Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50736	Ranolazine	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	159	E2F2; NR1H2; SOX2; DNMT1; TP73; ATOH1; SKIL; HOXB1; VENTX; MYCL; BARX1; ZNF141; FEZF2; CDIP1; SALL2; POU4F3; ZNF682; ZFP69B; ZNF257; ZNF180; ZNF74; NR5A1; GFI1B; ILF2; APEX1; ZNF688; IFI16; GMNN; POU1F1; DOT1L; ZIC3; ARID5A; NEUROG2; TCEA1; PITX2; E2F4; BNC2; MNDA; PRDM12; USP21; LIN28A; TRIB3; ST18; CERS4; RING1; ZNF124; ZNF3; ZNF93; ZNF576; SUPT3H; MDFI; IRF3; ARNT2; FOXA1; HIRA; SRCAP; WT1; PRDM10; PIAS4; ZNF467; PRDM14; SOX13; ZNF91; TAF6L; KLF3; SIX2; HOXD10; NEUROD1; EN1; ZFPM2; ZNF354A; POLR3C; HSF1; RBPJ; ZHX2; SSBP3; TEAD3; ZNF268; ZNF232; CUX2; TCF7L2; KLF13; ZNF43; ZBED4; NKX2-2; TDP2; TOX3; CEBPB; MEIS2; PBX2; ELF4; PAWR; CNBP; BCL6; TCF7L1; HIC2; FOXF2; HOXB2; ZNF623; VPS72; ZNF512B; CNOT3; TTF2; ZNF140; ZNF83; ZNF32; HOXD1; ARID1A; ZBTB16; SHOX2; FOXE1; TCF3; VGLL1; SOX17; NHLH2; AES; E2F5; NFE2L2; ARID5B; BTG1; SPDEF; ZFP36L2; TULP3; ZIC1; INSM1; MAFG; SNAI2; SP140L; SOX11; NFE2L3; KLF11; SIX3; PBXIP1; HLX; KDM5D; ZNF224; ZNF12; AEBP1; ATF3; RSF1; ZNF281; E2F8; ERBB4; IRF6; KLF7; GTF2A2; TLE4; INSR; ZFP36L1; BCL11A; GATA6; LITAF; MYRF; STAT4; ZNF423; MEIS1; CREB3L1; MAFB; ID3
Down-regulation	197	KDM5B; ELK1; ATF1; BRD8; BRPF1; FOXO4; ZFP64; BCLAF1; USF2; RNF111; KAT7; TBP; RHOA; ECD; PHF8; ZMIZ2; NCOA6; EP400; NFIL3; BRD3; EGR1; NPAT; ZBTB11; NFKBIB; CTR9; ZHX3; BMI1; DPF2; ZNF783; XBP1; FOXC1; STAT3; REST; ELK3; KLF12; RNF14; ZNF23; RBM14; UBP1; ELF1; FOXJ3; TBPL1; HSF2; NR3C1; KAT5; TCERG1; SMAD3; ZBTB43; NR2F2; RELB; AFF1; ZNF384; TRIM28; ING2; POLR2A; SFPQ; ZNF587; KDM2A; STAT5B; SIX1; FOXO3; AATF; TRRAP; NCOA4; BHLHE40; ORC2; BATF; TRAF6; ING3; KMT2A; PTTG1; NEDD8; DNAJC1; PPARGC1A; MGA; SETD3; ZBTB40; HOXC6; HMGA1; ABL1; ARID4A; SIAH2; EDF1; TMF1; SPEN; UIMC1; BLM; TSC22D4; SERTAD2; MNAT1; NFAT5; TCF12; RBL2; TCF7; MYOD1; TOB1; TGIF1; SMARCA4; YAF2; MSX1; E2F6; BIRC2; NELFB; SFMBT1; HLTF; CHD7; HMG20A; ETS1; PCGF2; IKZF5; SETD2; ZBTB38; ZNF292; BATF3; RNF10; ALX1; BAZ1B; LPIN2; ID2; MED6; PURA; SMAD2; NR3C2; MTDH; BAZ2B; KLF6; PTRF; ITGB3BP; BRD2; ASH2L; EZH2; KAT6B; BBX; NCOA1; IRF5; TXNIP; MBD2; MAX; BCL3; TULP4; KLF10; HIVEP2; ATF7IP; TRIM25; CBFB; STAT5A; HIPK3; ZNF443; MLLT10; RNF141; SUB1; JARID2; IRX5; IRF4; FOSL2; PIAS2; SMARCA2; HNRNPD; ZEB2; SMAD7; FOXD1; ENO1; TAF4; CHD1; SMAD5; ZBTB20; RERE; YWHAB; NR1D2; HTATIP2; MXI1; MED1; DNMT3B; ZNF589; ZMYND11; HDAC6; SOX4; NFIB; HOXC10; RBPMS; SATB2; PAX8; CREG1; TSC22D1; STAT1; JUNB; NR2F1; NFATC1; TERF2; HOXB7; KDM5A; POU2AF1; ZBTB18; KLF2; GATA3; SUV39H1; IKZF1