Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50706	Naloxone	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	166	ZNF195; ZNF44; NR1H2; TP73; DNMT1; TFAP2A; ZNF586; IFI16; SOX2; GMNN; ZHX2; ZNF688; BACH2; BNC2; ZFPM2; TCF21; ZNF816; TCEA2; ZNF83; ZNF544; HIRA; ZNF264; ZNF611; SOX17; CBFA2T3; TRIB3; SKIL; THRA; E4F1; ZNF665; SALL2; SUPT3H; ZNF180; ST18; KLF13; ZNF43; SSBP2; ARID1A; WNT4; ZNF274; POLR3C; PIAS4; ZNF354A; CDIP1; JUN; ZFHX3; MEIS2; IRF8; SOX13; RAD21; SOX3; ZNF140; ARNT2; RBFOX2; ZNF74; ZNF835; CREM; ZNF654; TGS1; MYCL; ZNF3; NKX2-1; HBP1; HHEX; ISL1; IRF6; ZIC3; BRD7; ZNF141; PRRX1; CUX2; INSM1; ZSCAN18; ZNF232; ZNF551; AR; PRDM10; FOXA1; WT1; TCEA1; ZNF224; TDP2; ZNF93; TOX3; ILF2; SPIB; TCF3; HSF1; MECOM; NFE2L2; ZBTB20; APEX1; ZNF500; BCL11A; ZNF91; AHR; ZBED4; ZNF160; SOX11; TRIM22; AEBP1; ZNF268; EPAS1; RBPJ; OVOL2; PBX3; HIC2; ZEB1; SIX6; FOXE1; ZNF573; EHF; ZNF329; HOXB5; HOXB2; PAX5; ZBED2; LIN28A; ERBB4; PGR; MED24; TFAP2C; TAF7; E2F5; HOXB13; PBX1; ATN1; IRF9; MNDA; NANOG; DDIT3; TOX; POU2AF1; ZNF273; PEG3; ZNF415; ZNF331; ZNF512B; SPDEF; TULP3; FOXF1; GATA6; REL; NR4A3; PBXIP1; TRPS1; ZFP36L1; NFE2L3; LITAF; KDM5D; ZFP36L2; SOX9; TWIST1; HOXB6; MYBL1; NR2F1; KLF7; ZNF423; IRF7; ESR1; BHLHE41; HMGB2; MAF; TBX3; MEIS1; ID3
Down-regulation	173	KDM5B; ELK3; NUP62; ATF1; HOXC6; EDF1; ZFP64; FOXO4; ERBB2; NCOA6; BRD8; TBP; NFIL3; BRD3; RHOA; PSMD9; TOB1; BCLAF1; KLF12; NFKBIB; REST; TBPL1; ARID4B; PRRX2; ATF6; USF2; SMARCA5; YAF2; FOXJ3; BRPF1; CRK; RNF111; ORC2; PDLIM1; MXD4; ING2; BMI1; TP53; FOXC1; NCOA4; STAT3; TSC22D4; BRCA1; NEDD8; TSC22D2; SCAND1; SIM2; RBM39; NFKBIA; HMGN3; JUNB; SMAD3; PHF20; SFPQ; LPIN2; ELK1; BATF3; ARNTL2; CHD1; PREB; XBP1; POLR2A; HDAC1; UBP1; EP400; ING3; SERTAD2; NPAT; SNAI1; RBM14; ZMIZ2; NRBF2; RNF10; PURA; HOXC10; ZBTB11; MED27; AFF1; ZBTB1; POU3F2; MEF2A; NAB1; BCL3; RELB; MSX1; CTR9; SMAD2; NFAT5; PPARGC1A; SMARCA4; RNF14; HNRNPD; HLTF; HDAC7; NCOA1; MTF2; CCNE1; KAT6B; CXXC1; ALX1; HMG20A; SIAH2; ARID4A; BIRC2; KLF2; BBX; COPS2; RBL1; IRF5; ETS2; EZH2; SMAD6; ID2; BHLHE40; LHX6; FOSL2; HOXA1; MNAT1; NELFB; FOSB; JARID2; FOXD1; LMCD1; NFIB; YWHAB; RCOR1; IKZF5; STAT5A; SMARCA2; KDM2A; NFATC1; SAP30; BLM; NR2F2; NR3C2; IRX5; MED6; ZBTB38; PCGF2; TAF10; CTNNB1; RUNX1; ZEB2; PIR; FOS; CEBPB; NCOR2; IRF4; ZNF589; PBRM1; KLF9; MEOX2; TRIP6; MEOX1; ENO1; KLF10; CRY1; AIP; MAGED1; KDM5A; ZBTB18; HTATIP2; EGR3; CREG1; SATB2; TXNIP; NR1D2; SUV39H1; TSC22D1; TRIM29; GATA3; IKZF1; TCFL5