Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50246	Pyrazolanthrone	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	395	ADRB2; PPARG; WWP1; KDM5A; ZFPM2; ZNF331; KLF3; SSBP2; GATA2; MAX; MEF2C; ZNF701; NEUROD1; NFX1; ZFY; LIMD1; TWIST1; BRWD1; SMARCA1; ELF3; PIR; CEBPD; ZNF623; NR2F1; ZIM2; SOX13; ZNF131; ZNF132; LPIN2; PKNOX2; RNF111; NCOA2; TXNIP; TAF4; SSX1; ZNF253; PEG3; NR1H2; ZNF264; MKL2; ZNF135; ZNF528; CAPN15; GRHL2; EMX2; BCL11B; SKI; ASH2L; ZNF629; PNRC1; NR0B1; OVOL1; ZNF552; THAP1; TCF21; TEAD1; ZBTB25; TBP; HMG20A; ZFP37; ZNF273; ZBTB3; NANOG; SOX18; TFE3; FOXJ1; RARA; ZNF225; ARID3B; ZNF217; KDM5D; HR; SOX17; PLAGL1; NR5A2; LIN28A; ZKSCAN8; ZNF614; REST; TAF12; POU6F1; ZBTB20; WT1; ZNF112; ZNF695; ZNF432; SUV39H1; PKNOX1; NRBF2; ZNF175; TBX1; ZNF813; PIAS2; BRPF1; TERF1; ZNF473; SOX21; PRDM5; WHSC1L1; RREB1; MLLT1; SSBP3; CIITA; ZNF492; ZNF510; ZNF180; IL16; TCF7; AEBP1; IKZF2; ZNF423; CBFA2T3; ZNF227; TCF12; RFX7; PLAGL2; E4F1; ZNF391; NFATC1; SMARCA5; BHLHE41; BACH1; TFAP4; AFF4; ZNF764; ZBTB6; ZNF835; STAT2; HDAC6; ZNF506; KAT7; ZNF507; KLF10; PRDM1; MLXIP; ZKSCAN7; RFX2; PROP1; PAX4; EZH1; TFAP2B; ZNF442; BNC2; FOXE1; TRIM32; ZNF286A; TGIF1; ZBTB7C; TP73; CREM; HIC1; MAK; PIAS4; CD3D; THAP10; MECOM; TBR1; HNF4G; CBX8; PEX14; SPIB; ESR1; ZNF544; CITED2; CTCF; ZNF550; MGA; KLF11; OVOL2; CDX1; SP1; SUPT7L; AGO2; TCEA2; ZNF571; DNMT3B; MDM2; ZNF223; EGR2; PITX1; IFNB1; TRIP11; SKIL; HSF4; JARID2; LEF1; TULP4; FOXG1; SAFB; ZFP2; NR4A1; PLAG1; ZNF274; ZNF282; PRMT2; HDAC11; ZNF226; DDX17; PPARD; IRF1; KLF4; HOXA3; BCOR; ZNF460; HDAC4; KAT6A; FOXD3; CRTC1; RELB; PRKDC; PHIP; ZNF214; TRIM28; NR1H4; SMAD2; CSDC2; MEIS2; ZNF329; ARRB1; NFIL3; SAP30; ADNP; ZSCAN18; MYBL2; ZNF780B; EHF; NFATC4; FOXB1; EHMT1; SALL2; IRF2; ZNF236; ZNF85; ZNF157; EYA3; ZNF419; HSF1; CDK9; YAP1; SOX5; PBXIP1; NFE2L2; AHR; HOXD1; TOPORS; LHX3; HIVEP2; TGS1; MEIS1; BARX2; ZNF91; TFAP2C; ZNF304; ZNF222; MEN1; ELK4; TMF1; HNF1B; SMAD9; NKX2-2; ZNF674; RXRA; ING2; ZNF556; THAP11; ZKSCAN4; FOXO4; ZNF682; NFYA; GATA6; ZNF75D; PGR; SAP130; OSR2; TRIM33; EPAS1; UTF1; FOXH1; ZBTB24; ZBTB44; SUV39H2; SMARCA2; NKX2-1; HOXC5; ZHX2; NFAT5; ZNF117; JAK2; FOXN2; RERE; HHEX; FOXL2; CAMTA2; ELK1; MYBL1; CARF; BATF; POU5F1B; MYF6; MNDA; IRF5; ZNF721; ZNF573; ZNF93; BRCA1; RUNX1; AATF; TBX2; RSF1; AFF1; RCOR1; RNF141; ZNF337; UBE3A; PPP1R13L; BBX; ZNF350; ZNF710; ZMYND8; STAT5A; PRDM14; NCOA1; ZFP36L1; ZNF587; LHX6; RBPMS; E2F5; LYL1; ZIC3; HIC2; E2F2; GATA1; MYB; SIM1; DPF2; ZNF165; KLF9; NR3C2; KLF2; ZNF160; EGR4; TCF7L2; CARHSP1; MAF; HIPK3; RUVBL2; ELF5; TSC22D3; POU2AF1; ZNF33B; GFI1; MED12; CUX2; PAX6; GATA3; ZNF574; ZNF606; TRIM22; TLE4; ZNF107; NCOR1; ZNF665; TCF7L1; MED7; CTNNB1; CNOT1; MITF; NPAT; IRF4; HLF; CBX7; GABPA; RORA; BANP; HMGB3; MYCN; MAGED1; YBX2; ZNF468; EYA2; EGR3; MYCL; TTF2; FOXD1; ZFP36L2; ZEB2; HOXB7; AR; IFI16; NR1H3; TFDP2; NR4A2; TSC22D1; ETS2; TFAP2A
