Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50252	Saclofen	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	363	ADRB2; NEUROD1; ZNF331; KDM5A; KLF3; ZFY; ZNF701; PLAG1; CREM; GATA2; SKI; BRWD1; ZFPM2; EGR2; ZNF835; KLF4; RARA; EGR3; ZNF135; CEBPD; BACH1; OVOL1; ZNF629; ZIM2; NFX1; UBTF; EMX2; IKZF2; SOX18; NFAT5; BNC1; SUPT7L; TXNIP; NR1H2; TFCP2L1; ZNF165; LPIN2; ZNF10; PEG3; KLF12; ELF3; CHD2; SOX5; NAB2; PRDM1; OVOL2; ZNF334; ZBTB24; RFX7; CARF; CTCF; MYT1L; BCL11B; ASH1L; NKX2-2; AEBP1; ATF7IP; TFE3; NR1I3; ZNF253; ZNF507; ESR1; TGFB1; HOXD3; ZNF695; TAF7L; FOXE1; MXD1; MAF; THRB; ZNF391; NR1H4; SSX1; STAT5A; SMARCA5; IL16; ZNF180; SND1; ZBTB3; ZNF214; FOXI1; CUX2; MLXIPL; NCOR1; ZNF571; RNF141; SMARCA1; BHLHE41; FOXL2; ZNF510; PITX1; NFIL3; ZNF682; SP4; SMAD7; NRBF2; WT1; ZKSCAN8; SP1; NR5A2; FOSL2; AFF4; RSF1; CIITA; NFATC1; ZNF141; BNC2; WHSC1L1; MDM2; TRIM28; ZNF132; ZNF711; TULP2; OSR2; NR3C2; ZMYND8; CSDC2; ZBTB39; HR; SHOX; ZNF225; STAT2; MNT; ZNF154; DDX17; SALL2; ZBTB25; PRDM5; SSBP3; SKIL; KLF11; ZNF813; MAX; TFDP2; GRHL2; MECOM; ZNF667; ZNF671; CCNT1; POU6F1; SRY; RREB1; ZNF493; TFAP4; PRDM2; PLAGL2; HDAC6; TOPORS; ZNF394; ZNF212; EGR4; ZBED2; EP400; PGR; HNF4G; ZNF236; TAL1; SOX21; NANOG; SOX17; NR4A2; PKNOX2; HOXD11; KDM5D; ZBTB20; RELB; ZNF492; SAP130; TRIM33; ZNF528; ERCC2; CDX1; ZNF440; CDIP1; ZNF665; ZNF721; PAX7; KAT6A; GCM1; ZNF623; PAX4; RAX; CBFA2T3; SMARCA2; OLIG2; HEY2; PPP1R13L; ZNF208; NSD1; SP2; GTF2I; ZNF14; IKZF3; ZNF273; SAFB; NR4A3; HOXC5; ZNF286A; PPRC1; LZTS1; E2F5; WWP1; L3MBTL1; TAF4B; TCF21; NR4A1; UTF1; ZNF780B; HMGB2; NCOA2; ZNF217; CBX7; LDB1; PBXIP1; CREBL2; MXD4; ZNF506; MLXIP; PAX8; GATA1; ECD; RORA; ZNF85; NR1I2; JARID2; ZBTB44; TEAD1; POU3F1; GLI2; PPARA; PML; ZNF274; TCF7; HES1; HMG20A; ZNF205; YBX2; ARRB1; PURA; KAT7; AFF2; ZNF22; ZNF764; VENTX; DNAJC2; IFNB1; DDX54; HDAC7; ZNF415; ZNF117; YAP1; TBX2; HIVEP2; EHMT1; ZNF160; E4F1; TDRD3; NFYC; GFI1B; ZNF254; HESX1; ZSCAN18; ZFP36L1; RUNX3; KDM5B; PBX2; MYCL; NR2F1; ZNF574; MEF2C; HIC2; SCAI; RBBP7; TRIM22; MYCN; ZNF529; LIMD1; NFE2L2; EHF; NKX2-1; KLF10; LEF1; SMAD6; MDM4; CARHSP1; MAFG; HLF; RBPJ; MED12; EZH1; TGS1; SOX4; CD3D; IRF8; TAF5; CHD3; ING2; HOXD1; AHR; CAMTA2; KMT2A; IFI16; KAT8; IRF4; MEN1; ZNF257; REL; VDR; PRKDC; MAFB; ZNF136; TRIM25; PRMT2; CTNNB1; BHLHE40; PAWR; SREBF1; MKL1; RCOR1; PHOX2B; GATA3; SAP30; ZNF175; CTR9; RBBP5; ZNF43; JUNB; ZNF443; MAGED1; LHX6; IRF6; ARID5B; RERE; SFPQ; PREB; ETS2; NPAT; NFE2L3; PHF20; ZNF124; BCL6; MED14; TRRAP; TERF1; HOXB7; KLF9; LIN28A; FOXO1; HIPK2; ZNF329; BCOR; TSC22D3; DDIT3; YWHAB; SMARCD3; ZNF532; HOXB6; RBPMS; EPAS1; BBX; ID4; PSIP1; CRK
