Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50611	Dactinomycin	GSE92742	HA1E	Human	24h	10uM	EID0249

Response Information :

Types	Number	Response transcription factors
Up-regulation	197	ZNF586; TFAP2A; ZNF135; ZNF611; ZNF532; CBX7; CUX2; SSBP2; TCF21; MEF2C; SALL2; NHLH2; NR1H2; ZNF180; ZNF665; WDR77; VPS72; MYCL; AES; ZSCAN18; ZNF195; TCEA2; ZNF124; ZNF688; CREBL2; RBFOX2; ZNF264; ZNF350; ZNF44; TDP2; ZNF154; ST18; SPI1; CALCOCO1; ZNF215; SOX17; MED14; ZNF358; IRF6; CALR; GMNN; ZNF160; PRDM10; MYCBP; KAT2B; ZNF551; ZNF224; ISL1; HMGA1; ZFPM2; ZIC3; ZNF816; FOXF2; LIN28A; CARF; SUPT3H; AFF2; EHF; ZNF304; DLX5; HBP1; CTBP1; ZNF140; CNOT3; SOX13; ARNT2; ZNF768; CERS6; ZNF544; SRCAP; IRF8; TRIB3; TWIST1; ZNF667; FOXE1; NEUROD1; ZNF232; ZNF141; ZNF682; EPAS1; SUPT7L; INSM1; ZBED2; ARHGAP35; HIPK2; SNAI2; ZNF423; ZNF606; NR5A2; CDK2; L3MBTL1; TCEA1; TOX3; TP63; SOX18; BARX1; MECOM; SAP18; IRF1; NFE2L3; ZNF587; SOX3; HESX1; HSF1; E2F5; HLX; HOXD3; ARL2BP; TRIM22; ZNF32; RING1; NKX2-2; TCF7; JUP; SLC2A4RG; CDX1; PRRX1; ZNF721; FUBP1; SOX11; FOXF1; ZNF268; BACH2; HIPK3; TBX1; PRDM14; SCAI; ZNF444; KAT2A; ZNF136; HDAC9; FOS; ZNF345; CNBP; ARNTL2; ZNF91; ZNF329; MNDA; HOXB5; NCOA2; TGFB1; BNC2; ZNF500; PPARD; HOXB13; TERF1; REL; ZNF652; HOXD1; RARG; RSF1; MEIS2; OVOL2; ZBTB20; IRF9; RAD21; PEX2; ZNF331; C1QBP; PBX3; HIRA; AEBP1; ZNF589; MED24; PBX1; ZNF711; TOX; ZNF117; TAF9B; ZNF415; PEG3; TTF2; SUPT4H1; CD3D; TRPS1; MYCN; RFX5; LITAF; COPS5; NANOG; ZNF580; ATN1; BCL11A; TGFB1I1; MYRF; KLF5; MYBL1; NFE2L2; ERBB4; ID1; FOXA2; SPDEF; ID4; CITED2; INSR; MEIS1; LEF1
Down-regulation	339	HOXA5; CDK7; NFKBIA; MYC; FOXJ3; HDAC2; CCNA2; NFIL3; FOXO3; USP22; FHL2; KDM5B; TLE1; XBP1; CRK; NRIP1; BRPF1; PUF60; TBP; KLF6; RHOA; FOXC1; ASXL1; BRD8; PHF20; HOXC6; AFF1; ELK3; BHLHE40; ELK1; NCOA4; ING2; NCOA6; TCERG1; RBM14; REST; JUN; TSC22D2; KAT7; MAFF; SNW1; ZFP64; TBL1X; ZNF282; SETD2; EED; ZNF212; ECD; BAZ1A; ZNF410; NR3C1; BRD3; RNF111; SMARCA5; SOX4; CCNE1; EZH2; ING1; TRIP11; CCDC59; TAF9; SETD3; ZNF217; RREB1; JUND; CENPF; KAT6A; TBPL1; KLF10; SFPQ; NEDD8; CTR9; ING3; ZMYM2; ERBB2; CASZ1; KMT2A; NPAT; SMARCD3; MGA; EP400; YAF2; BATF3; ZHX3; FOSL2; NUP62; POLR2A; STAT3; ZNF384; RELA; TOB1; NR2F2; PSPC1; RARA; ZBTB25; ATF1; ELF1; NKRF; FOSL1; ZMIZ1; PPRC1; HOXC10; TRIM28; TSC22D4; ZNF672; ZBTB24; PRPF6; CNOT1; TP53; PATZ1; UBE2I; SP140; MTF2; CHAF1B; NPM1; ZBTB11; ZNF79; DNMT3B; ATF6; BCLAF1; NRF1; E2F6; SIAH2; STAT5B; KAT8; ANKRD1; RAN; HNRNPD; CHD1; KDM2A; VEZF1; FOXJ2; MED27; KLF2; ZBTB40; HOXA7; ADNP2; CEBPZ; SNIP1; CTCF; MNT; BATF; ELF3; NCOR2; TMF1; BLM; NRBF2; PREB; PURA; SAP130; TSC22D3; HCFC2; NFYA; ZNF16; USF2; CRY1; E2F2; HOXA11; RNF4; SMAD1; MED6; SIX1; BANP; SP3; TRIM32; ZNF266; PDLIM1; EDF1; KLF12; TRIM16; PTTG1; TRIM33; MAX; BCOR; SAP30; HSF2; MED13; ASH2L; ARNTL; TAF4; REPIN1; BRCA1; HOXC4; SCAND1; CEBPB; FOXK2; SFMBT1; CHD8; CBFB; HES1; ZMIZ2; HLTF; SMAD2; KAT6B; PMS1; JUNB; MSC; LPIN2; RUNX1; RUVBL2; RBM39; ORC2; DDX54; MLX; ADNP; SNAI1; CREB3L2; RCOR1; ZNF23; GATAD2A; NFKB1; MED1; BAZ1B; BIRC2; ID2; RYBP; TAF1D; DPF2; ERCC3; SIM2; NFRKB; RBL1; YWHAB; ZBTB1; IRF5; MMS19; PPARGC1A; IKZF5; ETV4; PIAS2; ZNF276; OLIG2; SERTAD2; TFAM; PLAGL2; LHX6; HR; IKBKAP; POU2F2; SPEN; HOXA1; TCF12; YBX1; HMGB2; MED7; VGLL4; SOX9; TAF5; FOXG1; TRIM27; HOXA10; ILF2; ZNF263; HSBP1; BCL3; MED23; LYL1; WWTR1; PCGF2; NFIB; HDAC4; USP21; ZNF85; HDAC1; MBD2; BTAF1; CLOCK; RBBP4; KLF4; TGIF1; ZNF629; TCF25; ZNF443; FOXD1; NR3C2; PIAS1; MAGED1; SMARCE1; PRDM4; DLX2; TRIM24; MLXIP; RORA; NFYC; BCL10; MEF2A; SMAD7; RUNX3; NFE2; NFATC1; ZFHX4; SMAD3; PAX8; RXRA; ATF7IP; NCOA1; ELF4; CXXC1; EGR3; YBX3; EMX2; SMARCD2; ARID4A; ZMYND8; COPS2; MEOX1; KDM5D; DEAF1; PITX2; DNAJC2; ATF4; NPAS2; DDX5; TCF7L2; SUV39H1; BRD2; LMCD1; MITF; AIP; TERF2; JARID2; ETS2; PBRM1; ERG; ZBTB16; CITED1; PLAGL1; FOSB; ZFP36L2; MSX1; ZNF131; SATB2; CTBP2; ESR1; KDM5A; TSC22D1; ABL1; TCFL5; GATA3