Down-regulation	410	DRAP1; NRIP1; SCAND1; ATF1; ATF6; RHOA; ILF2; LOXL2; HOXA5; DEK; PSMD9; HDAC2; CDK2; ZNF589; ATF5; NKRF; MAZ; RBM39; RFX5; GMNN; ARNTL2; ITGB3BP; AIP; PTTG1; ATF4; FOXO3; CCDC59; RNF4; CSDE1; RBBP8; DNMT1; CBX3; TAF6; NCOR2; ATF2; PHF1; SF1; TAF10; PCGF1; CARM1; FLNA; DNAJC2; GTF3A; RAN; PMF1; SUPT4H1; PFDN5; TADA3; SRF; GMEB2; STAT6; C1QBP; MYC; SP100; CNBP; ZNF24; KDM2A; BRD8; FOXJ3; SUMO1; HNRNPD; VPS72; ETV1; ZNF580; USP16; MED24; TSG101; PATZ1; XRCC6; VEZF1; ERCC3; CDC5L; SMARCD1; KMT5A; PDLIM1; CREB5; HOXA4; TAF11; HOXA10; SREBF2; DLX2; ZNF444; GTF2IRD1; CREB3L2; HMGXB4; ZNF140; TSC22D2; RNF138; HOXA7; ZFHX3; SUB1; GBX2; CBFB; ZBTB7A; MTF2; VSX1; JUND; BCL6; MYT1; CERS4; RNF10; SP140L; HMGB1; HOXA6; TDP2; NFRKB; MDFI; SATB2; APBB1; ZBTB11; BRD4; BIRC2; DEAF1; DAXX; ENY2; CRX; WHSC1; EDF1; MED13; ZNF146; TCF25; ZNF593; PEX2; PSMC3IP; TRIB3; ZMIZ1; BCL3; ARID5A; MED21; WWC1; SMAD7; ZMYM2; SNIP1; SMARCC2; ACTL6A; HCFC2; POU3F2; ZNF22; CCNC; NOC2L; HIRA; NFKB1; HMGXB3; ARID1A; NCOA6; CBX6; KLF6; ZNF446; ARL2BP; HABP4; PIAS1; NSD1; PTRF; NFKB2; ARID5B; CREB3; HOXB5; CENPF; UBP1; ID2; CHD3; SP110; FUBP1; ZFHX4; RNF6; PBX3; SPEN; ERBB2; BRD2; SIRT7; HDAC3; UBE2L3; ZKSCAN5; LITAF; ZNF410; BTAF1; SOX9; ARNT2; CTBP1; MED1; HBP1; RXRB; YWHAB; HOXB3; PCGF3; TBL1X; MED17; GATAD2A; CEBPZ; BCLAF1; KLF13; BTF3; SRCAP; HDAC1; RFC1; SERTAD2; ZNF668; MTF1; TAF9; ZNF536; RYBP; NPM1; UIMC1; ING3; YAF2; MLX; TBX10; ACTL6B; ZNF768; RFXANK; RFXAP; ALX3; PRDM4; TRIP6; KLF7; TUB; PRRX2; HDGF; NAB1; ZBTB17; MED27; ZZZ3; RING1; FOXM1; BATF3; ZNF646; SALL1; MXI1; THRAP3; MSX1; HOXD9; NPAS1; ETV5; PA2G4; CDYL; TBX6; MTDH; KAT2B; VAX2; ID3; ELK3; ZNF232; ZNF35; EZH2; ZNF426; ENO1; MYNN; HLTF; SNW1; NFIB; SOX12; CEBPE; ZNF408; SMAD1; ZNF467; NHLH2; CHD1; PAXBP1; SMAD4; SIM2; GMEB1; HTATIP2; CUX1; CCNT1; TAF5L; KLF1; DACH1; TFAM; ZNF652; TCF4; BRCA2; MEF2D; C1D; VGLL4; TEAD3; TRAK1; SMAD3; ZNF263; CHD4; TCF20; CENPB; SP3; RBPJ; ARID4B; ETV6; RBBP5; ARID4A; CNOT2; MEF2A; GLI3; MLLT10; ZHX3; PAWR; ZNF562; ZNF692; HMBOX1; ZNF512B; PSMC3; NEDD8; THRA; JUP; SUPT6H; SHOX2; ESRRB; ZKSCAN1; YBX1; TBX3; YBX3; ATN1; ESRRG; KDM5C; CEBPG; ZNF12; JUNB; POU2F1; DMTF1; SMARCB1; ETV4; CHD8; COPS5; THAP4; ZNF202; ZNF224; POU2F2; IRX4; ISL1; MYF5; DR1; INSR; RXRG; ZNF84; SFPQ; CREG1; ZNF133; SMARCE1; ZNF266; ZBTB1; ZNF248; ZNF3; STAT1; ZNF45; CHD7; ZNF654; MEOX1; NR2F2; ZIC1; CRYM; ZMIZ2; PSIP1; ESRRA; TRIM29; ID1; SCMH1; SIX2; MED23; TGIF2; CRY1; COPS2; TULP3; HMGA1; NELFB; RBFOX2; UBE2B; CRK; ZBTB43; BLM; ERF; MTA1; LZTR1; ZNF281; ZBED4; ELF1; MMS19; WWTR1; KAT6B; PHF20; ZBTB18; MED6; EHMT2; RNF14; TAF9B; VDR; CREB1; BCL11A; DLX5; IRX5; BMI1; FOS; ARNTL; MYRF; HIVEP1; TBL1XR1; FOXF1; SREBF1; FOSB; EN1; APEX1; SOX11; E2F8; INSM1; MBD2; CEBPB; IRF8; TERF2; BAZ1A; NKX3-1; TP63; HMGB2; ASCL1; SOX2