Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50150	Jak3-inhibitor-v	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	344	ADRB2; KDM5A; KLF3; NEUROD1; BRWD1; WWP1; ZNF253; SMARCA1; SKI; GATA2; NRBF2; NFX1; CEBPD; MDM2; ZNF701; EZH1; CREM; TXNIP; CIR1; ZBTB20; ZFY; HLF; LPIN2; E2F2; NR1H4; NFATC1; CD3D; SSX1; ZNF528; NCOA4; NSD1; STAT5A; ZFPM2; ZNF117; DDX17; ZNF835; ZNF165; EGR2; HMG20A; ZNF85; KLF4; EGR4; ZNF292; SOX5; PEG3; SMARCA2; ZNF274; TFDP2; PLAG1; ADNP; ZNF672; NR6A1; TMF1; PNRC1; NFYA; MAF; GRHL2; CARF; MXD4; ID1; BRD7; ZNF141; IKZF1; PIR; ZNF132; ZNF671; TFCP2; AFF4; ZNF180; RORC; FOXE1; ZNF331; PHF8; SMARCA5; ARNT; WNT4; SP1; TAF4; ZBED2; CAMTA1; OVOL1; ATF7IP; CBFA2T3; ZFP2; ZNF136; TCF21; BACH1; AEBP1; CBX5; STAT2; PRMT2; MLXIPL; E2F5; NCOA2; NPAT; CIITA; ZNF711; RSF1; HOXB2; OVOL2; MXD1; PITX1; RBM14; MED12; NFIL3; BACH2; POU6F1; ZNF33B; HCFC1; TCF7; GON4L; ZNF510; PBXIP1; TBR1; ZNF813; TLX1; ASH2L; BCL11B; EP400; ZNF442; VGLL1; SOX3; IKZF2; TRIM33; LYL1; EMX2; E4F1; HDAC11; KDM5D; RERE; CBX7; NFE2; ZNF665; BPTF; BNC1; HNF1B; SRY; GTF2I; TOPORS; BARX2; KLF11; RAX; ZNF225; ZBTB3; TERF1; IKZF3; NFIX; HSBP1; ZNF10; NAB2; MYBL1; CUX2; ZNF764; PRDM1; KLF10; ZNF75D; TFE3; SUV39H1; ZNF43; ZNF415; MSC; ASCL1; ZNF91; POU4F1; STAT5B; JAK2; SOX21; TCF25; AHR; ZNF334; EPAS1; ZNF571; SSBP2; KMT2A; ZBTB44; KAT5; TAF5; SPIB; LEF1; HDAC6; ZNF287; SMAD2; NCOA3; NFATC4; SSBP3; ZNF629; ZNF721; ECD; STAT4; ZNF205; LIMD1; NFE2L3; HSF4; NR1I2; ARID3A; SOX18; BAZ2A; ZNF93; TEAD1; LIN28A; IL16; RBPJ; KAT6A; ZKSCAN8; ZNF557; SNAI2; MED20; ZNF675; RFX7; MED21; YBX2; NFE2L2; ZNF460; ARRB1; ZNF552; PBX2; RFC1; THAP11; RELB; BHLHE40; ISL1; ZNF384; ZIC3; ZNF816; YAP1; BAZ1B; EHF; HR; FLI1; MKL2; PAWR; ZNF83; MECOM; ID4; CREBL2; ZNF443; IRF4; ZNF611; ZNF337; ZNF350; SMAD7; TWIST1; IFNB1; CTNNB1; SLC2A4RG; ZSCAN18; ELF3; PLAGL2; NR2F1; TDRD3; ZNF160; IRF6; TRIM22; PLAGL1; SPDEF; ING4; MITF; KMT2B; DNMT3B; AFF1; GFI1; ZNF587; BNC2; PPARG; FOXL2; FOXO4; BCOR; SAFB; FOXF1; NCOR1; ZNF544; RREB1; NANOG; MLXIP; ZNF208; ZBED1; CXXC1; ZNF189; ARNTL2; GATA6; ZEB1; TRIM24; MBD4; TCF7L1; NCOA1; PHIP; GLI3; LZTS1; MEF2C; TULP4; ZNF492; BRCA1; TRIP11; HMGB2; GATA3; HIPK2; ZNF14; RARA; TBL1X; ZNF107; MAGED1; BTG1; PRDM2; NR3C2; TRIM25; HHEX; ARNT2; ZFP36L2; WT1; POU5F1B; GABPA; HMGA2; PGR; FOXG1; ARID5B; NR1H3; OSR2; HMGN3; IFI16; HOXC4; SMAD1; SOX17; INSM1; CALCOCO1; CRYM; RORA; ESR1; REL; ETS2; NR4A1; BBX; ZHX2; FOXO1; CCNE1; CARHSP1; BHLHE41; TSC22D3; NR1D2; NR4A2; MYCN; KLF2; SAP30; TBX2; PSIP1
