Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50183	Nalbuphine	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	361	ADRB2; SSBP2; KDM5A; WWP1; CREM; KLF4; ZFY; ZFPM2; GATA2; NRBF2; BRWD1; KLF3; NCOA1; ZBTB24; BRPF1; SOX3; ZNF701; NEUROD1; MAFB; TFAP2B; SKI; CEBPD; SOX13; EGR2; ZNF227; MAF; TBP; ZNF710; EGR4; EGR3; ATF7IP; ZNF623; ZNF180; SOX18; ZFP36L2; ZNF331; IKZF2; NR1H2; PLAGL1; LIMD1; KDM5B; TFCP2L1; THAP1; ZNF85; LPIN2; SND1; ZNF813; ZIM2; ZNF225; ZNF692; ZNF571; SSX1; ZNF200; ZBTB20; NFATC1; FOXE1; ZNF696; ZNF573; KMT2B; ZBTB6; ZBTB44; ZNF281; STAT5A; ZBTB7C; SKIL; PITX1; TDRD3; PITX2; ZNF253; POU6F1; ZNF112; NFKBIB; BACH1; ZNF93; TEAD1; NKX2-1; ZBTB25; PRDM5; PRDM10; NR4A1; ZNF432; RARA; NR2F1; BAZ2B; ZNF443; KAT2B; ZNF117; ZNF507; FOSL2; BNC1; RFX7; CBFA2T3; PRMT2; PPP1R13L; HIC1; SUV39H2; ZNF695; LMCD1; SAP130; TFAP2C; ZBTB3; BCL11B; AGO2; ZNF226; ZNF75D; IRF5; EYA3; NCOA2; TBX19; PRDM1; ARID3B; KLF8; PIAS3; NCOA3; BCOR; OVOL1; HR; CREBL2; RFX1; ZNF334; NANOG; STAT2; SUPT7L; BRIP1; ASCL2; ZNF557; HIC2; GATA1; ZBTB39; TCF21; NPAT; MLXIP; POU1F1; ELF3; GLI2; ZNF23; TRIM33; MXD1; TAF7L; LIN28A; ZFP30; SMARCA2; ZNF215; ELF5; KLF12; TSC22D1; NFYC; ZNF672; MYCL; SUPT5H; PROP1; DDX17; NSD1; VGLL4; TAF12; FOXD3; NR3C2; MAX; OSR2; FOXJ2; NFE2L2; CAPN15; MYF6; ZNF780B; TBX1; MYBL1; ZEB2; BNC2; NFAT5; ZNF764; ATOH1; ZKSCAN7; KDM5D; ZNF274; IRF6; ZNF33B; ZNF157; RORA; CUX2; CAMTA2; MAK; ZNF235; ZFP37; ZNF614; TFE3; HCFC2; SMARCA5; ZNF350; ZNF80; ZNF236; ZNF234; CSDC2; ELK4; ZNF160; CDX1; PAX9; ZNF682; EMX2; SSBP3; ZNF267; ANKRD1; PPARA; RSF1; DDX54; PIAS1; DNAJC1; GFI1B; ZNF35; ZNF286A; BARX2; ZSCAN32; ZNF222; SAP30; ZNF337; NFE2L3; ZNF142; ZNF492; FOXL2; ZNF835; AFF4; SP1; HDAC5; PML; NR5A2; TWIST1; ARRB1; POU3F1; HOXC5; GRHL2; IL16; TRIP11; ZKSCAN4; ECD; PLAGL2; TRIM25; CREBZF; ZNF721; ZNF528; CARHSP1; TAF1D; CTNNB1; MITF; CIC; CDIP1; RNF111; BTG1; MSC; MTF1; TRIM22; BANP; MAFG; PLAG1; PKNOX2; ZIC3; ZNF208; THAP10; GFI1; MED15; AFF2; ZNF273; TCF7L1; USF2; HTATIP2; ZBTB14; CREB3L2; CARF; ZBTB16; ZNF32; ZNF665; RREB1; PURA; ZNF587; GATA6; BRCA1; BLZF1; HIVEP2; ISL1; ING2; TCF25; HSF1; ZNF264; WT1; HESX1; DNMT3B; TOPORS; ING4; RXRA; PEG3; BHLHE41; PPARD; ZNF329; IFNB1; ZNF141; ZSCAN16; PRDM14; PIAS2; PAWR; FOXN2; ZNF175; CBX7; WNT4; MBD2; SOX17; EPAS1; TSC22D2; MYCN; POLR2A; HLF; MAFK; GATA3; ZNF257; ZNF423; PHIP; ZNF611; PRKDC; PRRX1; ZBTB18; TFEC; TXNIP; HMGB3; ZNF552; BHLHE40; TBX21; JARID2; ZNF43; ARID4B; STAT4; MNT; SMAD2; ZHX2; DAXX; CERS4; ERG; AFF1; ZNF532; TRIM24; BBX; RCOR3; RBPMS; TOX; NR4A3; AEBP1; TRPS1; RCOR1; ZEB1; BACH2; HMGN3; GTF2I; AHR; NPAS2; TSC22D3; KLF11; KLF2; ASCL1; NR2F2; EHF; ETS2; ZNF91; MTA1; NFATC3; CRK
