Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50166	Loperamide	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	360	ADRB2; PPARG; ZFPM2; KLF4; KDM5A; CREM; SSBP2; WWP1; SOX13; KLF3; MEF2C; GATA2; ZNF701; ZNF331; SOX18; ZIM2; EGR2; ZNF131; BRWD1; ZBTB20; SKI; NR1H2; TBX1; PKNOX1; CAPN15; HHEX; BARX2; ELK4; ZBTB24; MAF; MLXIP; SMARCA1; HDAC11; MYF6; PITX1; ZFY; ZNF623; SAP130; ZNF200; TRIM33; PRMT2; FOXE1; NEUROD1; SSX1; TFCP2L1; BNC2; NR1H4; PKNOX2; ZNF85; HDAC6; OVOL1; MKL2; EMX2; IRF5; SMARCA2; WHSC1L1; PEG3; CDK8; RARA; LIMD1; NKX2-2; ZNF764; NR2F1; SAFB; NFATC1; CBFA2T3; ZNF226; ZNF696; NR4A1; BCL11B; ZSCAN32; NR5A2; HIC2; PHIP; PITX2; BRPF1; KDM5D; PAX9; NCOA1; NRBF2; NANOG; SOX17; BACH1; POU6F1; NR3C2; TSC22D1; ZNF112; FHL5; ZBTB25; MAFB; GATA1; HLX; ZNF180; CUX2; ZNF329; ZNF813; NR0B1; ING2; OLIG2; ZNF225; HR; ZNF550; HIC1; MYBL2; EGR3; TRPS1; CTCF; ZHX2; MEF2A; SKIL; PML; PRDM1; EP300; TGFB1; HDAC5; TFAP2B; MAFF; FOXJ2; ZNF273; ZNF350; ZNF34; ZNF264; ZNF211; TCF21; ELF3; NFE2L2; NCOA3; SP1; CHD2; ZNF571; NFAT5; ZNF557; HNF1B; EPAS1; ZBTB6; ZNF324B; STAT2; JUP; MYOD1; ZEB2; KAT6A; LPIN2; FOXL2; POU1F1; RFX1; REST; FOXO1; ARID3B; PAX8; VGLL1; HLF; ZNF236; AEBP1; DDX17; TBP; HOXD13; EHF; TULP4; POU5F1B; TMF1; ESR1; ZNF432; ZNF710; ZNF665; PSPC1; RFX2; NKX2-1; ZNF492; HOXC5; ZNF135; MAX; HOXB13; ZNF267; TLX1; LIN28A; ZBTB3; CDK9; LHX3; AGO2; MNX1; FOXJ1; ZNF419; ZNF33B; CHD9; THAP10; SRF; ZBTB16; DNMT3B; DNAJC1; RRN3; PLAG1; POU2F3; MITF; E4F1; RREB1; ERG; THAP1; ZNF205; VGLL4; ZNF157; ZNF587; ZNF215; SAP30; EYA3; NPAS2; ZNF304; MYBL1; AFF1; ZBED2; YBX2; AFF4; CD3D; ZNF500; TRIM22; BNC1; CREBZF; TRIP11; MED12; ZNF695; ZNF778; CBX7; GRHL2; KAT2B; ZNF175; TCF7L1; RBPMS; LZTS1; RAX; NPAT; PLAGL1; ZNF217; ZNF528; SNAI2; HDAC7; CAMTA2; SND1; SSX3; BHLHE41; HMG20A; AHR; ASH2L; TRIM28; CLOCK; FOXN3; TFE3; OSR2; GABPA; SOX21; NKX2-5; PRRX1; TDRD3; BRCA1; ZNF148; SMARCA5; BTG1; WT1; ZNF263; ZNF721; ZNF160; KLF2; TSC22D3; ZNF551; NFE2L3; TCF15; LMCD1; MAK; FOXA1; HTATIP2; EBF2; ZNF91; CITED2; ZBTB14; KLF10; ELK1; PRKDC; ZNF787; PIR; ZNF93; ELF5; CREB3L2; TTF2; RNF111; TAF4; STAT5A; MSC; ZSCAN16; NCOA2; NFIC; MED15; BRIP1; BHLHE40; IFNB1; ZNF606; HEY2; AATF; ZSCAN31; ZNF430; HSBP1; SIRT2; PBRM1; ZNF468; ELF4; CARHSP1; RCOR3; RERE; ETS2; IRF6; PRDM14; HSF2; PAX6; ZSCAN18; CEBPD; GATA3; ZNF32; TBX21; RORA; TFAP2C; POLR2A; IRF1; TCF7; KLF11; TERF1; IRF4; PCGF2; ZFP36L2; BCOR; MECOM; ZNF532; NFIB; NR4A3; AR; GATA6; KLF5; CREBL2; TOPORS; SPIB; UBP1; STAT4; TXNIP; FOSB; ZNF611; ZFP36L1; ZNF134; RSF1; CTNNB1; MEOX2; BBX; NR4A2; ZNF423; EN1; ZNF43; ZNF83; TGFB1I1; ASCL1; KLF9; HIPK3; MYB; HMGN3; TFAP2A; PSIP1
