Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50171	Meclizine	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	355	ADRB2; KDM5A; ZFPM2; WWP1; SSBP2; SKI; CREM; NEUROD1; ZNF701; ZBTB20; GATA2; NRBF2; ZNF623; TEAD1; TBP; KLF3; BRWD1; NFX1; SSX1; CEBPD; SMAD5; SOX13; NFAT5; EGR2; ZNF131; NR5A2; ZNF331; NR1H2; LIMD1; ARNT; ELF3; REST; ZBTB6; ZNF573; ZNF835; ZBTB3; CTCF; PRDM1; BNC1; ZFY; TMF1; SOX3; ZIM2; ZNF764; ZBTB24; ZNF273; ZNF75D; NR1H4; SAP130; SKIL; ZNF117; TBX3; L3MBTL1; MAFB; PEG3; HIC2; NCOA2; WHSC1L1; HMG20A; MAF; SOX18; SMARCA1; FOXN2; ZBTB7C; ZNF107; HDAC7; ZNF200; ZKSCAN4; ZNF180; GON4L; TSC22D1; ZNF813; PIAS1; TBR1; NR3C2; SND1; ZNF148; PROP1; RSF1; SMARCA5; FHL5; MLXIP; OVOL1; CHD4; BACH1; RFX7; ZNF248; KDM5D; NANOG; ZNF721; HLX; AEBP1; TCF21; ZNF135; ZNF695; TAF12; ZNF219; PITX1; CARHSP1; HDAC11; STAT2; ZNF124; AHR; FOXE1; AR; RNF111; ZSCAN16; ZNF692; ZNF629; ING4; ZNF264; MKL1; ZNF136; ZNF85; TFE3; KAT2B; CHD2; ELK4; NLK; FOXN1; IKZF2; FOXJ2; HLF; TFAP2C; ZNF492; RBBP5; PHIP; MED7; PRDM5; STAT5A; CARF; NPAT; KAT6A; BLZF1; ZNF571; UBE2B; NFIB; TAF7L; ZNF160; MXD1; MITF; ZNF665; FOXD3; CD3D; TFCP2L1; ZNF224; GLI2; TAF4; FOXA1; MYBBP1A; PPRC1; ZNF696; ZNF440; ZNF254; PAX4; CBX7; ZNF215; EYA3; ZNF334; NR2F1; TCF7; BCOR; POU2F3; ZNF214; TOPORS; TRIM24; SUV39H2; BRDT; ZBED2; TXNIP; SETDB1; ZNF770; ZFP37; POU1F1; TRIP11; BHLHE41; CAMTA2; MYBL2; CREBZF; ZNF34; RBL2; KMT2B; TBL1Y; PIAS3; ZNF33B; THAP10; MAX; GRHL2; ZNF552; ZNF223; ZNF112; ZNF507; ZSCAN9; MAK; NCOA3; SALL2; TRIM33; NKX2-1; PLAGL2; ZNF236; HOXC5; EPAS1; ECD; SP1; ZNF142; CBFA2T3; RB1; MYT1L; RERE; PAWR; POU5F1B; GATA1; AFF2; ZNF528; ZFP36L2; CRTC1; ZKSCAN7; SUV39H1; HHEX; PBXIP1; EGR4; ASH1L; ING2; ZBTB39; ZNF225; TULP4; FOXO3; ZNF212; ZNF222; TRIM32; ZNF780B; AFF4; NR4A1; PKNOX1; ZBTB44; EMX2; TFAP2B; PEX14; ZEB2; ZNF205; CTNNB1; ZNF674; KLF11; WT1; DDX17; RBPMS; ZNF587; ZNF329; ZNF350; ZNF611; SOX21; BBX; SAFB; KMT2D; NFE2L2; SREBF1; BTG1; ATF7IP; CIITA; CUX2; TRIM25; MBD4; NCOR1; SMARCD3; GFI1B; KLF5; PNRC1; PLAG1; FOXJ1; LIN28A; NKX3-1; TBX2; LZTS1; FOXI1; PITX2; TRIM22; ZNF710; BCL11B; SMARCA2; UBE3A; PRKDC; ZNF682; ZNF432; ZNF208; ZFP36L1; ESR1; KAT7; PHF20; PBRM1; MYBL1; SFMBT1; TGS1; NFE2; SOX17; NR1D2; DNMT3B; MMS19; YBX2; LPIN2; SOX5; IFI16; GFI1; LYL1; PPARD; EHF; MEIS1; PGR; MED15; GATA3; URI1; RARA; KLF4; BRIP1; ZNF415; TFEC; LHX6; SAP30; ZNF3; NCOA1; CREBL2; MAFF; ZNF304; VPS72; MED4; ZBTB38; ZIC3; ZNF267; HIPK3; REL; STAT4; AFF1; IRX5; BACH2; BNC2; ATF3; TERF1; HEY2; ZNF443; JUN; ZNF43; ZNF12; FOXO1; TRPS1; EGR3; TFDP2; NR4A3; NFE2L3; TFAM; HIRA; KLF10; ETS2; TAL1; MEOX2; TFAP2A; ZNF586
