Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50768	Tc-2559	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	304	E2F2; SOX2; NR1H2; TP73; ZNF688; GLI2; TCF21; PRDM14; SUPT3H; NFATC4; NCOA3; HES1; POU6F2; VENTX; POU4F3; DNMT1; BNC1; KLF13; PROP1; BNC2; AIRE; BACH2; SCRT1; GATA1; LHX3; TBX5; ZNF816; ATOH1; HOXB1; TAF5L; CDIP1; POLR3C; HIRA; IFI16; FOXF2; SKIL; SOX17; ZNF180; ILF2; FEZF2; THRB; BARX1; ESRRB; RING1; HEYL; FOXN1; GFI1B; JUN; ZNF682; NEUROD1; ZHX2; AEBP1; ZNF654; ZIC3; MAP3K10; RB1; GRIP1; ZNF74; MED25; KLF15; TEF; DDIT3; HSF4; LIN28A; ABT1; TLX3; ZNF154; VPS72; ZNF132; SALL2; ZNF195; MED20; CDX4; ETV3; CBX2; MEIS2; ZSCAN18; ZFPM2; NRL; ALX4; IRF6; SRCAP; WNT4; SOX14; TCEA1; ZNF141; NEUROG2; TCEA2; VAX2; KLF3; CHD2; OVOL2; NKX2-2; INSM1; TRIB3; NR5A1; RAD21; RARG; EN1; ZBTB7B; NKX6-1; PRRX1; ZNF701; TULP2; PRDM2; DEK; ZNF611; CBFA2T3; ZNF343; NKX3-2; FOXH1; RNF2; GBX1; NHLH1; THAP11; THRA; ZNF532; TAF6L; GMNN; ETV2; MED14; ZNF83; TUB; ZNF835; POU1F1; HOXD12; UBE3A; SNAI2; CSDC2; SOX21; MAPK8IP1; NFIX; SOX5; TULP3; CNBP; ZNF586; TDP2; ZNF695; HOXA4; NFE2L2; ZNF35; E4F1; PEG3; ARL2BP; ZNF667; DOT1L; VGLL1; TFAP2A; ALX3; PPARD; DLX5; HIPK1; PRMT2; ARID5A; ZNF423; NEUROD6; TBX1; SOX13; PGR; ZNF440; USP21; ATF6; CREM; HIC2; PIAS4; ZFP69B; KAT2B; ZEB1; PAX6; SOHLH2; ZNF43; ZNF573; FOXA2; CERS4; ARNT2; WDR77; ZNF665; WT1; OVOL1; KLF11; ZMIZ1; ATF5; TRPS1; PRDM12; SUMO1; HLX; ZFP36L2; KLF1; ZNF331; CAPN15; HOXD13; ZBTB16; ZNF576; TEAD3; ISL1; PAX5; SIRT7; PBXIP1; CDC5L; FOXI1; SPIB; NR0B2; TP63; MED31; CUX2; RXRG; TAL1; SPDEF; FOXJ1; TTF2; BCL11A; MEIS1; ZNF232; ZNF415; TBX21; TAF9; PCGF1; ZNF623; PITX2; ZNF93; NEUROD2; ZNF22; ZNF467; ACTL6B; TAF5; POU5F1B; HOXB13; SIX6; HIPK2; ZIC1; MECOM; MBD1; NANOG; RBFOX2; SIX3; ZNF239; ST18; HOXB5; BRD7; AR; NFE2; TRIP4; HSF1; FOXK2; IRF8; CNOT2; ZNF273; ZSCAN9; ACTL6A; PNRC1; IRF1; PAWR; ZNF500; SMARCD3; SATB1; ELF4; ZNF711; NHLH2; ERBB4; BCL6; VDR; HHEX; MYCN; NFIC; MDM2; ESRRG; TADA3; TCF4; TCF7L1; GTF2A2; YEATS4; HDAC9; HOXB2; SMARCA1; SP140L; E2F8; E2F5; TRIM22; CRYM; ZNF131; ID4; MYB; NR4A2; EHF; HOXD1; ID3; PBX3; MYBL1; TERF1; ZFP36L1; ID1; PBX1; RUNX1; TFAP2C; ZBED2; TRIM29; MYRF; KLF7; AHR; TGFB1; KLF5; GATA6; CITED2; INSR