Down-regulation	407	SCAND1; HOXA5; TLE1; NR2F6; NRIP1; ATF1; PSMD9; CDK2; BRD8; ATF6; HDAC2; NKRF; LOXL2; EDF1; RFX5; DEK; ZNF589; GTF2A2; RNF4; ATF5; CCNH; ILF2; GMNN; PCGF1; THAP4; RBM39; TCEA2; CARM1; MAZ; PMF1; ITGB3BP; CDC5L; PATZ1; TSG101; RBBP8; DNMT1; DEAF1; AIP; PTTG1; CERS6; GTF3A; BTAF1; MGA; WIZ; HMG20B; TAF10; ZNF593; BIRC2; PHF1; ATF2; HOXA10; MED24; FUBP1; HOXB2; MED27; MYC; RFC1; IKBKAP; PBX3; FOXO3; ASXL1; SUPT4H1; KDM2A; CCNA2; VEZF1; SMARCD1; HOXA4; VPS72; USP21; ZNF266; TOX4; RELB; HOXB6; HOXB5; DLX2; PHF20; ZBTB17; ZNF410; ZNF140; NFKB1; ZNF22; NELFB; ZNF335; NOC2L; CCDC59; HOXA7; JUND; UBE2L3; NCOA6; SERTAD2; WWC1; DACH1; GTF2IRD1; CXXC1; CBX3; GTF2A1; NFRKB; MED13; APEX1; PDLIM1; SIN3B; HOXB3; DLX6; DNAJC2; CAMTA1; PEX2; ARNTL2; RAN; PRPF6; ZMIZ1; TRIM32; HDGF; NHLH2; BTF3; ZNF536; ZFP64; URI1; ELF1; SRCAP; PCGF3; SMAD7; C1QBP; TTF1; CHD8; CREB5; FOXF1; TFAM; MXI1; KLF7; MTF2; SUB1; TAF9; HDAC3; TUB; SP2; MEIS1; RAD21; ENO1; MTDH; PA2G4; BRD4; HIRA; CDYL; FOXP3; SPEN; ID3; GBX2; NFIL3; PFDN5; JUNB; ARID5B; ATF4; FHL2; CHD7; ZNF580; DAXX; RFXANK; PRDM4; CBFB; CALR; ARNT2; RFXAP; PRRX2; MYRF; STAT5B; RBPJ; MED14; ETV4; ARID1A; KAT8; DDIT3; MXD4; ID2; RNF10; ZNF562; THAP3; TAF7; HAND1; ZBED1; SOX9; FOXJ3; ABT1; ZNF232; ERCC3; MED20; MLXIPL; ZNF195; HLTF; KAT5; ARID5A; YAF2; TRIB3; ZBTB11; FLNA; ZFHX4; NEDD8; TRIM29; COPS5; MSX1; ZNF146; CTBP1; ZNF426; E2F5; SSRP1; CSDE1; MZF1; SNW1; GMEB2; HOXD10; TRIM27; BCL3; ZBTB38; IRF9; ZBTB18; ZNF646; EHMT2; UIMC1; ZNF219; RELA; SP100; TADA2A; TBL1X; HOXD9; ACTL6A; ERBB2; SMAD4; THRAP3; BATF3; USP16; CHD1; NCOR2; MLLT10; ACTL6B; DR1; SOX12; SF1; CEBPE; ENY2; SALL1; HMGXB4; MDFI; ZNF24; MXD3; ZNF3; ETV1; STAT6; TRIP4; YWHAB; RNF14; SMARCB1; HMGXB3; PUF60; TBX6; RING1; LITAF; BCL11A; ZNF408; CTR9; MED16; ZNF189; THRA; CITED1; ZNF84; BRD2; POU3F2; PARP1; SOX15; MNT; ZMYND8; FOS; SHOX2; KDM4A; FOXK2; ZBTB7A; AES; NFATC4; SREBF2; SP3; SOHLH2; ATF6B; TRAK1; XRCC6; EZH2; NFKB2; ING3; UBE2B; CCNE1; SREBF1; SMARCC2; SUMO1; ZNF668; RARB; FOXM1; ARL2BP; HNRNPD; SFPQ; SP140L; CIZ1; SMAD3; MBD1; GATAD2A; ZNF177; PPP1R13L; SATB1; WDR77; MED21; ZNF652; ZNF202; CCNC; ADNP2; ISL1; ZNF12; DLX5; DMTF1; KDM5B; MYNN; CEBPZ; SP110; ZNF512B; TCF4; FOXF2; TCEA1; HMGB1; CRYM; RUNX1; CNBP; ID1; EWSR1; HDAC1; SCMH1; E2F3; SNAPC4; BCL6; PREB; ATF3; PHOX2B; YBX3; WHSC1; BRD3; PEX14; YEATS4; CASZ1; MLX; MTA1; TAF11; RBBP4; CHD4; TDP2; NKX3-2; TRIP6; NR2C1; KAT2A; JARID2; NAB1; HINFP; KMT5A; STAT1; CBX4; YBX1; MYBBP1A; GLI3; TBX3; RYBP; BANP; RBBP7; LZTR1; TFEB; FOXD1; C1D; DPF2; PBX1; MED6; CREG1; CEBPB; TCF7L2; KLF6; PAWR; TOX3; KAT6B; TAF1D; HOXC6; BMI1; VDR; SIAH2; ZBTB43; SIM2; PSMC3IP; TAF9B; ST18; MNDA; HOXB7; YAP1; HMGA1; MBD4; CRY1; FOXG1; NFE2L1; FOXA2; IRF8; TP63; TRIM16; LEF1; SOX11; ZIC1; ZKSCAN1; CREB1; SOX2