Down-regulation	443	DRAP1; SCAND1; HOXA5; LOXL2; NRIP1; TLE1; ILF2; ATF1; RNF4; RUVBL1; PSMD9; ZNF589; EDF1; HDAC2; MAZ; ATF6; RHOA; GTF2A2; THAP11; CDK2; RFX5; PCGF1; AES; SUB1; ITGB3BP; ATF5; CCDC59; GTF3A; RBM39; DEK; CDC5L; WIZ; DNMT1; NKRF; TADA3; TAF10; ATF4; THAP4; PMF1; DEAF1; BCLAF1; NOC2L; HOXA4; TBX10; BRD8; RFXANK; RNF138; SF1; TCF3; TAF6; NELFB; MED27; ZNF580; SERTAD2; HDAC1; CSDE1; MED24; AIP; C1QBP; ZNF146; IKBKAP; SNW1; ZNF140; SRF; BTF3; BCL3; CBX3; ZNF593; HOXD10; PHF1; HOXA10; USP21; KMT5A; PRRX2; USP16; SLC2A4RG; PBX1; CCNH; RAN; CNOT3; CARM1; SP140L; SIM2; HOXB6; TSG101; SETD3; FLI1; PCGF3; GBX2; DLX2; ARNTL2; CEBPG; HABP4; MYC; HOXA7; SP2; CTBP1; CDYL; BIRC2; SMARCD1; DLX6; HNRNPD; SUPT4H1; APEX1; IRF3; RNF6; RING1; ZFHX4; CENPF; FOXJ3; NFYC; TAF9; CRYM; ZNF24; ATF2; MSX1; CBFB; MXD4; COPS5; SOHLH2; GMEB2; COPS2; SUPT6H; ZNF446; RUVBL2; TAF11; TAF7; NCOA6; WHSC1; MED16; ENY2; TGFB1; CCNC; HOXB3; SMARCB1; PTTG1; KDM2A; HOXB2; FOXN3; MDFI; WWC1; CIZ1; PEX2; SREBF2; ERCC2; NFRKB; ERCC3; PSMC3; NPAS1; ATN1; ID2; SHOX2; TBX6; MNAT1; THRAP3; PDLIM1; ETV1; MTDH; ZMYM2; SOX9; CRX; ZMIZ1; ZBTB18; MED13; HMGB2; JUND; ZNF45; ZNF266; XRCC6; YEATS2; TP53; ZNF76; CTR9; ZNF408; RAD21; MAML1; SIX1; MLX; ERBB2; PMS1; MED20; RNF10; RFC1; CRY1; ZBTB7A; TEAD3; VAX2; HOXB5; TEAD4; ARID1A; ARID5A; NEDD8; BATF3; ZNF536; MYF5; ERF; HOXD9; UBE2L3; ZNF562; ID1; SATB2; MTF2; CHD1; HMGN3; PAXBP1; SIN3B; ZBTB11; ARNT2; CERS6; DAXX; EHMT2; ELF1; HOXA11; TCF25; FLNA; SP110; SMAD3; ZBTB17; CENPB; SRCAP; PRPF6; TDP2; RXRB; KDM5C; CREB3L1; ARID5B; PBX3; ZFP64; BRD2; HOXA6; MYNN; HOXB7; MYOG; TFCP2; SMAD7; FOXD1; ZFHX3; RBBP4; MAPK8IP1; MED1; BRD4; ZBTB1; UBP1; VGLL4; ZNF768; ZNF576; ZNF668; THAP3; ZNF84; TAF1C; DLX5; SUMO1; RBBP8; TRIB3; ACTL6A; BCL10; POU3F2; SAP18; LMCD1; MEF2D; ZNF177; ARID4A; MBD1; JUNB; SPEN; HDAC4; RCOR1; IRF9; NHLH2; HOXB1; ZNF155; MXD3; ZNF512B; KAT8; FOXM1; BPTF; CBX4; MZF1; TRIM27; HEY1; NR2C1; ID3; HOXC6; RARB; DPF2; SP3; ELF4; ATF6B; LITAF; UBE2I; YBX3; EN1; ZNF232; ESR2; HMGXB4; PBX2; ZZZ3; BCL11A; BAZ2B; IRF7; HAND1; PRDM4; SSRP1; MEIS2; CTBP2; PSPC1; CHD3; PAX6; FOXO4; EGR1; TOX4; VEZF1; HMGA1; HDGF; PHF8; SP140; ZNF444; TRIP6; ZNF302; KLF7; MED21; IKZF5; MYRF; TRIP4; ASH2L; MEF2C; DNAJC2; NPM1; SMAD2; CIR1; SALL1; TGIF2; YBX1; ABT1; FOXF2; CEBPB; DR1; BRF2; UIMC1; RUNX1; CEBPA; TOB1; NFE2L1; SUPT3H; TRIM16; ZNF639; BANP; SOX12; CEBPZ; TWIST1; CBX5; ZNF7; TRAK1; STAT1; ZNF426; CALR; FUBP1; MED6; ENO1; POU4F1; HOXD11; NPAS2; DMTF1; INSR; MTA1; TERF2; RYBP; HOXB13; RELA; PSIP1; PSMC3IP; FOSB; RNF14; ZNF268; NFKB2; BARX1; SP100; CNBP; ZNF468; SIX2; NONO; MED17; ZNF195; RXRG; ZHX2; ERG; ING3; ZMYND8; TBL1X; ZNF32; MEOX1; MEF2A; RBBP7; HOXD3; TCF4; ZSCAN18; TBL1XR1; FOXF1; PREB; PA2G4; ARNTL; ZIC1; KAT6B; MTA2; CREB1; SMAD6; TAF9B; FOS; HMGB1; PTRF; PQBP1; SAFB2; DDIT3; TSC22D4; BMI1; ETV4; TCF7L1; ZNF189; HOXD1; CREB5; STAT3; ASCL1; KLF2; FOXA2; PPARGC1A; TGIF1; BCL6; TCEB2; IRF8; SIAH2; ZNF354A; HDAC9; FOXG1; ST18; HOXC10; E2F8; GATAD2A; PAX5; TRIM29; SOX11; EYA1; SOX2; NR3C1