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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID50694 Moxonidine GSE92742 HA1E Human 24h 10uM EID0249
Types Number Response transcription factors
Up-regulation 122 SOX2; NR1H2; ZNF44; DNMT1; NFATC4; PRDM14; ZNF195; TP73; ZNF701; ZNF835; ZNF611; SPIB; GLI2; SNAPC4; ZNF688; CDIP1; ZNF232; ARID5A; ZNF74; AEBP1; RBPJ; AIRE; SALL2; FEZF2; SUPT3H; ZMIZ1; ZNF264; ZIC3; ZNF654; HIPK2; PRDM10; ZNF160; TRIB3; SMARCB1; POLR3C; VPS72; HIRA; RBFOX2; LHX3; ZNF665; IFI16; PIAS4; BNC2; JUN; PRRX1; FOXF2; HBP1; ZHX2; ZNF3; POU5F1B; ZBTB16; SOX15; HLX; MECOM; PPARD; LIN28A; CALR; TCEA1; NEUROD1; ZNF623; ZNF606; RARG; SOX13; CBX4; ZNF573; ARNT2; TCF7L1; ZNF721; NFE2L2; HSF1; TP63; ZNF83; CNOT3; CREB5; ZNF500; ZNF224; USP21; SOX17; ZNF544; CREB3L2; HOXD1; PRDM2; SPDEF; ZSCAN9; CDC5L; OVOL2; FOXA1; TCF7L2; ELF4; CHD8; TULP3; WT1; TDP2; CRYM; AES; ERBB4; ZNF512B; ARID5B; ZFPM2; HOXD11; PAX6; TERF1; KLF7; ATF3; ST18; TRPS1; ID3; NANOG; IRF6; BCL11A; KDM5D; MEIS2; TOX; ZIC1; ZFP36L1; PLAGL1; TRIM29; TOX3; ZBED2; ZNF131; BHLHE41; ID1
Down-regulation 158 KDM5B; ECD; TBPL1; ATF1; FOXO4; ELK3; EGR1; HSF2; RNF10; CCNE1; TBP; FOXC1; ARID4B; NFKBIB; YAF2; ORC2; TMF1; NUP62; ZFP64; SUB1; ZBTB11; BATF3; SIAH2; EP400; BRD3; TBX2; BMI1; NCOA6; EZH2; NPAT; NCOA4; TCERG1; ZNF672; PHF8; GCFC2; RNF14; CTR9; NFYB; RBBP5; NCOA1; AFF1; HLTF; MED6; SETD3; MAGED1; MSC; ZMIZ2; XBP1; UBP1; NR2F2; SP3; BAZ1A; KAT7; SMARCA5; SMAD4; TSC22D2; LPIN2; CHD7; STAT3; BCLAF1; PHF2; PREB; MXI1; ZNF226; HABP4; HOXC6; GABPB1; ZNF516; MSX1; PPARGC1A; LMCD1; FOSL2; LIMD1; SPEN; ZBTB18; IRF4; POLR2A; RFX5; CRY1; ZFX; HMG20A; SIM2; CHD1; ELF1; MXD4; KLF6; KAT6B; IRF5; HTATIP2; TOB1; SFMBT1; NFIB; BAZ1B; CREBZF; IRX5; MED1; ETV5; FLNA; PCGF2; SERTAD2; ZNF589; RBL1; IKZF5; BBX; KLF2; BASP1; SMARCA4; TFDP2; DLX2; SMARCA2; BLM; SIN3B; HIPK3; ZMYND11; TAF10; RYBP; STAT5A; RCOR1; CBX3; VGLL4; PIAS2; CITED1; WWP1; HNRNPD; CTNNB1; TERF2; ETS2; TFCP2; TULP4; RBBP8; TBL1XR1; ID2; YWHAB; SMAD2; PURA; CREG1; EMX2; ZEB2; SOX4; DNMT3B; NR1D2; RERE; ASCL1; DACH1; HHEX; SNAI2; EGR3; JUNB; ZBTB38; SATB2; PIR; HOXB6; TXNIP; TBX3; LEF1; GATA3; SUV39H1; IKZF1
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