Down-regulation	382	HMG20B; CRK; ERBB2; NFKBIA; TP53; FOXO3; FOXJ3; ARID4B; TSC22D2; USF2; ZNF212; FOXO4; RBM14; BRD8; KDM5B; HOXC6; SMARCA5; PSMD9; NUP62; DRAP1; TAF10; TRIM28; ATF1; DPF2; PHF8; SMARCA4; ITGB3BP; EDF1; REST; XBP1; MXD4; USP22; RHOA; NFIL3; NCOA6; KLF12; RBBP5; BRD3; ELK3; TBP; ZBTB11; TRIP6; NFYC; PHF20; PCGF2; AFF1; NEDD8; BAZ1A; PCBD1; ELK1; EP400; FHL2; SMAD3; HMGXB3; NCOA4; BAZ1B; CTR9; TBL1XR1; NR2F2; KAT7; EGR1; NPAT; AATF; FOXC1; ING1; MYBL2; ORC2; MTA1; BCL3; ZMIZ2; EZH2; DDX54; SNW1; SIX1; UBP1; TCERG1; SP110; PREB; HSF2; HOXC10; SETD3; MED6; SFPQ; MGA; NPM1; ZNF783; IRF2; NONO; TRRAP; KDM2A; POLR2A; NR3C1; BRCA1; LIMD1; HMGA1; ZFP64; GABPA; ZNF282; KAT5; KMT5A; NFKBIB; MYC; MAGED1; MED1; MBD2; IKBKAP; TRIM32; NSD1; RBBP4; RNF111; BATF; BMI1; SNIP1; ZNF14; SMARCD1; HCFC1; SP140; ZNF23; TEAD1; PDLIM1; ZNF587; SMARCC1; ELF1; MSX1; ZBTB38; TMF1; STAT5B; KLF6; HLF; TSC22D4; ZBTB14; SETD2; KAT6A; BCLAF1; SAP30; ZNF189; SMAD7; ADNP2; PAX8; TLE1; LPIN2; THAP1; TAF1D; KMT2A; TBL1X; PUF60; ZNF384; TTF1; PML; TCF7; ING3; PBRM1; BAZ2A; UBE2I; SPEN; HDAC4; FOXD1; CALCOCO1; BIRC2; PATZ1; SUPT5H; NRBF2; MXI1; TCF12; HOXB7; SERTAD2; CERS6; ZKSCAN1; CHD1; SND1; YAF2; GTF3A; HOXB3; SMAD2; GABPB1; BAZ2B; IRX5; BRF2; MEN1; MAFF; IRF4; ERCC3; HDAC7; FLNA; MNAT1; MTDH; SUZ12; SF1; PPARGC1A; REPIN1; NELFB; DNAJC1; TADA2A; ZMYND8; PAX2; HMG20A; HIPK3; BATF3; RFX7; ADNP; HNRNPD; MED23; YWHAB; ARID4A; SSRP1; SUPT6H; TRIM16; PIAS2; MAX; SIAH2; PTTG1; RFX5; BBX; YBX1; RNF10; NLK; SMAD1; ZNF200; NR3C2; MEF2D; RXRB; IRF5; JARID2; SALL1; MSC; ABL1; MAZ; MYOD1; ZNF419; SATB2; MTF1; SMARCA2; TFAM; ALX1; ZZZ3; ZNF292; KAT6B; STAT3; ZNF430; ZNF24; MMS19; ENO1; FOSL2; TAF4; MED13; PHF2; ATF7IP; HDAC6; RBL1; PSIP1; CCNE1; UIMC1; ZNF672; HMGN3; ZNF302; WWC1; ZNF432; RUVBL2; CUX1; HLTF; ASH2L; ZBTB40; POU3F2; ZNF226; E2F6; ETS2; LMCD1; CBFB; ID2; STAT6; ING2; MLX; ZNF148; MLXIPL; HOXC4; NR1H3; BASP1; NFIB; TOB1; SMAD6; SIM2; ERG; TCF20; RNF141; ELF2; NFAT5; ZEB2; IKZF5; MED24; SMAD4; CALR; PIR; HDAC1; PRPF6; ZBTB18; ZNF205; SLC2A4RG; ARID1A; BTAF1; CREB5; PA2G4; DNAJC2; ARRB1; SFMBT1; BLM; CENPF; CHD7; KLF2; RCOR1; ERF; NCOA1; ZNF589; KDM5A; SMARCC2; TRAK1; MEOX1; ZFHX3; SMARCE1; TCF15; ZNF263; MEF2A; ZBTB1; TFCP2; CBX3; COPS2; CITED1; ZNF580; SOX4; RERE; NCOR2; PKNOX1; RBPMS; BRD2; NFKB1; NKX3-1; ZBTB20; DAXX; GTF2I; RUNX3; SMARCD2; SIN3B; TSC22D1; PURA; ETV5; CARM1; VGLL4; CREBZF; HIVEP2; TOPORS; ZNF443; SUB1; STAT5A; NFATC1; EMX2; ZNF248; TFCP2L1; TULP4; POU2AF1; HSBP1; TGIF1; DEAF1; PRKDC; CREB3L2; SCAND1; RREB1; CNOT1; HTATIP2; NR1D2; STAT1; NFE2L1; HOXA10; SUV39H1; KDM5D; TXNIP; CREG1; FOSB; DNMT3B; ZNF91; HOXB6; GATA3; BHLHE41; IKZF1