Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50718	Podophyllotoxin	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	252	NR1H2; SOX2; ZNF44; SKIL; DNMT1; ZFPM2; ZNF682; HES1; ZIC3; ZNF43; KLF3; CREM; ZNF141; ZNF667; ZNF180; NEUROD1; BNC2; ZNF254; SALL2; LIN28A; CDIP1; TAF1A; ST18; ZNF93; VENTX; FEZF2; ZNF816; ZNF124; HIC2; INSM1; ZNF135; ZNF214; TP73; BNC1; LHX3; ZNF749; ZNF223; PRDM14; IRF6; ZNF195; ZNF334; NOCT; ZSCAN18; ZNF701; GMNN; ZNF117; TDP2; ZNF257; SUPT3H; KLF13; CHD2; ZNF665; ZNF154; JUN; ELF4; ZFP69B; FOXF2; CBFA2T3; ZNF611; ZNF835; POU1F1; ZNF91; MDM4; ZNF695; PAX4; BARX1; ZHX2; NHLH2; NKX2-2; ZNF654; SCAI; ARNT2; THRB; MED14; ABT1; HDAC9; HIRA; ARID5A; ZNF492; WDR77; PIAS4; ZNF675; NFATC4; JUP; CUX2; ATOH1; ZNF467; TGIF2; ZNF268; ZNF329; TCF7; SPI1; GLI2; RING1; SOX3; EN1; ZNF551; SOX17; THAP11; RRN3; RBFOX2; SAP18; TRIB3; TCF21; HLX; ZNF273; SRCAP; ZNF22; RBBP5; CERS4; ZNF345; PRRX1; WT1; TBX1; TCEA2; E2F4; RAD21; ZNF415; ZNF426; AFF2; CDK2; ZNF85; ZIC1; ZNF711; PEG3; RB1; HOXD13; ZNF239; AEBP1; ARNTL2; SOX13; VPS72; TCF7L2; SSBP3; ZNF215; NR1H4; STAT2; MAK; ZNF573; ZNF432; ZNF136; ZNF83; NR5A2; CDX1; ZNF544; ZNF74; ARID5B; ZNF423; ZBED4; ZBED2; ZBTB16; SHOX2; ZNF264; BACH2; MEIS2; ZNF529; CDYL; CNBP; PRDM10; POLR3C; CALR; ZNF331; ZNF562; GLI3; NANOG; PAX5; SPIB; RARG; SOHLH2; HSF1; ZMIZ1; PAX6; TAF4B; TAF9; CAPN15; PHIP; ZNF281; TCF7L1; NFE2L2; HHEX; TCF3; MNDA; PBXIP1; ZEB1; VGLL1; HBP1; PCGF1; MEOX2; MECOM; ZSCAN9; TOX; CSDE1; ZNF304; PBX2; OVOL2; SNAI2; CCNT1; HOXD1; ZNF12; ZNF232; YEATS4; CDK8; ZNF160; E2F5; ERBB4; BCL11A; BACH1; GATA6; ZNF500; SPDEF; TGFB1I1; AES; NR4A3; WWP1; SOX11; CDC5L; MYBL1; TWIST1; FOXA1; IFI16; ZNF165; TOX3; AR; HOXB2; PHF1; ZNF274; NFE2; LITAF; L3MBTL1; KLF7; FOXA2; HOXB13; E2F8; ATF3; ACTL6B; TERF1; CEBPB; TULP3; TRPS1; EHF; INSR; MEOX1; ATN1; GTF2A2; PPARD; EMX2; PBX1; NR4A2; SUV39H1; ID4; TGFB1; TXNIP
Down-regulation	288	HOXA5; NUP62; NFKBIA; KDM5B; FOXJ3; TP53; PUF60; FHL2; ERBB2; TBP; ATF1; USF2; DPF2; ZFP64; NCOA6; NPAT; NFIL3; BRD8; BRPF1; ARID4B; HOXC6; TBPL1; RHOA; RBM14; EP400; TRRAP; FOXO3; NEDD8; XBP1; ZBTB11; ECD; ZNF783; MAGED1; BATF; BRD3; TLE1; NR3C1; KAT7; BHLHE40; BRCA1; CTR9; PDLIM1; USP22; ORC2; MYBL2; SREBF1; EZH2; MEN1; MXD4; AFF1; SMARCC1; RNF10; SMARCA5; PHF8; HOXC10; ZNF212; KLF12; SUPT5H; HLTF; TRIM28; KMT2B; BMI1; POLR2A; SAP30; SMAD7; TMF1; TRIP6; MAX; ZNF672; TSC22D4; ELK3; FOXO4; FOXC1; KDM2A; SNW1; POU2F2; SIX2; BATF3; NCOA4; HOXA10; HOXA11; KMT2A; SMARCA4; ZNF532; REST; ZNF384; ZMIZ2; ING1; IRF4; DNAJC1; IRF5; MSC; DYRK1B; SMARCE1; PSIP1; NFKBIB; SMAD2; YAF2; BCLAF1; SALL1; STAT5B; ZNF189; MED6; ZNF16; LPIN2; UIMC1; ADNP; SIX1; PATZ1; RXRB; SETD2; DDX54; SMARCA2; ING2; BAZ1B; TRAK1; SMAD1; KAT5; UBP1; TCERG1; PREB; TRIM32; NFX1; ZBTB14; ASH2L; SIAH2; SFPQ; HMGN3; ASXL1; MYOD1; ELF1; HCFC1; ENO1; NCOA1; PIR; ARNT; PCGF2; VEZF1; NCOR2; PPARGC1A; ELF3; MBD2; ZBTB38; NR2F2; E2F2; PBRM1; ZBTB24; HOXC4; SLC2A4RG; PIAS3; HTATIP2; TAF1D; BAZ2B; RFX5; RNF14; RBBP4; FLNA; SERTAD2; RELB; LIMD1; SMAD4; TADA2A; EYA1; E2F6; SFMBT1; SIM2; ZBTB40; ATF7IP; PHF2; MSX1; BAZ1A; ZNF589; HR; ZBTB1; TFCP2; FOXD1; BLM; IRF2; ZNF146; RARA; EDF1; ZNF410; PRKDC; LMCD1; TRIM16; PTTG1; MEF2A; CBX3; TDRD3; ZEB2; CBFB; MLXIPL; ING3; BASP1; CREBZF; ARRB1; CREG1; HNRNPD; RBL1; ALX1; PMS1; AATF; CREB3L2; ZNF516; STAT1; HMG20A; NFYC; PHOX2A; STAT3; PURA; VGLL4; ARID4A; RBL2; BTAF1; PRPF6; HDAC1; TADA3; SP3; MED1; ETV5; UBE2I; BCL3; ZKSCAN1; MTDH; TBL1XR1; HDAC6; MNAT1; SPEN; PKNOX1; SMAD6; TCF15; NKX3-1; ZNF226; CIZ1; SOX4; NFIB; ZMYND11; CHD7; IRX5; KLF2; CENPF; CITED1; RCOR1; RARB; ZNF248; YWHAB; TFEB; TULP4; TBL1X; RUNX1; FOSL2; JARID2; CNOT1; PIAS2; STAT5A; SUB1; RERE; HMBOX1; MITF; KDM5A; WHSC1; FOSB; SMARCD2; DEAF1; NFATC1; DNMT3B; ELF5; IL16; PLAGL2; HOXB7; MED13; WWTR1; HMGB2; CHD1; NR1H3; TLE4; ZBTB18; SCAND1; MAF; NR1D2; NR4A1; PBX3; TRIM29; DACH1; GATA3; MAFB; IKZF1; TCFL5