX1; ZNF500; PHIP; REL; NEUROD1; TTF2; INSR; GTF2I; SPI1; EP300; ZNF224; PTRF; ZNF415; DACH1; AR; SIX3; WNT4; PEG3; SUMO1; LIN28A; HMBOX1; ZNF273; SMARCC2; PEX2; TGFB1; IRF8; TAF11; CREBL2; ZNF467; ERBB4; ZKSCAN1; ZNF528; TOX; ZNF12; ID4; CALR; SLC2A4RG; SUV39H1; SP140L; CREM; ETS1; CSDE1; ZNF32; HOXD1; ZNF304; ZNF512B; NANOG; SOHLH2; TCF7L1; BNC2; ZNF551; HBP1; MDM2; RAD21; CREB1; HIC2; CBX6; MEIS1; ZNF274; PNRC1; RBPMS; TRPS1; EPAS1; ZHX2; ZNF83; CTBP1; TRIP6; ARNT2; C1QBP; ZNF652; SALL1; MNDA; ARID1A; PPARD; NR4A2; FOXF1; FOS; AEBP1; ZBED2; ZIC1; ZSCAN18; HEY1; WT1; PBX3; SOX11
Down-regulation 299 TLE1; NFKBIA; NFIL3; NRIP1; MYC; HOXA5; FHL2; USP22; TBP; FOXO3; FOXJ3; CCNA2; XBP1; HOXA10; UBE2I; AGO2; ASXL1; PHF20; CNOT1; CDK7; CTR9; PLAGL2; NR3C1; SAP30; KAT5; RNF111; SOX4; ZNF146; TAF4; PUF60; EZH2; BRD3; AATF; SMARCA5; TAF1D; ABL1; CREB3; PATZ1; TCERG1; KDM5B; TRIM32; EED; BRPF1; CCNH; MED6; SMAD7; NPAT; SNIP1; TULP4; ATF1; YAF2; ELF1; RELB; TSC22D2; ANKRD1; SETD2; KDM5A; VEZF1; NCOA6; KAT6A; BTAF1; TFCP2L1; SMARCD2; ELK3; RHOA; REST; AFF1; MGA; GMEB2; ARID5B; UBE2B; PAX8; DPF2; BCL10; SFPQ; ZNF189; KMT2B; FOSL1; SP3; ADNP2; BLM; CENPF; EP400; TCFL5; TRIM27; ZBTB11; RBM14; VGLL4; HOXC6; NKX3-1; CCNE1; ZNF217; NFIB; PRPF6; RCOR1; SNW1; JUNB; NFKB1; ADNP; CHAF1B; WDHD1; KLF2; BCOR; BRD8; MLX; HABP4; PSPC1; LIMD1; FOXJ2; SCAND1; RBBP4; CCDC59; ING1; MEF2A; CHD1; E2F3; NAB1; LPIN2; USP16; ARID4B; ELF3; NEDD8; TBL1XR1; ERCC3; ZFP30; KMT2A; RNF138; ZNF143; CEBPZ; RARA; PCGF2; EDF1; ZFP64; TOX4; NCOR2; CRY1; TCF12; HIVEP2; MMS19; MED27; FOXK2; TERF2; KAT7; DNMT3B; SND1; NCOA4; SIAH2; TOPORS; SMAD2; CEBPG; UBE3A; AIP; ITGB3BP; RBM39; MTF2; PRDM4; ETV4; ZNF292; TMF1; IRF4; PPRC1; BRCA1; TRIM28; ZNF212; POLR2A; PBRM1; HIVEP1; USF2; MYCN; BATF; MAFF; GABPB1; RUNX1; ING3; MBD2; ZNF282; BACH1; HCFC2; PMS1; BATF3; CXXC1; ZNF384; CDYL; HNRNPD; TSC22D1; ASH2L; ID2; TRIP11; BIRC2; ZMIZ2; ATF4; RUVBL2; POU4F1; ZBTB1; TBPL1; ZMIZ1; BHLHE40; SMAD3; SERTAD2; SREBF1; ZSCAN12; MAGED1; E2F8; PURA; RYBP; ZFP36L2; EGR1; PTTG1; ECD; ING2; ZNF267; ZNF263; IRF7; KDM2A; KLF10; DMTF1; ZNF672; ZNF443; ZNF45; LMCD1; TOB1; KLF6; ORC2; HDAC2; STAT1; STAT3; TAF10; DNAJC2; APEX1; JUN; RREB1; PIAS1; RELA; ZFHX3; ERG; NRBF2; BAZ1A; VDR; RBL1; TSC22D4; ZBED1; SMARCA2; DEAF1; SIX1; MED1; JUND; CEBPB; HLTF; CTBP2; FOXD1; MED17; FOXC1; FOSL2; CREB3L2; SOX9; TRIM16; BHLHE41; CBFB; PHOX2B; STAT6; PIAS2; NR3C2; BAZ2B; ARNTL; RBBP5; OSR2; EGR3; SFMBT1; MED23; TSC22D3; JARID2; ZBTB20; MAF; BCLAF1; HDAC4; IKBKAP; CARHSP1; ZFX; FLNA; CUX1; MAFB; HMGB2; ZBTB18; SPEN; RBPJ; MNAT1; CRK; IRX5; TFCP2; TBL1X; HOXB7; ID3; BRD2; POU2AF1; NR2F2; PIR; DLX2; ADRB2; E2F2
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