Down-regulation	421	HMG20B; SCAND1; LOXL2; ATF1; NRIP1; DRAP1; ABL1; HOXA5; ILF2; TLE1; RUVBL1; RHOA; RFX5; ITGB3BP; NKRF; GMNN; MAZ; DEK; ZNF410; ATF5; HDAC3; EDF1; ATF4; IKBKAP; RNF6; SUPT4H1; ZNF266; RBM39; PCGF1; ZNF146; ZNF580; BCLAF1; HOXA4; SUB1; C1QBP; RNF138; CDYL; PEX2; TAF7; PTTG1; VGLL4; ZNF593; WWTR1; NOC2L; ZNF45; ZNF131; HOXA10; CRY1; ZNF24; APBB1; NELFB; CENPB; MED27; FOXJ3; TOB1; TAF6; VPS72; XRCC6; TRIP4; AES; MED17; SF1; ZNF76; BRD8; VSX1; ZNF263; FOXO3; MYC; DLX2; HOXA7; RXRB; GBX2; PIAS4; ZNF232; SLC2A4RG; ZNF35; FUBP1; ZNF140; PMF1; TULP3; PMS1; ZZZ3; TBL1XR1; CBX3; HOXA6; TBX10; USP16; PHF1; PRRX2; RUVBL2; ATN1; ELK3; FLNA; CENPF; KDM2A; SATB2; PSMC3IP; BIRC2; ZNF446; GTF3A; SIRT7; CRX; MLLT10; KMT5A; MTF2; TSG101; SHOX2; LITAF; SMARCD1; NFRKB; CHD7; ARID1A; RBFOX2; USP21; TRIB3; ZMYM2; TBX3; TDP2; VEZF1; ZMIZ1; ZNF652; BCL3; DAXX; HMGXB3; MED13; CREB3L2; BMI1; ZNF7; UIMC1; DEAF1; ZFHX4; SPEN; MLX; EN1; REPIN1; PTRF; YEATS4; ZBTB1; ERBB2; ZNF211; PDLIM1; NKX2-8; JUND; HDAC4; ZBTB11; REXO4; HIF3A; TAF11; SMAD3; ZNF148; RFXANK; RAN; PBX3; CEBPZ; ZKSCAN5; BRD4; SNW1; HTATIP2; BRD2; SIX1; ZSCAN32; NPAS1; MXD3; ZNF276; WWC1; CHAF1B; ID2; ZNF155; SSRP1; ZFP64; NR2C1; MYF6; SRCAP; BRD3; BATF3; ZNF12; BRCA2; LZTR1; SP3; ZSCAN5A; THAP4; MNAT1; RYBP; ZNF302; SCMH1; THAP3; ING3; ZBTB7A; ERCC3; SUPT3H; CXXC1; ZNF224; CCDC59; ZNF16; ACTL6A; SIX2; PAX6; CEBPE; ZNF562; ZNF646; TCF3; ARID4B; ZBTB17; KMT2B; IRF3; ELF1; ZNF84; ZNF500; NPM1; MEOX1; BRF2; POU4F3; RNF14; ZNF200; BTAF1; TAF9B; ETV4; ZBTB18; E2F8; HIVEP3; CREB5; THRAP3; FOXF2; ID3; TBX6; BLZF1; MEF2A; ZNF668; ZFX; SRF; HMGXB4; NCOA6; PSPC1; SREBF2; CDC5L; ATF2; SOX9; SETDB1; ARNTL2; FOXC1; TAF10; TRIM27; ZNF444; ZNF426; HAND1; SMAD4; FOXF1; ZSCAN2; ZNF202; YAF2; GMEB2; ARID5A; KLF6; MEIS2; NPAS2; TCEB2; FOS; STAT1; TGIF1; ZNF551; ESRRB; HMBOX1; VAX2; ZNF688; PSMC3; TRIM16; FLI1; WIZ; ZBED4; COPS5; SETD2; MTF1; MYT1; ARID3A; TLE4; SETD3; HINFP; MYOG; AIP; MSX1; SALL1; CNBP; ZNF692; MBD3; ZNF227; ARL2BP; MED1; ZNF74; POU2F2; MZF1; RBL1; ZNF473; RAD21; SP140L; ZNF408; CTBP2; CRYM; CBX4; DR1; RNF2; BTF3; HIVEP1; DMTF1; HBP1; NONO; ZNF512B; ENY2; THRA; ZSCAN12; BAZ2B; TRIM32; NFKB1; ATF3; SP100; SNAPC4; RXRA; URI1; KLF7; INSR; HDGF; PRDM4; JUP; IRX4; SMAD1; ATF6B; TTF1; HMGB1; ZNF32; TAF1A; BLM; POU3F2; UBE2I; TCF15; NRF1; TMF1; FOXM1; HLTF; CBFB; UBP1; CHD9; ID1; CCNE1; CHD1; ZNF419; ZMYND11; IRF7; APEX1; ZNF654; E2F6; HOXC6; MTDH; SFMBT1; HLX; MYF5; SP110; MTA1; CREG1; TFAM; NFIB; MAML1; ZNF354A; ERBB4; KAT6B; ENO1; ZNF536; RNF111; RCOR3; SOX11; BTG1; MEIS1; PAXBP1; EYA1; SOX10; TRIM24; CCNC; NR2F2; ZBED1; ETV5; MTA2; ZBTB16; IRX5; CTBP1; CHD8; TCF4; MECP2; CREB1; TEAD4; MED24; SIM2; HMGN3; RXRG; EP300; FOXA1; ZNF177; ST18; ERG; ZSCAN16; TLE2; PPARGC1A; TCF20; ELF5; ZNF468; CALR; NFIC; ZNF226; RBBP4; ESRRG; HSF2; HEY1; MED6; ZNF134; ZNF83; SAFB2; TOX3; DACH1; PAX5; HOXC4; STAT3; ZNF91; HMGA1; FOXD1