Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50294	Ditolylguanidine	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	361	ADRB2; SSBP2; ZFPM2; GATA2; ZNF701; WWP1; BRPF1; ZNF227; NFE2; SSX1; ZNF131; CCNT1; ANKRD1; PRDM10; ZNF516; ZFP36L2; NCOA1; ZNF224; GFI1B; TBP; PAX9; BAZ2B; CSDC2; HDAC7; MLLT10; MAK; NR1H2; ZNF440; BRWD1; ZNF44; BNC1; PAWR; GATA1; NR5A2; LMCD1; FHL5; ZBTB6; ZNF623; KAT2B; ZBTB44; CHD2; ZNF292; OVOL1; ZNF200; ZNF696; BACH1; ZNF107; POU1F1; ZNF573; ZNF236; HHEX; FOXL2; ARID3B; ZNF205; TFAP2C; MEF2A; PITX2; ZNF226; CREB3L2; PIAS3; ZNF695; HCFC2; ZNF235; TMF1; ZBTB20; ZNF223; KLF1; ZNF225; NR6A1; TEAD3; ZNF665; ZNF35; ZBED2; GATA6; YAF2; CREBZF; JARID2; ZKSCAN7; OSR2; ASCL2; ERG; DMRT1; ZNF234; ZNF343; HOXD13; PITX1; NCOA3; ZNF117; MSL3; TFCP2L1; ZSCAN31; ZNF493; PRDM5; PIAS1; L3MBTL1; ZNF667; ZFHX2; SIRT7; NLK; AGO2; TRIM24; BPTF; DNAJC1; ZNF362; ZNF41; ZNF551; ZNF358; ZNF682; BLZF1; SOX3; TAF4B; ZNF384; FOXJ1; EVX1; ORC2; TRIM33; SUZ12; CBX7; RFX7; PROP1; ASH1L; NFATC4; POU5F1B; ZKSCAN4; RCOR3; AFF2; POU2F3; MAML3; ZNF254; BARX2; MYF6; HOXC5; SKIL; TRPS1; CUX1; PHF1; NFE2L2; ZNF674; PRDM14; ZNF446; HMBOX1; ZNF711; GLI2; ZNF214; SOX12; FOXN3; PBXIP1; AIRE; ZNF157; TBX19; ZNF764; NKX2-1; POU2AF1; TCF15; ETV3; NFIB; FOXE1; ZNF80; MEF2D; SOX18; TBX4; NHLH1; ZNF180; KDM5B; RBL1; VHL; HDAC6; STAT4; RREB1; ZNF222; TOPORS; FOXD3; ZNF571; ZNF45; HDAC11; ZNF93; ZSCAN9; NR2F1; ZNF646; HNF4G; ZNF160; VEZF1; ZNF721; NEUROD1; TLE1; ZNF770; CIC; PAX4; STAT2; WHSC1L1; KMT2B; NR2E1; ZNF507; THAP9; HOXD11; ZNF471; KLF3; PAX8; ZNF140; MAFG; SMARCA2; NR3C2; UIMC1; VGLL4; TCF7L1; RSF1; MYBL2; CALR; ZNF7; PPRC1; ESR2; E2F8; LHX3; NPAT; ZBTB3; KMT2D; SCAI; ZNF274; ZNF215; MED14; ZBTB39; POLR3F; ELF2; NR2F2; UBE2B; SRF; SNIP1; MYBL1; ZNF135; ZNF83; BRCA2; POU6F1; OLIG2; ZNF787; HIVEP1; E2F5; SREBF1; NR1H4; ZNF536; MYOG; MEOX2; BCL11B; HDAC5; ZNF611; TAF12; SAP130; LIMD1; CREM; NANOG; E4F1; ZMYND8; SMAD