Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50729	Phenformin	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	189	ZNF195; SOX2; ZNF44; NR1H2; DNMT1; ZNF586; ZNF180; KLF13; BARX1; BNC2; ZNF701; CDIP1; SMARCB1; GMNN; ZNF816; TRIB3; ZNF611; SRCAP; SKIL; PEG3; ZNF665; ZHX2; ZNF3; ZNF264; ZNF688; TCEA2; ZNF74; ZNF91; ZNF467; VPS72; ZNF544; SUPT3H; IRF6; PIAS4; ARNT2; ZNF43; FEZF2; NKX2-1; BNC1; TDP2; BACH2; ZNF331; MED14; ZNF682; SALL2; IFI16; ZNF93; PRDM14; ZNF215; OVOL2; MNDA; ELF4; POLR3C; TCF7L2; YEATS2; PPARD; ARID5A; HSF1; TAF5; SSBP2; SOX13; FOXE1; ZNF141; ZNF562; E4F1; RING1; ZNF136; WNT4; RBFOX2; ZNF835; ZNF239; SOX17; LIN28A; TGS1; TEAD3; ZNF268; ST18; LHX3; ZIC3; ZMIZ1; PRDM10; RAD21; FOXF2; ZNF232; BRD4; ZNF623; MAK; AEBP1; TCEA1; NEUROD1; ZNF160; HIRA; ZFPM2; ZBED4; ZNF573; CNOT3; RBPJ; INSM1; CALR; MECOM; TULP3; HLX; TAL1; HDAC9; ZNF83; TCF7L1; HMGXB4; ZEB1; ZNF354A; OSR2; ENY2; AR; HIC2; TCF3; ZNF274; CBFA2T3; HIVEP1; PRDM2; E2F8; ZNF224; TTF2; ZNF281; HOXD1; RARG; ZNF117; ZNF12; NANOG; CRYM; ZNF415; SMARCA1; HMGB3; TERF1; HOXB2; ZSCAN18; ZBTB16; SPDEF; ID3; NFE2L2; ZNF500; ZNF22; CDK8; VDR; NKX2-2; SMARCD3; ZFHX3; CUX2; EN1; TP63; PRKDC; L3MBTL1; E2F5; SHOX2; KLF11; PBXIP1; PAWR; SOX11; GTF2A2; DDIT3; ARID5B; DLX5; CEBPG; HOXB13; KDM5D; ZNF512B; IRF8; KLF7; FOXO1; MEIS2; BCL11A; HOXB5; MYB; EMX2; COPS5; HHEX; CREB1; PBX1; NFE2L3; JUP; ATF3; ZBED1; TOX3; ZFP36L2; ZNF423; TRPS1; INSR; TFAP2C; ZFP36L1; ID1; NR4A2
Down-regulation	203	USF2; CRK; KDM5B; NFKBIA; BMI1; TP53; ATF1; NUP62; ZBTB11; BRPF1; FOXC1; ARID4B; MXD4; ELK3; NEDD8; ING1; FOXO4; BCLAF1; ZFP64; ZMIZ2; DRAP1; EDF1; TBP; RNF10; KLF12; ORC2; MYC; HOXC6; UBP1; TAF10; EGR1; SP140; BRD8; BATF; NR2F2; UBE2I; REST; SFPQ; CHD1; KDM2A; NCOA6; CTR9; NFKBIB; PREB; DPF2; IRX5; LIMD1; PSMD9; NPAT; HMGN3; PSMC3IP; GTF3A; STAT3; RBM14; NFIB; ELK1; SMARCA4; FOXO3; IRF4; YBX1; BRD3; POLR2A; ATF6; MAX; TOB1; MTF2; AFF1; SIAH2; NR3C1; TSC22D4; KAT7; LPIN2; SAP130; TSC22D2; ZNF516; EP400; ZBTB38; YAF2; CCNA2; BATF3; ZBTB14; RBBP4; HAND1; HLF; RNF14; BAZ2B; YWHAB; GATAD2A; NCOA4; ALX1; ATF7IP; SMAD3; HNRNPD; RELB; AATF; E2F2; STAT5B; ZNF410; HSF2; SPEN; ELF1; ING3; RELA; RNF4; MSX1; SUB1; PHOX2A; RFX7; KLF6; CTBP1; ZEB2; BBX; HLTF; HIPK3; PPARGC1A; SMARCE1; SNW1; BIRC2; MXI1; DNAJC1; RFX5; ZBTB18; MSC; CXXC1; MLX; NCOA1; ETV5; KLF2; MED1; NFYC; BLM; ZNF589; DMTF1; HTATIP2; BAZ1A; TXNIP; PCGF2; IKZF5; FOSL2; SMAD6; BHLHE40; FLNA; PHF20; FOSB; PURA; PTRF; EN2; ARID4A; CBX3; TRIP6; FOS; MED6; SMAD2; CBFB; SMARCA2; WWTR1; HOXA11; SERTAD2; NFKB1; TRIM32; BRD2; SFMBT1; VGLL4; SMAD5; MEOX1; PIAS2; TBL1XR1; NCOR2; HOXC10; MITF; EGR3; PBRM1; LMCD1; KDM5A; MTDH; FOXD1; ID2; NFAT5; STAT5A; CARHSP1; HDAC6; HMBOX1; SIM2; MAGED1; JARID2; AIP; NFATC1; CRY1; CITED1; RCOR1; ERG; ZNF24; NR2F1; SOX10; CREG1; ELF5; SMARCD2; TSC22D1; NR1D2; SUV39H1; MAFB; GATA3; IKZF1