Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50147	Isorotenone	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	247	SSBP2; ZNF331; NEUROD1; GATA2; HIC2; LMCD1; CEBPD; ZFPM2; ZNF131; NCOA3; SSX1; PITX1; ZNF44; NR1H2; KLF3; MYF6; CREM; PRDM10; ANKRD1; PAX9; FOXL2; HES1; MLXIP; BRWD1; PIR; MYBL1; TRIM24; EMX2; CDK8; JUP; FOXE1; PIAS1; EP300; NCOA1; BARX2; ZNF281; ZNF227; CUX1; TEAD3; TAF12; TFE3; GATA4; NRIP1; OVOL1; PATZ1; GFI1B; ZNF701; AFF1; PHIP; CREBZF; GATA1; NR5A1; TDRD3; TCF7; CHD2; THAP7; CSDC2; MXD4; NR1H4; NFYB; SOX17; ZIM2; THAP10; NR4A1; ZNF45; ZHX2; POU6F1; LIMD1; HDAC6; ZBTB20; SOX18; PEG3; ZNF239; HR; SKI; VGLL1; VGLL4; KDM4A; ZXDC; KAT2B; RBL1; ZNF225; ZNF160; BRD7; PLAG1; POU1F1; ZNF219; ZNF721; ZNF33B; LYL1; PROP1; ZNF623; TRPS1; HMG20A; ZNF667; ZNF550; PRKDC; PAX8; ZNF93; ZNF665; KLF1; ZNF32; TBX1; UBTF; ZBTB25; BRPF1; RB1; ARID3A; PURA; ZNF573; ZNF695; BCL11B; ZBTB16; KAT6A; NR5A2; ZNF510; SND1; PSPC1; ZNF440; ZNF611; KDM5A; BNC1; SOX3; ZNF688; PAX5; SOX13; SPIB; ZNF778; ZNF215; TRIP11; ZNF84; FOXJ1; KMT2A; GRHL2; ZNF432; HSF1; PSMC3; WWP1; PML; NFE2L2; NKX2-2; EP400; ELK4; ZNF85; ZNF140; SP140L; ZNF710; NR4A3; CITED2; ZNF10; MITF; ZNF268; ZFP36L2; CBX7; FHL5; EYA2; HOXC6; ZNF222; SAP130; PGR; LHX3; TFEC; FOXN3; LPIN2; UBE2B; POLR3C; ZNF75D; RBPMS; NFE2; NKX2-1; ZNF273; HMGB3; ZNF248; HESX1; DDX54; PAWR; ZNF83; ZNF430; MED15; DNAJC1; MAFG; ELF4; RCOR3; ZNF571; IRF5; EPAS1; ELF3; TAF5; GATA6; TRIM32; SMARCA2; YEATS2; TRIM33; JAK2; FLNA; ZNF492; RXRA; AGO2; MNDA; PAX6; CBFA2T3; E2F8; CD3D; TFEB; FOSL2; FOXC1; ZNF516; TRIM29; ZNF43; ELF5; CREB3L1; ZNF350; KAT6B; FOXG1; HMGB2; NANOG; WT1; POU2F1; MAF; TCF20; MTF2; POU2AF1; TAF9B; PCGF2; MEIS1; ZNF532; TRIM22; TAL1; STAT2; TBX3; SMARCB1; RUNX3; ARNTL; ZMIZ1; ZMYND8; OSR2; FOXA2; MEIS2; TOPORS; TBL1XR1; MYB; LIN28A; ZNF91; CREG1; ATF3; BHLHE41; NR4A2