4; FOXC1; ZNF675; CHD4; ZNF202; ZSCAN16; ING4; PGR; LYL1; ZNF492; NHLH2; BCL3; USF2; ZNF394; PBX2; PEG3; IRF6; PRMT2; DACH1; TLE4; ZFX; PQBP1; MNDA; EP300; SMAD3; BRF2; LPIN2; TSC22D4; E2F3; DBP; HBP1; ZNF211; DDX17; ZNF544; ZNF423; TBX3; ZNF532; ZNF212; ZNF710; PRDM1; ZNF331; HLF; HSF2; ZHX2; FOXJ3; AFF1; MYT1L; CAMTA2; DAXX; TRIM22; NFATC1; TCF7; GATA4; EN1; ZMIZ1; RBBP5; ZFP69B; PFDN5; NCOR2; YEATS4; ZNF257; ZNF587; KMT2A; TRIM16; ESR1; MAFB; DDX5; MLXIP; MTF2; FOXG1; TRIB3; TBL1XR1; CUX2; BCL6; RERE; MBD4; PPP1R13L; ARID5B; FOSL2; AR; ESRRG; ZNF43; TCF21; PAX5; ERBB4; ZNF512B; SUPT3H; ARID4B; ZNF354A; MAF; SOX17; TCEA1; CARHSP1; ZNF652; ZNF468; NR1D2; EYA2; TTF2; FOXO1; TGFB1I1; ZNF329; RBPMS; BBX; ZEB2; INSR; CREG1; MYB; BHLHE41; LEF1; ZBTB16
Down-regulation	455	HOXA5; ILF2; NR2F6; RUVBL1; HDAC2; CDK2; THAP11; DEK; NFKBIA; EDF1; RFX5; ATF1; CDC5L; NCOA4; SSRP1; ZNF589; CTCF; CCNH; AIP; ATF6; NUP62; HIF1A; RB1; GTF2A2; CENPF; WIZ; SNW1; TAF9; UBE2L3; DEAF1; CARM1; BRD8; FOXM1; TFDP1; ETS1; TAF10; SERTAD2; ZNF580; PRPF6; CTR9; MAX; NELFB; USP22; DRAP1; TCEA2; ZFP64; SMARCC2; THAP4; C1QBP; CREB3; TSG101; BCLAF1; GTF2IRD1; MGA; NOC2L; PATZ1; ABL1; TGFB1; SMARCD2; BRD4; ECD; ITGB3BP; RFXANK; NFKBIB; ZBTB1; HOXB2; GTF3A; SP100; ZFP36L1; HSBP1; CBX3; MYC; IKBKAP; HOXB6; CIZ1; RNF4; TCF12; HOXA10; KDM5A; SF1; TRIP6; SMARCA4; SREBF2; ERCC3; DNMT1; FOXO3; RAD21; BRD7; SNAI2; SP2; NFYC; ZNF410; RNF6; DPF2; RELB; COPS2; C1D; REPIN1; CCNA2; PSMD9; CBFB; KAT8; NCOR1; RBM14; SUV39H1; YEATS2; USP21; ERCC2; KDM2A; SOX4; ZNF672; ZBTB17; TUB; TAF6; ZNF217; BAZ1B; PTTG1; ZNF148; HOXB5; EED; CEBPD; SMAD6; PDLIM1; SAP18; TRIM28; TCERG1; JUN; RFC1; SMAD2; CCNE1; GMNN; SMARCD1; PMS1; ZFHX3; ZBED1; SMARCA1; MED27; ZBTB48; SP3; ZNF528; USP16; REXO4; SIM2; RELA; NAB1; PRRX2; CCNC; KAT6A; ARID4A; NPM1; ZNF232; ZNF281; HMGA2; TAF7; HMGXB4; VPS72; KLF6; MEIS1; CCDC59; HOXA11; MAML1; YWHAB; THAP7; TBPL1; TFAM; BRCA1; APEX1; SETD3; XRCC6; TCF25; FOSL1; FOXP3; BIRC2; NFIL3; RAN; HNRNPD; XBP1; SUB1; ELF1; HAND1; TULP3; BRD3; KAT5; SMARCA5; TWIST1; ALX1; GCFC2; THAP3; CBFA2T2; MED20; PMF1; HOXA7; HOXD10; WWC1; DNAJC2; ADNP2; PARP1; ZBTB38; MED12; NSD1; HEY1; EHMT2; PUF60; ATF2; PCGF1; SMARCC1; ZNF195; MNAT1; HOXD9; PLAGL2; PSMC3; HOXB1; NFKB1; MLX; PHOX2A; IRF9; CEBPG; CENPB; GTF2A1; TOX4; ZNF282; NKRF; PNRC1; FUBP1; ACTL6B; CRY1; MNT; THRAP3; ATF6B; DLX6; ARNT; BATF3; AES; MED13; IFI16; ID2; SAFB2; ARNT2; TP53; ENO1; ID3; MTF1; BTAF1; ZBTB11; HMGN3; PIR; MED21; HDAC3; FOS; MDFI; RORC; HOXB7; SALL2; ADNP; MXD3; MED1; TBL1X; STAT6; GTF2F1; BTG1; RUVBL2; NONO; ISL1; SHOX2; MYNN; MED16; TGIF2; BTF3; EMX2; EZH2; CBX6; MEF2C; RBBP8; SFPQ; ID1; SMARCD3; TERF2; ZNF562; FOXD1; ZNF146; MBD1; HLTF; MED7; SATB2; KAT2A; SIN3B; YY1; CRYM; HOXA4; ZNF408; URI1; BATF; HDAC1; MECOM; FOSB; ZNF248; PCGF2; ZNF552; TLE2; CHAF1B; ZNF576; HNF1B; CSDE1; GBX2; DR1; MTDH; RBL2; DMTF1; RYBP; ZNF189; ZNF668; ARNTL2; ZHX3; RNF138; HMGB2; TCFL5; HOXB3; ZNF593; RBFOX2; PHF20; NAB2; EGR2; ZNF783; GLI3; CNOT3; CNOT6; MXI1; CAMTA1; CDK8; NFIC; HOXC6; ACTL6A; TOB1; FLI1; PRDM12; MDM2; NCOA6; HIRA; ZMIZ2; ZFHX4; SFMBT1; MKL1; NFKB2; CHD3; EGR1; TRRAP; LZTS1; TGS1; ZNF444; ZNF12; NR0B2; RUNX1; STAT1; SMAD1; ELF4; BARX1; SETDB1; HOXB13; ING3; CNOT1; SP110; ATF3; PURA; KLF4; THRA; CHD1; SMARCB1; BHLHE40; FOXN2; ZZZ3; MEN1; BMI1; ZNF32; RBM39; ZNF22; PLAGL1; RBPJ; HIPK2; PBX3; TXNIP; ERF; JUNB; COPS5; BASP1; MSX1; TDP2; TSC22D3; PTRF; SIX1; FOXF1; ZNF266; PEX2; KDM5D; DLX2; PBX1; RXRA; SIM1; ZBTB18; E2F2; ARRB1; BAZ1A; NR4A3; FOXF2; JUND; CHD9; EGR3; POLR2A; ZIC1; CREB5; CHD8; TAF11; ETV4; RNF141; IRF7; SAP30; HMGB1; CITED1; CTNNB1; TGIF1; GTF2I; ZKSCAN1; DLX5; MED6; CTBP1; ZNF419; KLF7; MAFF; ETV5; CITED2; CREBL2; KLF11; HOXD3; VDR; PSMC3IP; CBX4; KLF10; MEOX1; SOX10; HMGA1; MYRF; SOX9; TOX3; CREB1; NKX3-1; HIPK3; ST18; BCL11A; IRF8; GATA3; TFAP2A; ZNF586; TBX2; ETS2; NR3C1; SOX2