Down-regulation	416	SCAND1; DRAP1; NRIP1; TLE1; HOXA5; LOXL2; NR2F6; ATF1; CDK2; ILF2; DEK; HDAC2; RUVBL1; ZNF589; ATF4; NFKBIA; RFX5; ATF6; CDC5L; PMF1; GTF2A2; DEAF1; ATF5; MAZ; DNAJC2; PSMD9; GMNN; RNF4; BRD8; BCLAF1; PCGF1; ITGB3BP; RBM39; PBX1; RHOA; NFATC4; ATF2; WIZ; SNW1; HOXB2; TSG101; NKRF; GTF2IRD1; CERS6; HOXB5; CCDC59; RING1; APBB1; TRIP6; RFXANK; RFC1; DNMT1; ETS1; C1QBP; HDAC3; IKBKAP; APEX1; HOXB6; SFPQ; PATZ1; MGA; HOXA4; RBFOX2; RBBP8; TAF9; VPS72; ZNF580; THAP4; USP21; SMARCD1; KDM2A; PRRX2; HNRNPD; MYC; SUB1; SUPT4H1; CCNH; FUBP1; RNF138; MEIS1; BTF3; SP140L; LITAF; FOXO3; SSRP1; DLX2; USP16; PUF60; ERCC3; VEZF1; HOXA10; NFIL3; BTAF1; COPS2; RAN; HMGXB4; TFAM; ABT1; MLXIPL; MTF2; CTR9; BIRC2; MED27; CBFB; TAF10; CRY1; FLNA; XRCC6; PTRF; TCERG1; TDP2; CCNA2; DPF2; ARID5A; MED20; HOXB3; SP100; NOC2L; AIP; TCF4; BCL3; ZNF408; C1D; HOXA7; MED13; SRCAP; CHD1; PDLIM1; PEX2; NPAS1; HOXD10; STAT6; HIRA; KMT5A; NCOA6; WWC1; WDR77; ACTL6A; ZNF512B; CDYL; PHF20; SERTAD2; ARID4A; HMGB1; TBX10; TEAD3; DDIT3; HLTF; ID3; ALX3; GBX2; ZNF24; ZNF266; THRAP3; ARNT2; ZFP64; ZMYM2; ALX1; SIX1; MED24; GTF3A; ARID5B; CCNC; TRIB3; SOX15; MDFI; KLF6; ID2; COPS5; DLX6; ZNF446; MSX1; SREBF2; PA2G4; EHMT2; VSX1; CRX; CTBP1; TAF6; SUMO1; CHD8; CBX5; PHF1; RUVBL2; SF1; CBX3; TAF11; ING3; BPTF; MYT1; SALL2; ETV4; TAF7; RNF6; TFCP2; PRPF6; PRDM4; ERCC2; ZFHX3; MNAT1; THAP3; MED1; ZNF131; SMAD3; ERBB2; ID1; HOXA11; PAXBP1; FOXF2; ELF1; ZBTB38; YBX3; SMARCD3; NEDD8; ZNF646; PBX3; ZMIZ1; CBX6; SMAD6; IRF9; BAZ2A; JUND; CEBPE; MYNN; PIR; RRN3; ZBTB11; MZF1; HMG20B; CHD4; CHD7; ZNF232; HOXB1; KDM5C; ZNF593; SALL1; SMARCB1; ZMYND8; NR2C1; PTTG1; PSMC3; PCGF3; PMS1; ZNF140; ACTL6B; ZNF768; ADNP2; TOX4; TCEA1; HOXD11; TBX6; TCF20; ZNF562; ASXL1; FOXF1; KAT6A; MXD3; ZNF384; ZNF536; CARM1; PSMC3IP; UIMC1; RAD21; HOXD9; MTDH; ZNF146; ZNF652; ARL2BP; ATF6B; RNF14; CEBPZ; TRRAP; HES1; FLI1; EWSR1; VAX2; TBL1XR1; MED17; CITED1; ZBTB17; MED23; CNOT2; HOXB7; MYOG; BATF3; WWTR1; MEOX1; POU3F2; MYRF; RNF10; CNBP; AES; SATB2; ATF3; ETV1; SFMBT1; TGS1; CHAF1B; NHLH2; EZH2; KAT8; RORC; SP3; JUNB; ETV5; SNIP1; TOB1; ARNTL2; BCL6; MED4; ZNF787; SIM2; MECOM; ZBED1; SMAD7; HOXC10; ZNF576; ARNTL; HOXC4; BRD4; ZBTB1; ZZZ3; ZKSCAN3; ZNF195; BARX1; TADA3; BRD2; POU2F1; MYF5; RYBP; SPI1; DR1; TULP3; ZNF7; ID4; BCL11A; PBRM1; CREB5; ZBED4; CHD9; SOX12; ARID1A; MEIS2; MED6; SPEN; TRIM27; ASH2L; DLX5; FOS; TEAD4; KAT5; SIX2; BAZ1B; SIRT2; UBE2L3; HHEX; TGIF2; RXRG; CREG1; ATN1; KLF7; HIVEP1; CRYM; NCOR2; RBBP4; TCF3; BMI1; SMARCC2; RUNX1; SREBF1; DBP; TRAK1; PSIP1; GATAD2A; NR0B2; TP63; HOXC6; STAT1; NAB1; BLM; ZBTB43; MEN1; FOXA1; SMAD1; NKX3-1; RELA; FOXD1; TFAP2A; IRF8; ZIC1; HDGF; ZKSCAN1; STAT3; TERF2; KAT6B; TRIM16; HMGA2; HMGB2; SAFB2; HMGA1; ST18; CBX4; SIAH2; ZSCAN31; MEOX2; INSM1; POU2AF1; FOXC1; TAF9B; SOX9; TGFB1I1; FOXO1; TRIM29; TBX2; NR3C1; SOX2