Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50293	Doconexent	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	333	ADRB2; ZFPM2; SKI; ZNF701; SSBP2; KDM5A; SSX1; ZNF331; GATA2; SMARCA1; ZNF614; KLF3; RARA; WWP1; HIC2; IKZF2; SKIL; FOXE1; ZNF394; ZNF205; CEBPD; ASH2L; HLX; CHD2; NANOG; ZIM2; TFCP2L1; ZBTB24; LMCD1; LIMD1; ZNF132; BCL11B; ZNF695; NFATC1; ZNF273; ZNF432; POU1F1; POU4F2; CREM; NR1H2; BNC1; ZNF227; ZNF835; MAK; ZNF226; KLF4; ZNF528; SMAD5; CAPN15; ZNF696; PEG3; ZNF157; SND1; ZNF135; HR; ZNF225; EMX2; PROP1; ZKSCAN7; POU2F3; NR1H4; ZNF391; ZNF223; ZNF492; STAT2; BACH1; CSDC2; FOXJ1; NFE2; TFAP2B; NCOA1; ZNF35; PITX2; PIAS1; NFAT5; SP1; NRBF2; PIR; PRDM1; BARX2; NCOA3; ZNF85; ZNF180; PAX4; SIX5; TAF12; WHSC1L1; ZNF770; SAP130; PRDM14; KMT2D; OVOL1; AFF1; CREB3L2; KLF8; TRIM22; ZNF665; SIX3; PRDM5; KAT7; CHAF1B; ZNF480; ZNF222; HMX1; ZBTB20; PPARA; HNF4G; TFAP2C; PITX1; ZNF236; SOX18; THAP10; ZNF234; GFI1B; ZNF623; HOXC5; ZNF813; GATA6; NFYA; ZNF350; NKX2-2; ZNF224; ZFY; ZNF571; ZBTB3; ARID3B; TSC22D1; NEUROD1; POU5F1B; ZNF764; FOSL2; IRF5; NR3C2; BRWD1; ZNF550; TBP; ZNF214; SOX3; LHX3; TMF1; ZNF682; OSR2; ZNF667; E4F1; TRIM25; MYBL2; MAF; HDAC11; NR5A2; RORA; MAGED1; TEAD1; ETV3; ZNF334; TBR1; ZNF440; ZNF286A; ZNF292; ZNF74; ZFP36L2; RBL1; ZBTB39; DYRK1B; TCF7L1; PIAS2; MYF6; NR0B1; LIN28A; MYT1L; USF2; MSC; ZBTB6; BCLAF1; GATA1; TCF7; ZNF329; HOXA2; PAX9; MAFF; KAT6A; ANKRD1; ZNF281; TULP2; ZNF721; EGR3; TBX19; FOXL2; BCOR; WDHD1; MED31; ZNF34; MED15; DMRT1; ZNF460; RSF1; BRIP1; ZNF93; ZNF239; HIVEP2; ZNF507; ZNF160; MLXIP; PML; ZNF430; NR4A1; POU3F1; ZNF780B; ZNF674; FHL5; CBFA2T3; TULP4; EVX1; VGLL1; PNRC1; MNDA; TRIM33; POU6F1; EYA3; TFE3; TFDP2; FOXN2; MAFB; ZNF816; ZEB2; SRF; NPAS2; ZNF551; BNC2; PBXIP1; SUV39H2; HDAC7; ZNF692; EGR2; GLI2; CNOT2; LZTS1; GFI1; TRIM24; ZKSCAN8; ZNF587; ZNF264; TBX1; ZXDC; MYC; RBPMS; CIC; SMARCD3; ZBTB44; KMT2B; PRKDC; ZNF112; PRDM12; ZNF155; RBM14; ZNF557; EBF2; AFF4; RARG; EGR4; ECD; PLAGL1; EPAS1; ZNF117; ZNF552; SIM1; ZNF669; DNMT3B; HESX1; UBE2B; FOXJ2; ASH1L; L3MBTL1; ZNF257; SOX17; NFE2L2; PAWR; EP300; NFE2L3; SMARCA2; AEBP1; ZNF611; ZNF44; ZNF787; SAP30; CDX1; TRPS1; PGR; MITF; CREB3L1; MAFK; GTF2I; TERF1; KLF9; INSR; SCMH1; MAFG; CUX2; BHLHE41; ZBTB16; AHR; NR4A3; CARHSP1; ZNF33B; TRIM28; TCF21; KAT6B; WT1; NR2F1; HSF2; JARID2; TXNIP; ZNF304; YBX2; ZHX2; ETS2; NKX2-1; SMAD3; KDM5D; ARNTL; ZSCAN18; ZNF415; EN1; CTNNB1; CD3D; MYBL1; BTG1; HLF; ZNF134; NR1D2; AR; HMGB3; FOXO1; ELF5
