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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID50271 Brimonidine GSE92742 HA1E Human 6h 10uM EID0247
Types Number Response transcription factors
Up-regulation 338 ADRB2; PPARG; ZNF701; SSBP2; CREM; NFX1; KDM5A; ZFY; WWP1; MXD1; MEF2C; GATA2; SKI; ZNF528; BRWD1; VGLL1; ZNF331; TMF1; ZBTB20; ZNF135; ZBTB24; EGR2; LPIN2; CARF; KLF4; IRF5; SOX13; ZNF835; BARX2; TFCP2L1; FOXL2; KLF3; NR2F1; SAP130; ZNF764; ZNF85; MAF; NFATC1; ZNF573; SP1; PEG3; NR1H4; NRBF2; STAT5A; ZFPM2; ZIM2; NEUROD1; TCF21; CHD2; NSD1; HOXC5; ZNF226; REST; NR1I2; ZNF236; AFF4; ZNF492; ZEB2; NR1I3; GBX1; ZNF225; MAK; IRF6; ZBTB3; WHSC1L1; MED31; ZNF552; TXNIP; PITX1; LIMD1; TBX1; HR; PIR; NR5A2; BNC2; NFYA; SOX18; ZNF813; ZBTB7C; ZNF623; SP4; SKIL; SMARCA1; PLAGL1; PRDM5; TRIP11; ZNF253; ZNF132; ZNF571; CIITA; MLLT1; ZNF432; PHIP; EGR4; MYF6; PML; ZNF696; FOXJ1; BCOR; ZNF287; IKZF2; ZNF721; ELF3; ZNF665; KLF11; KLF10; CDX1; LZTS1; AHR; HIVEP2; MAFF; RARA; NPAT; WNT4; CREBL2; AGO2; TBR1; CD3D; ZNF157; ZNF507; GABPA; MYCL; ZNF329; SSX7; EHF; EMX2; HMGB3; ZNF442; BHLHE41; LYL1; TFDP2; SOX5; ARNT; IL16; TAF7L; OVOL1; ZNF816; BCL11B; SCRT1; ZNF286A; PGR; RSF1; ZNF180; TRPS1; ERG; SOX21; ZNF44; ZNF343; SRY; NFIX; TLX3; CTNNB1; MED7; ZNF160; AEBP1; TBX4; ZKSCAN4; SMARCA5; SMARCA2; ZNF282; TCF7; TAF5; IKZF3; STAT2; ASCL3; PRDM2; ZNF629; ZNF239; EPAS1; ZFP37; RFX7; NFAT5; JAK2; ZKSCAN8; PAX8; ZNF33B; TFEC; ZKSCAN7; ZNF688; ZNF214; GRHL2; CBX7; PKNOX2; FOXN2; ZNF695; THRB; HLX; KMT2D; RNF141; EVX1; TEAD1; ZNF510; TFE3; ZNF606; KDM5D; PLAG1; NR4A1; KLF12; ELK4; OLIG2; FOXJ2; EBF2; NCOR1; HOXC4; ATF7; ATF7IP; ASH1L; MECOM; HSBP1; YBX3; NEUROD2; CTBP2; GCFC2; PIAS3; ZBTB7B; ING2; ZNF35; NR3C2; SMAD2; MYEF2; HDAC6; NCOA3; TFAP2B; POU2F3; RELB; BPTF; TOPORS; POLR2A; ZNF529; HDAC11; STAT4; ZNF493; FOSL2; WT1; HOXC10; BAZ2B; ZBTB39; ZNF136; NKX2-2; BACH2; HOXC6; ZFX; ZEB1; ZNF254; SUV39H2; ETV6; IFNB1; MYT1L; UBE2B; OSR2; BLM; EP400; PKNOX1; RUNX3; FHL5; ADNP; NLK; BLZF1; TBX2; SOX3; FOXE1; PPARD; PLAGL2; ZNF350; PPARA; SETD2; ZNF443; CBFA2T3; RORA; RBM14; ZNF611; MAFB; SOX17; TRIM33; NANOG; NRF1; SMARCA4; ZNF423; MLXIP; ZNF544; DNMT3B; HIPK3; BRCA1; ZNF93; ZNF75D; ZNF257; NCOA1; MSC; MITF; AATF; TWIST1; ZNF14; GFI1; REL; HLF; BHLHE40; LHX6; GATA3; ZNF587; FOXO3; CUX2; BATF; HOXD3; IRF2; TBX21; TRRAP; ZMYND11; ZSCAN16; LIN28A; YBX2; BACH1; ZSCAN18; SAP30; PRRX1; HIPK2; NR1H3; KAT6B; ZBTB16; NR4A2; HTATIP2; HEY2; IRF4; ZNF468; HMGB2; TSC22D3; CREB3L1; MEOX2; ERBB4; FOXG1; ELF5; EGR3; FOXD1; KLF9; TOX; MYCN; BASP1; ESR1; PSIP1