Down-regulation	298	HOXA5; TLE1; SCAND1; ATF1; ZNF589; HDAC2; RFX5; ATF6; CERS6; DEK; LOXL2; GTF2IRD1; GTF2A2; ATF5; NUP62; SERTAD2; STAT6; PTTG1; PCGF1; CDC5L; CCNH; TAF10; TAF9; NFKBIA; HIF1A; PHF20; ZNF146; ILF2; SUB1; TCEA2; C1D; THAP4; HOXB6; CAMTA1; ATF2; ZFP64; USP16; HOXA10; DRAP1; MDM2; SMAD2; DEAF1; MTDH; RBBP8; HDAC4; TRIP6; MLXIPL; RUVBL2; HOXB2; HOXB5; NPAS1; SUMO1; ZFHX4; REST; CDYL; SMARCA4; RNF4; ELK3; NAB1; MAZ; GCFC2; DACH1; IKBKAP; BCL10; STAT5B; GMNN; HOXB3; BCLAF1; CCNA2; ZBTB32; TRAF6; CENPB; KAT2A; RFXANK; DNAJC2; ERCC3; PRRX2; CBFB; CRYM; CCDC59; MGA; TFAM; SP3; PDLIM1; PBX3; RNF138; RBM39; TAF7; ARNT2; NFKBIB; MED21; COPS2; DLX2; ALX1; SHOX2; RNF2; ID3; ISL1; CRY1; BAZ2A; RXRB; C1QBP; FOXD1; ID2; BIRC2; AIP; CHD3; MNT; TCERG1; LITAF; ERCC2; ZBTB11; RBPJL; HOXA4; SNAI2; HBP1; NELFB; URI1; HOXA6; NFKB1; ZNF671; MZF1; THRAP3; NFIL3; THAP3; SMAD3; ITGB3BP; CSDE1; NKRF; DR1; CTR9; MXI1; HOXD1; ZNF783; WWC1; SPEN; ZZZ3; PHF8; HOXA7; TSG101; DPF2; BCL11A; ARID4A; SUPT4H1; ZNF217; SP100; RELA; KMT2B; ID1; PMS1; TBX6; PEX2; ZNF580; PNRC1; MAML1; MYCBP; IRF3; ZNF408; HOXB9; CUX2; TCF4; NR1I2; REPIN1; TWIST1; FOXO4; TRIB3; ENY2; HLTF; NSD1; TFCP2; MEOX1; MED1; SP2; HOXD9; GFI1; EDF1; EGR1; RING1; HOXB13; POU3F2; KLF13; ADNP; ZMIZ2; FOXM1; SATB2; SREBF2; ETV4; AHR; CHD1; BTF3; HIVEP1; EZH2; TSC22D2; BRD3; EHMT2; TCF12; WIZ; ERBB2; CREB5; CHD7; NR0B1; SMAD4; ZNF444; ARID5B; ZNF232; DBP; MDFI; MED13; SRCAP; ATF6B; MSX1; IRX4; KDM5D; DDIT3; ACTL6A; TCF25; ZNF536; CXXC1; SIX1; DMTF1; ZBTB7A; RUNX1; HIPK1; ZNF668; ZNF24; RFC1; TP53; CEBPG; YWHAB; WWTR1; KLF7; NCOR2; ARID5A; PAXBP1; ASXL1; PSMC3IP; TCF7L2; MAFB; BCL6; SIM2; JUND; FOXN2; BRD2; PBX1; E2F3; MYRF; SOX11; NFIC; CTBP1; FOXF1; ZSCAN16; AEBP1; YEATS4; COPS5; ZNF652; CCNC; IRF9; TSC22D4; ZBTB43; ZNF562; BMI1; BCOR; SOX9; EGR3; FOS; YAP1; TOX3; ZBTB18; ARID1A; ZBED1; IRF7; HOXB7; TTF2; ING3; VDR; HDGF; HEY1; TERF2; DAXX; TOB1; BRD4; NKX3-1; STAT1; NR2F2; ZNF587; FOSB; KLF10; BASP1; ZKSCAN1; ZIC1; ZEB1; MEOX2; MYCN; ETS2; NFATC3; GATA3; SOX2; NR3C1