Down-regulation	466	SCAND1; NRIP1; HOXA5; NR2F6; ATF1; ILF2; RNF4; EDF1; RFX5; LOXL2; CDK2; ATF6; HDAC2; PSMD9; RUVBL1; DEK; ZNF589; ITGB3BP; NFKBIA; MAZ; RB1; ATF5; CDC5L; GMNN; NUP62; ZNF593; GTF2A2; AES; CCNH; SERTAD2; TSG101; TAF10; WIZ; MGA; C1QBP; PCGF1; RBM39; CDYL; PATZ1; NKRF; NELFB; DNMT1; PCGF3; SIN3B; RFXANK; AIP; PRPF6; COPS5; GTF2IRD1; ID3; TAF9; PMF1; SUB1; DEAF1; SMARCA4; RFC1; ATF2; ZNF232; IKBKAP; DR1; CHD7; DRAP1; REXO4; TADA3; ZNF24; FUBP1; CARM1; RBBP8; HOXA10; MEIS1; USP21; TLE4; MED21; CENPB; APEX1; TRIP6; GTF3A; RAD21; ZNF576; PHF1; MXI1; ERCC3; ABT1; ZNF146; ZBTB1; FOXO3; SSRP1; CBFB; HOXB5; HOXB6; HOXA7; DNAJC2; SRCAP; NFYB; IRF3; HOXA4; ACTL6A; PSMC3; NCOA6; HMG20B; MYCBP; EED; MED27; TDP2; ZBTB17; TRIP4; SUPT4H1; CENPF; PTTG1; TOX4; BATF3; TBX10; PMS1; CIZ1; ARID1A; NFRKB; VPS72; CTR9; SATB2; FOXJ3; RNF138; ZBTB11; DLX2; CBX3; ZBTB7A; KDM5B; SMARCD1; BTF3; CTBP1; ZNF131; CREB3; PDLIM1; BTAF1; ID1; TRIB3; BIRC2; RNF6; MED16; COPS2; CCNE1; RNF10; CHD8; NFKB1; WDR77; WWC1; TUB; JUN; RAN; ELK3; ZNF140; ATN1; ZZZ3; PRDM4; SP140L; THAP3; BRD4; SAP18; HLTF; ASXL1; CCDC59; SUV39H1; STAT6; ELF1; ZMYND8; ZFP64; ZNF562; PEX2; KAT8; MED1; MNAT1; PHF2; THAP4; ZNF143; GATAD2A; XRCC6; MTDH; CHD1; HMGXB4; TCF4; ZFHX3; SPDEF; MTF2; PIAS4; ZBTB38; FOXF1; SPEN; DPF2; ZMIZ1; KMT5A; ATF4; CNBP; SF1; ZNF580; ZNF668; ARNT2; SREBF2; C1D; BAZ1B; MED4; UBTF; PBX1; HOXB2; NPAS1; TAF11; CRY1; ERBB2; TCF3; SMAD4; NAB1; ID2; MED17; UBE2L3; SMAD7; VEZF1; NR2C1; HOXD10; ARID4A; ARID5B; MDFI; ZNF324; ZNF148; CSDE1; MSX1; SETDB1; HDGF; HINFP; ZNF426; THRAP3; PBX3; HOXB3; DLX6; PAXBP1; UBP1; SMARCC2; NR2F2; SETD3; TRIM27; ARNTL2; MAPK8IP1; MAML1; TP53; ATF3; CALR; SMAD1; KDM2A; ZNF266; ZBTB18; RBFOX2; MZF1; URI1; DACH1; NFIL3; MED20; HAND1; HOXB7; PRRX2; SFPQ; HDAC3; KLF5; RING1; ETV5; ZNF12; EZH2; EHMT2; MXD3; BCL10; MYNN; ZNF652; FOXM1; HOXD9; RBBP7; ZHX3; SNW1; MEIS2; MLX; KAT2B; IRF9; ACTL6B; GLI3; SP3; BRD3; PITX3; FLNA; ZNF263; MTF1; WHSC1; E2F5; RNF111; CERS6; SP2; PSMC3IP; FOXO4; ETV1; MECP2; HABP4; ZNF22; TAF1D; TRIM29; RXRB; ERF; FOXF2; ZBED1; SHOX2; KAT5; ZNF512B; NFATC4; USP16; ETV4; CREB5; GBX2; PHF20; SOX12; ZNF7; CDX2; ARID4B; TCF12; UIMC1; HES1; NR1H3; SMAD6; ZNF410; HMGB1; ZBTB40; EWSR1; ZMYM2; ZNF189; TBL1X; SIX1; TAF1A; SUPT6H; TRIM16; DMTF1; ZNF217; FOXN3; BCL11A; MEOX1; FLI1; SALL1; MED13; TULP3; MBD1; HNRNPD; IRF8; ZNF45; DAXX; LITAF; TTF1; POU2F1; ZNF84; SUPT3H; TERF2; SNIP1; TFAM; YBX1; PTRF; BRD2; TGIF2; PSPC1; ZNF536; HDAC4; OVOL2; BARX1; ZNF177; SP140; ZNF133; TLE2; TFCP2; SUMO1; E2F6; TOB1; MTA1; SOX9; BMI1; PLAGL2; RELA; ING3; BCL6; ZNF184; SIRT7; FOS; CHD9; CREG1; LHX1; NHLH2; BCL3; MED23; JUND; ENO1; VGLL4; TBL1XR1; ZIC1; SIX2; PA2G4; PHOX2A; TCEA1; SP110; RUNX1; ZNF195; TCF7L2; TTF2; STAT1; SIAH2; CCNC; PREB; DLX5; PSIP1; JUNB; CHD3; ZFHX4; ARID5A; IRF7; MED6; SP100; SMARCB1; SNAI2; MTA2; TP63; WWTR1; RXRA; RCOR1; IRF2; CERS4; ZMIZ2; ADNP; ELF2; CLOCK; FOXD1; SAFB2; JAK2; HMGB2; HEY1; GTF2F1; CBX4; KMT2A; E2F3; BAZ1A; TWIST1; HMBOX1; CITED1; YBX3; SIM2; MBD4; KLF6; INSM1; ZEB1; TFAP2A; NFIB; TOX3; MECOM; E2F8; CREB1; TEAD4; ASCL1; PPARGC1A; IRX5; VDR; KLF7; BASP1; FOXA2; HOXC10; ST18; HMGA1; MYRF; STAT3; SOX2; NR3C1