Down-regulation 464 HMG20B; SCAND1; NRIP1; DRAP1; ABL1; HOXA5; LOXL2; NR2F6; ATF4; PSMD9; ZNF589; CCNH; ITGB3BP; GTF2A2; NFKBIA; MAZ; AES; PCGF1; ZNF580; TAF6; ILF2; RHOA; ZNF593; NKRF; RNF4; ENY2; ATF5; RFX5; GMNN; PMF1; RBM39; DNMT1; SUB1; CERS6; THAP11; SF1; GTF2IRD1; SRF; GTF3A; EDF1; APEX1; ZNF76; TAF9; RFXANK; DEAF1; IKBKAP; SIN3B; THAP4; MED27; SUPT4H1; COPS5; NELFB; ZNF146; ARID1A; TSG101; ZNF24; HDAC3; USP16; VPS72; FUBP1; PATZ1; ABT1; ZBTB17; AIP; FOXJ3; BTAF1; ZNF410; RNF138; WIZ; C1QBP; RAN; PCGF3; RNF10; CDYL; ZZZ3; ZNF444; THAP7; SMAD7; ZNF131; VEZF1; TLE1; PHF1; HMGXB4; HOXA10; TDP2; CNOT3; SP110; USP21; MGA; ZFHX4; ETV1; BCLAF1; ID3; TBPL1; ZNF140; NOC2L; COPS2; ACTL6A; PBX1; HOXA7; MED13; MTF2; TRIM32; BIRC2; XRCC6; HOXA4; SRCAP; CCNC; IRF7; ZFHX3; IRF3; NFRKB; MYC; WDR77; LMCD1; ZNF576; DLX2; FLNA; ATF2; CSDE1; TEAD3; CHD1; MED20; CREB3L2; NCOA4; HMGXB3; RBFOX2; PEX2; RNF6; TRIP6; SREBF2; TBL1XR1; SUPT6H; SMARCC2; CARM1; DAXX; ZBTB18; PDLIM1; PIAS4; BRD4; DNAJC2; RFC1; NR2C1; SMARCD1; HNRNPD; MTDH; SIRT7; ZBTB7A; TGFB1; ZNF668; ZNF232; ETV4; JUND; CHD7; PRRX2; MEIS2; GMEB1; ZNF446; ZMYM2; ZNF263; JUNB; CHD8; SMARCB1; CALR; CNBP; HOXD10; TCEA1; CCNE1; ARID5B; SMAD1; ZNF281; EHMT2; PMS1; WDHD1; CCDC59; CITED2; ERCC3; ZNF266; HAND1; ZBTB1; MLX; UBE2I; RBBP8; MED24; NFYB; DR1; KMT5A; MSX1; SATB2; ZMYND8; ARID5A; HSF1; WWC1; DLX6; MNAT1; HABP4; TAF10; BRD7; HOXB3; HOXB1; TRIP4; ELF1; CENPB; TOX4; MED15; GBX2; TRIB3; HIRA; SCMH1; PTTG1; ISL1; ERF; CDC5L; BCL3; ZBTB40; SPEN; MBD3; URI1; CBFB; ZMIZ1; FOXN3; MDFI; SOX9; ARL2BP; PIAS1; IRF9; FOXP3; ZNF84; RFXAP; UBP1; CBX3; ETV5; ZBTB11; PTRF; SUMO1; VGLL4; SMAD3; NHLH2; ZNF174; CRY1; PBX3; BTF3; ZNF250; RYBP; PREB; CEBPZ; FOXF1; ZNF536; HDAC1; ZNF692; ID1; GTF2F1; MZF1; CBFA2T2; SP140L; TAF5L; TADA3; PAXBP1; CEBPB; GLI3; CREB5; PRDM10; LDB1; TFAM; CBX4; SNW1; HLTF; GMEB2; ZNF672; PSMC3; ZNF426; CTBP1; RXRB; HMBOX1; ZNF12; BAZ1B; KDM5C; NCOA6; CIZ1; DEK; CDIP1; MXI1; TRIM27; ARID4B; ATN1; PHF8; TAF11; TBX6; NR1H2; BRCA2; RING1; CEBPE; ZBTB38; TBL1X; ING3; CITED1; ZNF324; ID2; SMAD6; SUPT5H; CDK8; ZNF768; ARNTL; ZNF562; EWSR1; NEDD8; BRD2; ZSCAN9; YEATS2; POU2AF1; TULP3; TOX3; NPAS2; SMARCD3; JARID2; E2F4; TAF9B; NFKB1; E2F5; NCOR2; HOXB9; ATF3; KLF7; HIPK1; ZKSCAN5; SP100; BRD3; SERTAD2; TERF2; ZNF512B; PQBP1; HHEX; ZNF217; SIX1; POU2F1; KAT8; DLX5; ZFP64; PSMC3IP; ZSCAN5A; MYRF; UBE2L3; THRAP3; SAP18; CEBPG; ZNF195; SUPT3H; BANP; UIMC1; ZSCAN2; NPM1; KLF1; TGIF1; ACTL6B; HOXD11; WHSC1; PSPC1; ZNF16; MAML1; KAT2A; NFKB2; KDM4C; CERS4; DMTF1; ELF4; TLE2; ZNF7; FOS; E4F1; TSC22D2; ZNF384; TCF25; HDAC4; MEIS1; NKX3-2; NAB1; CIC; TCF3; CXXC1; NONO; E2F6; TAF1A; ATF6B; TCF7L2; SP140; MTA1; STAT1; HOXB2; E2F8; ZNF219; ZNF133; KMT2B; REPIN1; RNF14; HOXB6; JUP; PRDM4; RELA; SOX12; TAF7; SAFB2; HMGA1; CREG1; HDAC9; SALL1; E2F3; KLF13; BMI1; POU3F2; ZNF467; MMS19; CASZ1; MED1; ARNTL2; ZHX2; ADNP2; STAT6; SREBF1; TGFB1I1; POLR3F; MED4; CEBPA; TFEB; WWTR1; FOXF2; MECP2; VDR; YEATS4; E2F2; HOXA1; SOHLH2; ZNF184; ZNF652; RBBP7; TCF20; PAWR; TAF1D; FOSB; ZNF419; CHD9; RBBP4; SIX2; ZNF177; BATF3; CREB1; TRIM24; YWHAB; CALCOCO1; CNOT6; DACH1; MEOX1; ELK3; HMGB1; RCOR3; SNAI2; STAT3; BCL6; TBX3; ID4; TRIM29; EYA1; ASCL1; INSM1; SOX2
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