Down-regulation	408	PUF60; LOXL2; CDK2; DRAP1; NRIP1; SCAND1; HOXA5; GTF2A2; HDAC2; RUVBL1; PSMD9; GMNN; ATF5; ITGB3BP; ZNF593; RFX5; C1QBP; IKBKAP; ENY2; DNMT1; BCL3; VPS72; HDAC3; ZNF580; RBM39; SRF; ATF4; SUB1; ILF2; SUPT4H1; ZNF131; MYC; TSG101; TDP2; BIRC2; PCGF1; RNF138; ZNF410; HOXA10; RUVBL2; VEZF1; FLNA; FOXJ3; WWC1; GTF3A; UIMC1; CBX3; SFPQ; AES; PATZ1; HOXA4; RNF6; ZNF24; ZNF446; HOXA7; BRD8; PIAS4; CDYL; LMCD1; SF1; MTF2; APEX1; AIP; APBB1; USP16; CHD1; MED13; TAF10; ZNF146; PBX1; MED24; TGFB1I1; CREB3L2; ABT1; DAXX; HMGXB3; ARID1A; MAZ; NPM1; PMS1; DACH1; ZNF263; TAF6; USP21; HMGXB4; KMT5A; BMI1; SIRT7; IRF7; ERCC3; RRN3; CEBPZ; HOXD11; ZMIZ1; SP2; CNOT3; WIZ; SPEN; ZNF140; ZZZ3; ERF; MED27; ARID5A; ZMYM2; UBP1; RYBP; ZNF536; KLF5; NKRF; DR1; HOXD10; MTDH; ZNF324; HDAC7; MLLT10; ZNF646; DEAF1; ZFHX3; SMARCD1; TRIP4; CTBP2; EDF1; MED6; PHF1; NHLH2; SP110; ZNF668; POU3F2; HLX; BRD4; ZNF45; CCNC; TADA3; SMAD3; RNF4; WDHD1; BATF3; MLX; HOXD13; VSX1; ERBB2; ELK3; RXRB; ACTL6A; PSMC3IP; TRIB3; TRIM16; BTF3; SNW1; PQBP1; CENPF; NEDD8; TBL1XR1; WHSC1; ETV4; ARID4B; ARL2BP; VGLL4; ZBED4; RBBP8; TAF5L; ZNF444; CRX; TCEA1; PTRF; ZNF35; ZNF177; PDLIM1; MEF2A; NCOA6; SUPT6H; ESRRG; MSL3; GMEB2; SIN3B; LITAF; MED17; BASP1; PTTG1; E2F6; ID2; ZKSCAN5; MED23; E2F3; KLF13; NR2E1; MYT1; LDB1; ZBTB7A; HOXB13; FOS; HOXB9; IRF3; HOXD1; MXD3; STAT1; GTF2F1; CALR; MYOG; TAF7; DNAJC1; ZNF32; ZNF654; BRCA2; NR2F2; ZFHX4; RBFOX2; TAF11; HOXB3; ZSCAN12; SP3; ZNF562; SETD3; NCOR2; CITED1; SETDB1; HOXA11; PREB; EWSR1; PMF1; SRCAP; ZNF512B; WDR77; CBFB; MEF2D; NOC2L; TFAP2C; PSMC3; HSF1; TBX6; HOXD9; ZSCAN5A; NFIB; PSPC1; ZNF7; PA2G4; E2F8; SMARCB1; CEBPG; HLTF; MSX1; ATN1; DEK; TOB1; DMTF1; CREB5; FOXC1; SIRT2; PRRX2; BCLAF1; MECP2; ZMIZ2; CERS6; TSHZ2; KLF7; IRX4; NPAS2; CHD9; ZNF195; PPRC1; ZNF394; UBE2B; ETV5; MYF5; NRL; SNIP1; RAD21; ZMYND11; ZNF639; RFXANK; FOXN3; RCOR1; BTAF1; CBX4; KAT2A; RLF; YEATS4; ERG; MAML1; ZNF211; TCF3; RAN; TSC22D2; KAT6B; TEAD3; RNF14; TEAD4; ZNF354A; SUPT3H; YBX3; MYNN; PAXBP1; EYA1; YWHAB; KDM5C; WWTR1; TOX4; NONO; ATF2; NR1H2; THAP4; RBL1; BRF2; CRY1; DLX2; CERS4; PBRM1; RXRG; HMGB1; CREG1; TRIP6; HOXC6; SMAD4; RNF10; ZNF467; JARID2; INSR; TLE2; EN1; RNF111; PITX2; POLR3F; EP300; CARM1; ELF1; FOSL2; HIRA; ZBTB11; VDR; URI1; ZNF224; ZNF266; PCGF2; TAF1D; SAFB2; IRX5; ESRRA; ARNTL; TP63; JUNB; YBX1; XRCC6; MTA1; MED1; FOXF2; BRD2; SOX10; HOXD3; SP100; SIX2; TERF2; PBX3; KLF6; ZNF692; LZTR1; BRIP1; CEBPA; TCF4; TGFB1; HOXB6; MYBBP1A; TRIM29; HDAC1; ING3; EYA2; MTA2; SREBF1; FOXD1; YEATS2; COPS5; TGIF2; CRK; ZNF239; ZNF532; CEBPB; ZNF302; ERBB4; NR2C1; CHD8; NAB1; HOXB7; BCL6; CNOT6; MYRF; JUND; CNBP; SIX1; TCF7L2; SOX9; ZBTB18; STAT3; HIVEP1; JUP; SOX11; TBX3; TFAM; SMARCD3; CREB1; ZMYND8; HDAC9; MBD2; ZNF124; HSF2; PAX5; ZEB2; ZBTB16; IRF8; DLX5